A calm river with boats, lush greenery, and a clear blue sky.

Find 4 Star Hotels in Big Pine Key, FL from AED 745

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Check availability on Big Pine Key 4 Star Hotels

Tonight
29 Sep - 30 Sep
Tomorrow
30 Sep - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Big Pine Key 4-star hotels

A swimming pool surrounded by palm trees and lounge chairs.
A beach scene with a wooden deck, palm trees, and a gazebo-like structure.
A spacious living room with a wooden coffee table, a striped sofa, and a television on a wooden cabinet.
A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.

1. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
AED 673
AED 992 total
includes taxes & fees
19 Oct - 20 Oct
Tranquility Bay Beachfront Hotel and Resort
A marina with boats docked, a lighthouse, and a resort with outdoor seating.
A room with two sofas, a round coffee table, and a small side table with a vase.
A bar area with a long counter, multiple bar stools, and a view of the marina with boats and palm trees.
A spacious lobby with a central round table, surrounded by wicker chairs, large potted plants, and decorative lanterns.

2. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United States
Rick
AED 539
AED 745 total
includes taxes & fees
11 Oct - 12 Oct
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A pool area with palm trees and a view of the ocean.
A beach with a wooden walkway leading to the water, palm trees, and a clear sky.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.

3. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
AED 643
AED 900 total
includes taxes & fees
28 Oct - 29 Oct
Grassy Flats Resort & Beach Club
A large hotel with a pool, multiple balconies, and palm trees.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.
A modern living room with a beige sectional sofa, large windows with wooden blinds, and a view of a marina and beach.
A beach with clear water and gentle waves.

4. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
An aerial view of a coastal resort with multiple buildings, a marina, and clear blue waters.
A poolside area with lounge chairs and palm trees.
A spacious dining area with a long table, wicker chairs, and hanging wicker lamps.

5. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
Property grounds
Pool
Dining
Living room

6. Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax
Marathon Shores
Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax
Pool
Property grounds
Pool
Exterior

7. Indigo Reef Marina Homes by Pack and Relax

Indigo Reef Marina Homes by Pack and Relax
Marathon
Indigo Reef Marina Homes by Pack and Relax
Pool
Lake
Balcony
Aerial view

8. Indigo Reef Marina Pet Friendly Homes by Pack and Relax

Indigo Reef Marina Pet Friendly Homes by Pack and Relax
Marathon
Indigo Reef Marina Pet Friendly Homes by Pack and Relax
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Big Pine Key.
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
AED 678
AED 979 total
30 Sep - 1 Oct
includes taxes & fees
9.2/10 Wonderful! (1,292 reviews)
Isla Bella Beach Resort & Spa
Sea Glass Cove

Sea Glass Cove

59720 Overseas Hwy Marathon FL
Get ratesSea Glass Cove
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colorful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

See all hotels in Big Pine Key
A beach with a palm tree, clear blue water, and a bridge in the distance.

Top Big Pine Key Hotel Reviews

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent
"Que no cierren la piscina tan temprano. Por lo demás todo excelente"
Nieves 2-night trip
Posted 17 hours ago
Tranquility Bay Beachfront Hotel and Resort

Frequently asked questions

What are the best 4-star hotels in Big Pine Key?
Make unforgettable vacation memories in Big Pine Key at Little Palm Island Resort & Spa - A Noble House Resort. Highly recommended by Expedia travelers, this 4-star hotel offers lots of amenities for a comfortable and relaxing stay.
How much does it cost to stay in a 4-star hotel in Big Pine Key?
To find a 4-star hotel in Big Pine Key that fits your budget, use Expedia's handy filters. Take a look at the available options during your vacation dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly stay first.
  • Search for the lowest price from AED 979
What's the difference between 5-star and 4-star hotels in Big Pine Key?
Treat yourself to luxury living during your Big Pine Key getaway by checking in to a 4-star hotel. As well as featuring upscale accommodations, these retreats are usually packed with amenities like large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and unforgettable one. 24-hour concierge assistance, elegant furnishings and world-class dining are only the start of the exclusive services and conveniences you'll likely have access to.