Find 4 Star Hotels in Upstate South Carolina, SC from AED 433

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Check availability on Upstate South Carolina 4 Star Hotels

Next weekend
12 Jun - 14 Jun
In two weeks
19 Jun - 21 Jun

Our top choices for Upstate South Carolina 4-star hotels

Exterior

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (503 reviews)
"Beautiful stay!"
United States
Shaina
The price is AED 988
AED 1,117 total
includes taxes & fees
5 Jul - 6 Jul
Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (810 reviews)
"Amazing hotel in the heart of Clemson!"
United States
Georgia
The price is AED 536
AED 595 total
includes taxes & fees
9 Jun - 10 Jun
The Shepherd Hotel Downtown Clemson
Restaurant

Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (732 reviews)
"One of my favorite hotels, lovely facility and great staff."
United States
Sara
The price is AED 622
AED 808 total
includes taxes & fees
14 Jun - 15 Jun
Hotel Hartness
Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services

Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (834 reviews)
"Great deal for the location. Apartment needed a little bit of love/attention."
Canada
Frédéric
The price is AED 510
AED 561 total
includes taxes & fees
5 Jul - 6 Jul
Mint House Greenville Downtown by Kasa
Exterior

The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,004 reviews)
"Beautiful stay"
United States
Christina
The price is AED 653
AED 729 total
includes taxes & fees
14 Jun - 15 Jun
The Westin Poinsett Greenville
Bar (on property)

Greenville Marriott

Greenville Marriott
4.0 star property
Greenville
8.6 out of 10, Excellent, (656 reviews)
"The staff was excellent and the shuttle service was very accommodating. "
United States
Towana
The price is AED 434
AED 493 total
includes taxes & fees
13 Jun - 14 Jun
Greenville Marriott
Lobby lounge

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (603 reviews)
"Very spacious room and bathroom. Staff and lobby area were great too."
United States
Melissa
The price is AED 488
AED 541 total
includes taxes & fees
1 Jul - 2 Jul
The Abernathy of Clemson
Front of property

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
Pendleton
10.0 out of 10, Exceptional, (89 reviews)
"Beautiful property and historic home. Lovely furnishings. Thoughtful touhes. Friendly and helpful staff. We would definitely stay here again. Highly recommend!!"
United States
Jane
The price is AED 420
AED 650 total
includes taxes & fees
18 Jun - 19 Jun
Liberty Hall Bed and Breakfast
Lobby

Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek
4.0 star property
Greer
Landing Apartments Greer - Sugar Creek
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (19 reviews)
"Swamp rabbit trail and restaurants very close "
United States
Martin
The price is AED 833
AED 1,219 total
includes taxes & fees
8 Jun - 9 Jun
The Station by Compo Hotels
Courtyard

Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (33 reviews)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is AED 1,576
AED 1,733 total
includes taxes & fees
7 Jun - 8 Jun
Hotel Domestique
Apartment (2 Bedrooms) | Interior

Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
4.0 star property
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
Studio, 1 Queen Bed (0 Bedroom) | Individually decorated, individually furnished, desk, laptop workspace

Landing Furnished Apartments - Spartanburg, SC

Landing Furnished Apartments - Spartanburg, SC
4.0 star property
Spartanburg
Landing Furnished Apartments - Spartanburg, SC
Apartment (3 Bedrooms) | Interior

Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
4.0 star property
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
Apartment (2 Bedrooms) | Interior

Private Balcony: Lake Keowee Home w/ Pool Access

Private Balcony: Lake Keowee Home w/ Pool Access
4.0 star property
Salem
Private Balcony: Lake Keowee Home w/ Pool Access
Apartment (2 Bedrooms) | Interior

Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
Lake Keowee Condo: Resort Pools & Lake Access!
Apartment (4 Bedrooms) | Interior

Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
4.0 star property
Salem
Salem Vacation Rental w/ Lake Keowee Access!
Apartment (2 Bedrooms) | Interior

Lake Keowee Resort Condo: Waterfront Balcony

Lake Keowee Resort Condo: Waterfront Balcony
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
"Very clean. Amazing amenities. Lake view that takes your breath away."
United States
Tiffany
Lake Keowee Resort Condo: Waterfront Balcony
Apartment (1 Bedroom) | Interior

Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
"Property is in a great community, and it was very clean and beautifully decorated."
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!
Apartment (3 Bedrooms) | Interior

5 Mi to Memorial Stadium & Beach: Modern Townhome

5 Mi to Memorial Stadium & Beach: Modern Townhome
4.0 star property
Central
5 Mi to Memorial Stadium & Beach: Modern Townhome
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Top Upstate South Carolina Hotel Reviews

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"Great room in a beautiful facility!"
Bryan 1-night trip
Posted 12 hours ago
Grand Bohemian Lodge Greenville, Autograph Collection

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Greenville Marriott is rated highly by many Expedia guests. Located in Greer, Upstate South Carolina, this 4-star hotel features lots of amenities to help make your stay comfortable and convenient.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from AED 433

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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