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Find 4 Star Hotels in O Brien, FL
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Compare O Brien 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
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O Brien Hotels by Star Rating
Stay near popular O Brien attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River State Park
- Hotels near Lake City Mall
- Hotels near Ichetucknee River
- Hotels near North Florida Speedway
- Hotels near Southside Sports Complex
- Hotels near Santa Fe River
- Hotels near Poe Springs Park
- Hotels near O'Leno State Park
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Southside Recreation Complex
- Hotels near Columbia County Courthouse
- Hotels near Big Shoals State Park
- Hotels near Lafayette Blue Springs State Park
- Hotels near Stephen Foster Folk Culture Center
- Hotels near Stephen Foster State Folk Center
- Hotels near Troy Spring State Park
Explore more hotels
- Quality Inn & Suites Live Oak I-10 Exit 283
- Holiday Inn & Suites Lake City, an IHG Hotel
- Hampton Inn & Suites Lake City
- Tru by Hilton Lake City
- Baymont by Wyndham Lake City
- Royal Inn
- Days Inn by Wyndham Lake City I-10
- Super 8 by Wyndham Lake City
- Americas Best Value Inn Alachua
- Holiday Inn Express Hotel & Suites LIVE OAK, an IHG Hotel
- Quality Inn White Springs Suwanee
- Quality Inn Lake City
- Hampton Inn & Suites Alachua I-75
- Home2 Suites by Hilton Lake City
- Palms Garden Inn
- The Blanche
- Regal Inn
- Driftwood Inn
- Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
- Fairfield Inn & Suites Lake City