Find 5 Star Hotels in Mayo, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mayo 5 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mayo.
Steinhatchee Landing Resort

Steinhatchee Landing Resort

228 Ryland's Circle Steinhatchee FL
Get rates
Still don't see what you're looking for?
See all properties in Mayo.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mayo

Paddle through crystal-clear waters at Lafayette Blue Springs State Park where swimming and snorkeling reveal underwater caves and limestone formations. Explore the peaceful Suwannee River by kayak or visit Perry Spring, where locals gather for refreshing dips during hot summer afternoons.

See all hotels in Mayo
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top Mayo Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Mayo?
How much you pay for a 5-star hotel in Mayo can vary according to what time of year you travel and how long you plan to stay, among a range of factors. Take advantage of our price per night filter and other search tools to find the best deal on a high-end getaway.

  • Search for the lowest price per night

What makes a hotel 5 stars in Mayo?
Impeccable guest service is the hallmark of every 5-star hotel in Mayo. From the moment you arrive, staff attend to your every need, whether arranging customized tours or providing a nightly turn-down service. Additionally, hotels have to feature top-rate conveniences to meet the standard for a 5-star rating. These can include luxury toiletries, saunas or spas, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Mayo?
Use our convenient filters to find a luxury getaway in Mayo where most of what you need is included in the price. Next, refine your results for accommodations that have a 5-star rating and are described as "All inclusive." The first thing to look forward to at these stays? Relaxation and enjoyment.