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Hotel Museo Spa Casa Santo Domingo

4.5 star property
Luxury hotel with 2 restaurants and a full-service spa

Choose dates to view prices

Hotel Museo Spa Casa Santo Domingo, in Antigua's historical district, offers a poolside bar, spa treatments, and the Casa Santo Domingo Museum. Enjoy fusion cuisine at two restaurants. Central Park is a short walk away, and ziplining adds excitement to this cultural retreat.
VIP Access

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Gym
  • Pet friendly
The current price is AED 992
AED 1,255 total
includes taxes & fees
4 Nov - 5 Nov

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Room options

Available filters for rooms
Showing 13 of 13 rooms

View all photos for Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Jetted bathtub
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Spa Living (All rooms are different)

Standard Spa Living (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Standard Spa Living (All rooms are different)

9.0 out of 10
Wonderful
(9 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Private bathroom
  • Sleeps 2
  • 2 Double Beds

View all photos for Superior Suite Spa Living (All rooms are different)

Superior Suite Spa Living (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Superior Suite Spa Living (All rooms are different)

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room (All rooms are different)

Standard Room (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Standard Room (All rooms are different)

9.0 out of 10
Wonderful
(31 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Private bathroom
  • 19 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

Standard Room, 1 King Bed, Jetted Tub (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

10.0 out of 10
Exceptional
(5 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Jetted bathtub
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room (All rooms are different)

Deluxe Room (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Deluxe Room (All rooms are different)

9.8 out of 10
Exceptional
(12 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Private bathroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Executive Suite (All rooms are different)

Executive Suite (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Executive Suite (All rooms are different)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Private bathroom
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Exclusive Suite, 1 King Bed (All rooms are different)

Exclusive Suite, 1 King Bed (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Exclusive Suite, 1 King Bed (All rooms are different)

Highlights

Fireplace
Private hot tub
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Executive Suite, 1 King Bed (All rooms are different)

Executive Suite, 1 King Bed (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Executive Suite, 1 King Bed (All rooms are different)

10.0 out of 10
Exceptional
(1 review)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Private bathroom
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite (All rooms are different)

Junior Suite (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Junior Suite (All rooms are different)

9.6 out of 10
Exceptional
(4 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Private bathroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Suite (All rooms are different)

Deluxe Suite (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Deluxe Suite (All rooms are different)

10.0 out of 10
Exceptional
(5 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Pillowtop bed
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite (All rooms are different)

Suite (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Suite (All rooms are different)

10.0 out of 10
Exceptional
(3 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Private bathroom
  • 1 bedroom
  • Sleeps 2
  • 1 Double Bed

View all photos for Superior Suite, Jetted Tub (All rooms are different)

Superior Suite, Jetted Tub (All rooms are different) | 1 bedroom, premium bedding, minibar, in-room safe

Superior Suite, Jetted Tub (All rooms are different)

9.4 out of 10
Exceptional
(3 reviews)

Highlights

Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Jetted bathtub
  • Sleeps 4
  • 2 Double Beds

About the neighborhood

Map
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez, 3001

What's nearby

  • Las Capuchinas Convent - 5 min walk - 0.4 km
  • Central Park - 6 min walk - 0.6 km
  • Santa Catalina Arch - 8 min walk - 0.7 km
  • Antigua Guatemala Cathedral - 8 min walk - 0.7 km
  • La Merced Church - 9 min walk - 0.8 km

Getting around

  • La Aurora Intl. Airport (GUA) - 68 min drive

Restaurants

  • ‪Once Once - ‬5 min walk
  • ‪Coffea - Cafés Especiáles - ‬6 min walk
  • ‪El Refectorio - ‬1 min walk
  • ‪7 Caldos Antigua Guatemala - ‬1 min walk
  • ‪Patio De La Primera - ‬6 min walk

About this property

Hotel Museo Spa Casa Santo Domingo

Luxury boutique hotel near Casa Santo Domingo Museum
Close to Antigua Guatemala Cathedral and Central Park, Hotel Museo Spa Casa Santo Domingo provides a poolside bar, a terrace, and a garden. Indulge in a facial, a body wrap, and a body treatment at the onsite spa. At the two on-site restaurants, enjoy breakfast, lunch, dinner, and Fusion cuisine. Enjoy the health club, as well as activities like ziplining. In addition to a hair salon and dry cleaning/laundry services, guests can connect to free WiFi in public areas.
Other perks at this hotel include:
  • An outdoor pool
  • Free self parking
  • Full breakfast (surcharge), a roundtrip airport shuttle (surcharge), and an electric car charging station
  • Express check-out, ATM/banking services, and meeting rooms
  • Guest reviews speak highly of the helpful staff and first-rate property condition
Room features
All 132 rooms include comforts such as fireplaces and premium bedding, as well as perks like pillow menus and air conditioning.
Extra conveniences in all rooms include:
  • Rollaway/extra beds (surcharge) and cribs/infant beds (surcharge)
  • Bathrooms with tubs or showers and hair dryers
  • 42-inch Smart TVs with premium channels
  • Daily housekeeping and phones

