Find 4 Star Hotels in Upstate South Carolina, SC from AED140

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Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
Lobby
Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
9.4 out of 10, Exceptional, (241)
"Beautiful hotel with great restaurants and bars right on the river. Very walkable to everything Greenville. Will definitely stay here again. Staff was very nice. Valet was quick to get your car in and out. Bourbon bar was excellent. "
The price is AED 1,355
AED 1,491 total
includes taxes & fees
30 Sep - 1 Oct
Grand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness
Exterior
Hotel Hartness
4.0 star property
9.8 out of 10, Exceptional, (365)
"The property is gorgeous and secluded. Felt so welcomed and safe. I’ve been to boutique hotels before, but this one is on another level. Already planning another trip back just to stay longer and enjoy all of the amenities the property has to offer! "
The price is AED 615
AED 801 total
includes taxes & fees
6 Oct - 7 Oct
Hotel Hartness
The Shepherd Hotel Downtown Clemson
Room
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (386)
"Best hotel in Clemson. Perfectly located downtown. Nicely decorated hotel and rooms. Very comfortable beds. The roof top is a great place to hang out. "
The price is AED 657
AED 730 total
includes taxes & fees
30 Sep - 1 Oct
The Shepherd Hotel Downtown Clemson
The Westin Poinsett Greenville
Exterior
The Westin Poinsett Greenville
4.0 star property
9.2 out of 10, Wonderful, (1001)
"When traveling solo i always look for a hotel near restaurants ,shopping, parking, etc. This hotel is right in the heart of everything. Hotel rooms are nice with comfy pillows and mattresses. I would say the hotel in general needs an uplift...new carpets, paint etc. Overall a good experience. "
The price is AED 657
AED 745 total
includes taxes & fees
29 Sep - 30 Sep
The Westin Poinsett Greenville
Greenville Marriott
Exterior
Greenville Marriott
4.0 star property
8.6 out of 10, Excellent, (503)
"The property was well kept and inviting."
The price is AED 466
AED 530 total
includes taxes & fees
29 Sep - 30 Sep
Greenville Marriott
The Abernathy of Clemson
Room
The Abernathy of Clemson
4.0 star property
9.6 out of 10, Exceptional, (443)
"Great find in Clemson! Close to campus and walkable to many shops and restaurants. Free on-site parking. Friendly staff: front desk, bartender and housekeeper were all wonderful. Rooms are spacious, clean and functional. Would highly recommend and stay here again! "
The price is AED 584
AED 648 total
includes taxes & fees
29 Sep - 30 Sep
The Abernathy of Clemson
Mint House Greenville - Downtown
Room
Mint House Greenville - Downtown
4.0 star property
9.4 out of 10, Exceptional, (530)
"dope"
The price is AED 493
AED 558 total
includes taxes & fees
29 Sep - 30 Sep
Mint House Greenville - Downtown
Mint House Greenville - West End
Exterior
Mint House Greenville - West End
4.0 star property
9.2 out of 10, Wonderful, (59)
"Great spot! Clean, modern, great amenities and great location in the West End!"
The price is AED 512
AED 576 total
includes taxes & fees
6 Oct - 7 Oct
Mint House Greenville - West End
Liberty Hall Bed and Breakfast
Front of property
Liberty Hall Bed and Breakfast
4.0 star property
10.0 out of 10, Exceptional, (38)
"What a beautiful place! Couldn’t have been happier with my stay. Wonderful B&B, amazing breakfasts and clearly such attention to detail and pride of ownership. Keep up the good work!"
The price is AED 608
AED 675 total
includes taxes & fees
29 Sep - 30 Sep
Liberty Hall Bed and Breakfast
The Station by Compo Hotels
Terrace/patio
The Station by Compo Hotels
4.0 star property
10.0 out of 10, Exceptional, (1)
The Station by Compo Hotels
Hotel Domestique
Front of property
Hotel Domestique
4.0 star property
9.6 out of 10, Exceptional, (25)
"Enjoyed the small size of the hotel. Very friendly staff. Easy parking, close to the building. Gorgeous view from room (stayed in room named Colombiere) - mountain view and the water feature in courtyard. Ate dinner, breakfast and brunch at the hotel restaurant - it was certainly acceptable, but not my favorite meals. The spa treatment room is located in the fitness room, the hallway outside the treatment room is the main accesss to the restaurant for hotel guests - not as tranquil as I would...
The price is AED 1,539
AED 1,693 total
includes taxes & fees
10 Oct - 11 Oct
Hotel Domestique
Lake Hartwell Frank Howard Home Clemson
Front of property
Lake Hartwell Frank Howard Home Clemson
4.0 star property
Lake Hartwell Frank Howard Home Clemson
34 Allen St
Balcony
34 Allen St
4.0 star property
34 Allen St
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Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Greenville Marriott is rated highly by many Expedia guests. Located in Greer, Upstate South Carolina, this 4-star hotel features lots of amenities to help make your stay comfortable and convenient.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from AED140

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.
Does Upstate South Carolina have any 4-star all-inclusive resorts?
Enjoy a relaxing vacation experience where just about everything is included in one upfront price by using our “All inclusive” filter. Staying within budget is a breeze when your room, food and many activities are already taken care of. Eager for more options? Check out the terrific offers on our standard 4-star hotels in and around Upstate South Carolina too.
Are there any 4-star hotels near Greenville-Spartanburg Intl. Airport (GSP)?
For those early departures or late-in-the-evening flights, Greenville Marriott is a great option. This 4-star retreat is about 8 kilometers from Greenville-Spartanburg Intl. Airport (GSP), one of the main airports in Upstate South Carolina.