Find 4 Star Hotels in Big Pine Key, FL from AED 559

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Check availability on Big Pine Key 4 Star Hotels

Tonight
3 Sep - 4 Sep
Tomorrow
4 Sep - 5 Sep
This weekend
5 Sep - 7 Sep
Next weekend
12 Sep - 14 Sep

Compare Big Pine Key 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Big Pine Key 4-star hotels

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
2 outdoor pools, pool umbrellas, sun loungers

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4.0 star property
8.8 out of 10, Excellent, (1283)
"Beautiful property!"
The price is AED 559
AED 773 total
includes taxes & fees
9 Sep - 10 Sep
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Tranquility Bay Beachfront Hotel and Resort
3 outdoor pools, sun loungers

Tranquility Bay Beachfront Hotel and Resort

4.0 star property
8.8 out of 10, Excellent, (1001)
"Love the place we had a great time"
The price is AED 824
AED 1,163 total
includes taxes & fees
23 Sep - 24 Sep
Tranquility Bay Beachfront Hotel and Resort
Marlin Bay Resort & Marina
Exterior

Marlin Bay Resort & Marina

4.0 star property
Marlin Bay Resort & Marina
The Reef at Marathon, Florida Keys
Deluxe Villa | Private kitchen | Full-size fridge, microwave, oven, stovetop

The Reef at Marathon, Florida Keys

4.0 star property
9.4 out of 10, Exceptional, (8)
"It’s always been my favorite. The villas fit all my needs. Fantastic location and friendly staff."
The Reef at Marathon, Florida Keys
Key Colony Beach Paradise
Fridge, microwave, oven, stovetop

Key Colony Beach Paradise

4.0 star property
10.0 out of 10, Exceptional, (4)
Key Colony Beach Paradise
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly
Outdoor spa tub

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

4.0 star property
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly
Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen
Smart TV, printers

Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

4.0 star property
Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen
Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax
Villa, 3 Bedrooms | Balcony

Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

4.0 star property
Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax
Indigo Reef Marina Pet Friendly Homes by Pack and Relax
Villa, 3 Bedrooms | Pool | Outdoor pool

Indigo Reef Marina Pet Friendly Homes by Pack and Relax

4.0 star property
Indigo Reef Marina Pet Friendly Homes by Pack and Relax
Indigo Reef Marina Homes by Pack and Relax
Villa, 3 Bedrooms | Pool | Outdoor pool

Indigo Reef Marina Homes by Pack and Relax

4.0 star property
Indigo Reef Marina Homes by Pack and Relax
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Big Pine Key.
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard, MM 47, Marathon, FL
The price is AED 787 per night from Sep 10 to Sep 11
AED 787
AED 1,102 total
10 Sep - 11 Sep
includes taxes & fees
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PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colorful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

See all hotels in Big Pine Key
Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

Top Big Pine Key Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What are the best 4-star hotels in Big Pine Key?
Make unforgettable vacation memories in Big Pine Key at Little Palm Island Resort & Spa - A Noble House Resort. Highly recommended by Expedia travelers, this 4-star hotel offers lots of amenities for a comfortable and relaxing stay.
How much does it cost to stay in a 4-star hotel in Big Pine Key?
To find a 4-star hotel in Big Pine Key that fits your budget, use Expedia's handy filters. Take a look at the available options during your vacation dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly stay first.

  • Search for the lowest price from AED 787

What's the difference between 5-star and 4-star hotels in Big Pine Key?
Treat yourself to luxury living during your Big Pine Key getaway by checking in to a 4-star hotel. As well as featuring upscale accommodations, these retreats are usually packed with amenities like large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and unforgettable one. 24-hour concierge assistance, elegant furnishings and world-class dining are only the start of the exclusive services and conveniences you'll likely have access to.