Photo by Hideki Yamagata

Find 5 Star Hotels in San Francisco from AED 364

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on San Francisco 5 Star Hotels

Next weekend
In two weeks

Compare San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4025)
"Excellent location amazing service great food friendly staff "
The price is AED 403
AED 443 total
includes taxes & fees
23 Jun - 24 Jun
Hotel Riu Plaza Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"Very beautiful and comfortable place to stay, with all the amenities."
The price is AED 715
AED 786 total
includes taxes & fees
18 Jul - 19 Jul
JW Marriott Panama

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1000)
"Great hotel "
The price is AED 757
AED 833 total
includes taxes & fees
4 Jul - 5 Jul
Waldorf Astoria Panama

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1000)
"Beatiful!"
The price is AED 546
AED 601 total
includes taxes & fees
4 Jul - 5 Jul
The Westin Playa Bonita Panama

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (465)
"Amazing hotel!"
The price is AED 1,074
AED 1,182 total
includes taxes & fees
25 Jun - 26 Jun
Sofitel Legend Casco Viejo, Panama City

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1000)
"Love it here! "
The price is AED 670
AED 737 total
includes taxes & fees
18 Jul - 19 Jul
Hilton Panama

W Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"Clean and entire staff was a pleasure, customer service was top tier and the food by the pool deck was amazing. Will definitely stay here again. "
The price is AED 658
AED 724 total
includes taxes & fees
21 Jul - 22 Jul
W Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1002)
"Super nice hotel with spa. "
The price is AED 643
AED 707 total
includes taxes & fees
29 Jun - 30 Jun
Bristol Panama, a Registry Collection Hotel

Renaissance Panama City Hotel

5.0 star property
8.6 out of 10, Excellent, (19)
"excellent location, very nice property."
The price is AED 378
AED 416 total
includes taxes & fees
4 Jul - 5 Jul
Renaissance Panama City Hotel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (582)
"Beautiful hotel with great service and ambiance. "
The price is AED 768
AED 845 total
includes taxes & fees
11 Jul - 12 Jul
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Waymore Hotel Spa and Casino

5.0 star property
6.2 out of 10, (998)
Waymore Hotel Spa and Casino
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Francisco.
Still don't see what you're looking for?
See all properties in San Francisco.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about San Francisco

Like dining out? Get away to relaxing San Francisco!

Taisei Ramen
Tonkotsu flavor
#TroverFoodies
Photo by Hideki Yamagata
Open Photo by Hideki Yamagata

Frequently asked questions

What are the best 5-star hotels in San Francisco?
JW Marriott Panama is among the most popular picks around the Panama City neighborhood of San Francisco based on Expedia customer reviews. The Bahia Grand Hotel and Bristol Panama, a Registry Collection Hotel are other 5-star hotels in this area that rank highest with guests.
How much does it cost to stay in a 5-star hotel in San Francisco?
There are a variety of pricing options for 5-star hotels in San Francisco on Expedia. How much you'll pay will depend on when you travel, length of stay and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to score the ideal upscale stay.
  • Search for the lowest price per night from AED 364

What makes a hotel 5 stars in San Francisco?
Faultless guest service is the foundation of every 5-star hotel in San Francisco. From the minute you step through the door, staff ensure your every need is met, whether recommending activities or providing in-room massage treatments. Additionally, hotels have to feature upscale amenities to be considered for a 5-star rating. These can include luxury toiletries, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.