Similar properties

Restaurant

Hotel Camino Real Antigua

  • Hot Tub
  • Spa
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 1,008 reviews
The price is AED 531
AED 746 total
includes taxes & fees
17 Nov - 18 Nov
Hotel Camino Real Antigua

Property amenities

Internet

  • Available in some public areas: Free WiFi

Parking and transportation

  • Electric car charging station on site
  • 24-hour roundtrip airport shuttle (surcharge)
  • Free self parking on site
  • Wheelchair-accessible parking available
  • Onsite parking includes off-street options

Food and drink

  • Daily full breakfast available 7:00 AM to 11:00 AM for a fee: USD 20 per person
  • 2 bars/lounges
  • 2 restaurants
  • A poolside bar

Restaurants on site

  • El Refrectorio
  • El Tenedor Del Cerro

Things to do

  • Full-service spa
  • Health club
  • Outdoor pool
  • Sauna
  • Steam room
  • Ziplining

Family friendly

  • Crib (surcharge)
  • Laundry facilities
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Guidebooks
  • Hair salon
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Water dispenser

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Tour and ticket assistance

Business services

  • Business center
  • Conference space
  • Meeting rooms

Outdoors

  • Garden
  • Terrace
  • Vegetable garden

Full-service spa

  • Aromatherapy
  • Body scrubs
  • Body wraps
  • Couples treatment rooms
  • Facials
  • Hot tub
  • Manicures/pedicures
  • Massage
  • Sauna
  • Spa open daily

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • No elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant

More

  • 1 building
  • 2 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Built in 1989
  • Comprehensive recycling policy
  • Local artist showcase
  • Smoking not allowed

Room amenities

Bedroom

  • Crib (surcharge)
  • Pillow menu
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 42-inch smart TV with premium cable channels

Food and drink

  • Limited room service
  • Minibar
  • Restaurant dining guides

More

  • Air conditioning
  • Connecting rooms available
  • Fireplace
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: midnight
Early check-in subject to availability
Late check-in subject to availability
Minimum check-in age: 18

Check-out

Check-out before noon
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
For any questions, please contact the property using the information on the booking confirmation

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 61 per pet, per night
Welcoming dogs only
1 total (up to 25 lbs per pet)
Pets cannot be left unattended
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are available for USD 48.8 per day
Cribs (infant beds) are available for USD 9.76 per day

Property payment types

Important information

Optional extras

  • Fee for full breakfast: approximately USD 20 per person
  • Airport shuttle fee: USD 60 per person (one-way)
  • Pet fee: USD 61 per pet, per night
  • Late check-out is available for a fee (subject to availability)
  • Crib (infant bed) fee: USD 9.76 per day
  • Rollaway bed fee: USD 48.8 per day

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards and cash
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
This property uses a grey water recycling system
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
This property charges a fee of USD 45 per night for use of the sofabed.

We should mention

This property does not have elevators
Reservations are required for massage services and spa treatments; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Guests under 18 years old are not allowed in the spa

Property is also known as

Casa Domingo
Casa Hotel Santo Domingo
Casa Santo Domingo
Casa Santo Domingo Antigua Guatemala
Casa Santo Domingo Hotel
Hotel Casa Domingo
Hotel Casa Santo Domingo Antigua Guatemala
Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo Hotel
Hotel Museo Spa Casa Santo Domingo Antigua Guatemala
Hotel Museo Spa Casa Santo Domingo Hotel Antigua Guatemala

Frequently asked questions

Does Hotel Museo Spa Casa Santo Domingo have a pool?

Yes, this property has an outdoor pool.

How much does it cost to stay at Hotel Museo Spa Casa Santo Domingo?

As of 3 November 2025, prices found for a 1-night stay for 2 adults at Hotel Museo Spa Casa Santo Domingo on 4 November 2025 start from $341.6, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hotel Museo Spa Casa Santo Domingo pet-friendly?

Yes, Hotel Museo Spa Casa Santo Domingo allows dogs (limit 1 total) with a maximum weight of up to 25 lbs per pet. There's a fee of USD 61 per pet, per night. Some restrictions may apply, so please contact the property for more details.

How much is parking at Hotel Museo Spa Casa Santo Domingo?

Self parking is free at this property.

What time is check-in at Hotel Museo Spa Casa Santo Domingo?

Check-in start time: 3:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.

What time is check-out at Hotel Museo Spa Casa Santo Domingo?

