Find 5 Star Hotels in Florida Keys from AED 928
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Florida Keys 5 Star Hotels
Tonight
6 Aug - 7 AugTomorrow
7 Aug - 8 AugThis weekend
7 Aug - 9 AugNext weekend
14 Aug - 16 AugOur top choices for Florida Keys 5-star hotels
AED 596
AED 939 total
includes taxes & fees
10 Aug - 11 Aug
AED 807
AED 1,129 total
includes taxes & fees
12 Aug - 13 Aug
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
AED 800
AED 1,183 total
13 Aug - 14 Aug
includes taxes & fees
8.2/10 Very Good! (1,013 reviews)
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
AED 901
AED 1,216 total
17 Aug - 18 Aug
includes taxes & fees
8.6/10 Excellent! (1,161 reviews)
Amara Cay Resort
80001 Overseas Hwy Islamorada FL
AED 586
AED 928 total
9 Aug - 10 Aug
includes taxes & fees
Still don't see what you're looking for?
See all properties in Florida Keys.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Florida Keys
Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.
See all hotels in Florida Keys
Top Florida Keys Hotel Reviews
Isla Bella Beach Resort & Spa
10/10 Excellent
"All around wonderful experience"
Frequently asked questions
How much does it cost to stay in a 5-star hotel in Florida Keys?
The amount you pay for a 5-star hotel in Florida Keys can vary depending on the time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.
- Search for the lowest price per night from AED 928
What makes a hotel 5 stars in Florida Keys?
In Florida Keys, a hotel needs to provide a specific level of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer special touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Keys?
Expedia's filters are the best way to narrow down what you're looking for. Select "5-star" and "All inclusive" to see the most luxurious properties in Florida Keys where your meals, room, activities and entertainment are included in the price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.