Find 5 Star Hotels in Santa Clara from AED 398

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Clara 5 Star Hotels

Tonight
5 Apr - 6 Apr
Tomorrow
6 Apr - 7 Apr
Next weekend
10 Apr - 12 Apr
In two weeks
17 Apr - 19 Apr

Our top choices for Santa Clara 5-star hotels

Outdoor pool, sun loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,201 reviews)
"Great place to stay, great staff, I had a good time in the hotel itself "
United States
Walana
The price is AED 506
AED 556 total
includes taxes & fees
6 May - 7 May
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent hotel, staff, and re"
United States
Joseph
The price is AED 1,032
AED 1,136 total
includes taxes & fees
20 Apr - 21 Apr
Waldorf Astoria Panama
2 restaurants, local cuisine

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,006 reviews)
"Very nice and cozy hotel I like this place a lot"
United States
Shahram Sean
The price is AED 1,021
AED 1,124 total
includes taxes & fees
1 May - 2 May
W Panama
Outdoor pool

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (241 reviews)
"Great staff and the food was amazing. "
United States
Nyrisha
The price is AED 592
AED 652 total
includes taxes & fees
7 Apr - 8 Apr
Hyatt Regency Panama City
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Very enjoyable stay"
Canada
Lynnette
The price is AED 996
AED 1,096 total
includes taxes & fees
26 Apr - 27 Apr
JW Marriott Panama
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (176 reviews)
"Very good hotel, well located. "
United States
Andrés
The price is AED 466
AED 513 total
includes taxes & fees
11 Apr - 12 Apr
Renaissance Panama City Hotel
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1,005 reviews)
"nice hotel, quality food, friendly staff, nice pools. "
United States
christopher
The price is AED 740
AED 814 total
includes taxes & fees
1 May - 2 May
The Westin Playa Bonita Panama
Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (630 reviews)
"Had a lovely stay"
United States
Olly
The price is AED 1,273
AED 1,400 total
includes taxes & fees
27 Apr - 28 Apr
Sofitel Legend Casco Viejo, Panama City
Couples treatment rooms, sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,005 reviews)
"Excellent Spa."
United States
Michael
The price is AED 711
AED 782 total
includes taxes & fees
1 May - 2 May
Bristol Panama, a Registry Collection Hotel
Sports facility

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1,000 reviews)
"Attentive and polite staff Good views Very clean"
Canada
rich steven
The price is AED 835
AED 918 total
includes taxes & fees
1 May - 2 May
Hilton Panama
View from property

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (683 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is AED 989
AED 1,088 total
includes taxes & fees
2 May - 3 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
View from property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very Good, (1,000 reviews)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Lobby

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1,000 reviews)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Clara.
Sheraton Grand Panama

Sheraton Grand Panama

Via Israel And 77th Street Panama City Panama
The price is AED 493 per night from May 2 to May 3
AED 493
AED 542 total
2 May - 3 May
includes taxes & fees
8.6/10 Excellent! (1,006 reviews)
Still don't see what you're looking for?
See all properties in Santa Clara.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

See all hotels in Santa Clara
Adobe

Top Santa Clara Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Breakfast was exceptional "
Lashana Jolene 4-night trip
Posted 5 hours ago
Hotel Riu Plaza Panama