Are there any 5-star vacation rentals in Big Pine Key?

Although there aren't any 5-star vacation rentals in Big Pine Key on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your style by checking out our vacation rentals in Big Pine Key .

Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

Find 5 Star Hotels in Big Pine Key, FL from AED 668

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Compare Big Pine Key 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

"Very clean,walkable and quiet!a very good time with the family "

AED 1,548 total

includes taxes & fees

8 Jun - 9 Jun

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

1996 Overseas Highway, Marathon, FL

AED 668

AED 896 total

includes taxes & fees

8 Jun - 9 Jun

8.8/10 Excellent! (1,305 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Meet the local wildlife, splash in the shallows and enjoy the calm of the quieter Keys on this stretch of serene waterfront and wetlands.

See all hotels in Big Pine Key

Recent reviews of Big Pine Key hotels

5/5 Excellent

"The resort is just beautiful. You never feel crowded with choice of multiple pools. The on-site restaurant has great food and service and you can even eat right on the sand. Fire pits and music in the evening. Rooms are just as nice and clean with excellent views. Add the spa, market and a marina what more could you ask for."

A verified traveler from Bonita Springs stayed at Isla Bella Beach Resort & Spa

Posted 4 days ago

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Big Pine Key?

You’ll find a variety of pricing options for a 5-star hotel in Big Pine Key on Expedia. The amount you pay will depend on when you travel, length of your trip and other factors. Compare available properties for your desired dates and use our pricing and other filters to score the perfect high-end stay.

Search for the lowest price per night from AED 668

What makes a hotel 5 stars in Big Pine Key?

Outstanding guest service characterizes every 5-star hotel in Big Pine Key. From the moment you arrive, staff are at your beck and call, whether arranging valet parking or providing in-room massages. Additionally, hotels have to feature upscale amenities to meet the standard for a 5-star rating. These can include luxury bathrobes, saunas or spas, pools, gastronomic restaurants and knowledgeable concierge.

Are there any 5-star all-inclusive resorts in Big Pine Key?

Use Expedia’s filter tool to find a high-end escape in Big Pine Key where everything you need is included in the price. From there, narrow down your results for properties that have a 5-star rating and are listed as “All inclusive.” The most important thing to look forward to at these stays? Pure relaxation and indulgence.