Photo by Barbara Brogdon
Find 2 Star Hotels in Panacea, FL from AED 326
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Our top choices for Panacea 2-star hotels

8.8 out of 10, Excellent, (946)
The price is AED 408
AED 455 total
includes taxes & fees
1 Jan - 2 January 2026
The price is AED 295
AED 326 total
includes taxes & fees
16 Dec - 17 Dec

8.4 out of 10, Very Good, (39)
The price is AED 507
AED 560 total
includes taxes & fees
15 Dec - 16 Dec

Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!
Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!Crawfordville
10.0 out of 10, Exceptional, (4)
The price is AED 569
AED 1,294 total
includes taxes & fees
15 Dec - 16 Dec

9.8 out of 10, Exceptional, (44)
The price is AED 504
AED 557 total
includes taxes & fees
1 Jan - 2 January 2026

Old Florida Fishing Cottage on the Forgotten Coast
Old Florida Fishing Cottage on the Forgotten CoastCarrabelle
9.8 out of 10, Exceptional, (8)
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Panacea.

The Lodge at Wakulla Springs
550 Wakulla Park Dr Crawfordville FL
9.2/10 Wonderful! (1,001 reviews)
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Learn more about Panacea
Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Top Panacea Hotel Reviews

The Panacea Motel
10/10 Excellent

Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay
10/10 Excellent
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Panacea Hotels by Star Rating
Stay near popular Panacea attractions
- Hotels near Bald Point State Park
- Hotels near USS Mohawk CGC Veterans Memorial Reef
- Hotels near Wakulla Springs State Park
- Hotels near Apalachicola National Forest
- Hotels near St. Marks National Wildlife Refuge
- Hotels near St. Marks Lighthouse
- Hotels near St. James Bay Golf Club
- Hotels near Ochlockonee River State Park
- Hotels near Crooked River Lighthouse
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- Beach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views
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- Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay
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- Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi
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