Antofagasta Region Vacations

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Top destinations in Antofagasta Region

A narrow dirt road lined with buildings and trees, with people walking and a stroller visible.

San Pedro de Atacama

San Pedro de Atacama
A desert landscape with sparse vegetation and distant snow-capped mountains.

María Elena

María Elena

Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

Toconao 460 San Pedro de Atacama Antofagasta
8.2/10 Very Good! (402 reviews)
"Staff very helpful and friendly, although no English. Happy to converse using translation tools. Swimming pool was closed due to it being winter, which I didn’t reslise when I booked. A couple of times there was no water, no electricity and no wifi, but staff worked to resolve the issue. Breakfast ..."

Reviewed on 18 July 2026

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Diego de Almagro San Pedro de Atacama
Hotel La Casa de Don Tomas

Hotel La Casa de Don Tomas

Calle Tocopilla Sitio 18 San Pedro de Atacama
Fully refundableReserve now, pay when you stay
AED 771
AED 771 total
29 Sep - 30 Sep
9.2/10 Wonderful! (442 reviews)
"Beautiful property. We only stayed for one night but would book it again if we can’t back to San Pedro."

Reviewed on 20 September 2026

Hotel La Casa de Don Tomas
Geotel Calama

Geotel Calama

Cobija 2273 Calama Antofagasta
AED 338
AED 338 total
2 Oct - 3 Oct
8.8/10 Excellent! (238 reviews)
"Great stay, lovely breakfast. Nice and quiet and easy walk to town square. Highly recommend"

Reviewed on 16 September 2026

Geotel Calama
See all 307 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Antofagasta Region attractions

A desert landscape with layered rock formations and sand dunes.

Valley of the Moon

9.2/10 (244 reviews)
Explore the great outdoors at Valley of the Moon, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.
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Ancient stone ruins with stepped terraces and walls in a desert landscape.
Photo by Mark Rentz

Pukara de Quitor Archaeological Site

8.4/10 (42 reviews)
You can find out about the history of Quitor with a trip to Pukara de Quitor Archaeological Site. You can seek out the local tours in this quaint area.
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Plaza de San Pedro de Atacama

8.4/10 (195 reviews)
You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.
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San Pedro Church

8.6/10 (64 reviews)
San Pedro Church is just one of the places to see in San Pedro de Atacama, so why not enjoy the other things to explore during your travels? You can seek out the local tours in this quaint area.
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Cerro Paranal Observatory

8.6/10 (4 reviews)
Commune with nature and explore the great outdoors at Cerro Paranal Observatory during your travels in Antofagasta. Amble around the area's seaside or visit its shops.
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Mall Plaza Calama

8.8/10 (9 reviews)
During your trip to Calama, you can enjoy retail therapy at Mall Plaza Calama. Discover the area's desert landscape and casinos.
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Chuquicamata Mine

7.6/10 (5 reviews)
Find out about the history of Calama when you take a trip to Chuquicamata Mine. Amble around the area's parks or visit its casinos.
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Tulor Archaeological Site

8.4/10 (6 reviews)
You can find out about the history of San Pedro de Atacama with a trip to Tulor Archaeological Site. You can seek out the local tours in this quaint area.
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