Check-out is at noon. Late check-out is available for a fee (subject to availability).

Does Hotel Museo Spa Casa Santo Domingo provide a shuttle to the airport?

Yes, there's an airport shuttle. A fee of USD 60 per person applies.

Where is Hotel Museo Spa Casa Santo Domingo located?

Located in Barrio de La Concepción, this luxury hotel is within a 10-minute walk of Casa Santo Domingo Museum, Central Park, and Antigua Guatemala Cathedral. Iglesia y Convento de Santo Domingo and Jade Maya Factory and Museum are just steps away.

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Reviews

Hotel Museo Spa Casa Santo Domingo Reviews

9.2

Wonderful

9.8

Cleanliness

9.4

Amenities

9.4

Staff & service

9.6

Eco-friendliness

9.6

Property conditions & facilities
Rating 10 - Excellent. 776 out of 1007 reviews
Rating 8 - Good. 126 out of 1007 reviews
Rating 6 - Okay. 48 out of 1007 reviews
Rating 4 - Poor. 31 out of 1007 reviews
Rating 2 - Terrible. 26 out of 1007 reviews

Reviews

10/10 Excellent

Axel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Will definitely be returning here!
Stayed 1 night in Oct 2025

10/10 Excellent

Gustavo

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent place!
Stayed 3 nights in Aug 2025

10/10 Excellent

JOSEPH

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice amenities and very good staff
Stayed 1 night in Sep 2025

10/10 Excellent

Kimarliea

Liked: Cleanliness, staff & service, property conditions & facilities
I loved this place so historically and the architect work is amazing
Stayed 2 nights in Jul 2025

10/10 Excellent

Ana Maria

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property is gorgeous and the staff takes pride in keeping it that way.
Stayed 1 night in Sep 2025

10/10 Excellent

Anny

Liked: Cleanliness, staff & service, property conditions & facilities
Always great!
Stayed 2 nights in Oct 2025

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The spa is extraordinary! The service of staff and cleanliness is remarkable! We will return and highly recommend this experience!
Stayed 1 night in Oct 2025

10/10 Excellent

César

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel as always
Stayed 1 night in Aug 2025

10/10 Excellent

Marieta

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful!
Stayed 1 night in Sep 2025

10/10 Excellent

Caitlin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This property is beautiful!! Everything was amazing. Staff wad great!! Restaurant and Spa were amazing!!
Stayed 1 night in Aug 2025

10/10 Excellent

Ana Aurora

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful Hotel! Comfortable bed, pillows and views are AMAZING!
Stayed 2 nights in Jun 2025

10/10 Excellent

Maria J

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to visit
Stayed 3 nights in Apr 2025

10/10 Excellent

Stephen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I wouldn’t look at any other hotel to stay at when revisiting Antigua! This is the place!! Front desk staff was a bit bumpy however.
Stayed 4 nights in Jul 2025

10/10 Excellent

Daniella

Liked: Amenities, property conditions & facilities
Absolutely stunning hotel in the heart of Antigua!
Stayed 3 nights in May 2025

10/10 Excellent

Joan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Our favorite place in Antigua. Been here 3 times in 25 years and won't stay anywhere else. While the hotel has changed (expanded) over the years, the service and customer service remain top-notch.
Stayed 5 nights in Jul 2025

10/10 Excellent

Patrick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel, friendly staff.
Stayed 2 nights in Apr 2025

10/10 Excellent

Luis

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel and Antigua is a must
Stayed 1 night in May 2025

8/10 Good

Isabel

Liked: Cleanliness
Beautiful hotel with excellent food,service and location.
Stayed 3 nights in Mar 2025

8/10 Good

Cassandra

Liked: Cleanliness, property conditions & facilities
Disliked: Amenities
Beautiful hotel. Amazing food at the restaurant on property. Loved the museums and the spa. Enjoyed the quiet and peacefulness
Stayed 5 nights in Jun 2025

4/10 Poor

Luis

Liked: Cleanliness, amenities, property conditions & facilities
Nice museums, worth the visit
Stayed 2 nights in May 2025

8/10 Good

Benjamin

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful property we really enjoyed our stay … I’m giving it 4 stars because the pool area was under construction.
Stayed 2 nights in Jun 2025

10/10 Excellent

ANA

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent !!!
Stayed 2 nights in Jul 2025

10/10 Excellent

Arnold

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff is great
Stayed 2 nights in May 2025

10/10 Excellent

Cory

Liked: Cleanliness, amenities, property conditions & facilities
Possibly the most incredible hotel we’ve ever stayed at. Ever.
Stayed 2 nights in Jun 2025

10/10 Excellent

Annette

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We loved staying at Santo Domingo with our girls - the pool and museums are lovely.
Stayed 1 night in Feb 2025