Antofagasta Region Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

    • payments icon
    Better together
    Save up to AED 148 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Top destinations in Antofagasta Region

San Pedro de Atacama as well as a small group of people
FlightsFlightsHotelsHotels

San Pedro de Atacama

San Pedro de Atacama

Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama
Diego de Almagro San Pedro de Atacama
3 out of 5
Toconao 460, San Pedro de Atacama, Antofagasta
Fully refundableReserve now, pay when you stay
The price is AED 430 per night from May 18 to May 19
AED 430
AED 430 total
18 May - 19 May
8/10 Very Good! (286 reviews)
Great location
"Perfectly nice place to stay. Very good value. Amazing location just metres from centre of San Pedro. Decent pool area. Breakfast was nice. Room was basic, cosy and clean. We only booked the day before so no complaints really. Stayed for 3 nights. If I was staying longer I would need a bigger room. ..."

Reviewed on 27 March 2025

Diego de Almagro San Pedro de Atacama
Hotel La Casa de Don Tomas
Hotel La Casa de Don Tomas
3 out of 5
Calle Tocopilla Sitio 18, San Pedro de Atacama
Fully refundableReserve now, pay when you stay
The price is AED 694 per night from May 21 to May 22
AED 694
AED 694 total
21 May - 22 May
9/10 Wonderful! (335 reviews)
"All good"

Reviewed on 2 May 2025

Hotel La Casa de Don Tomas
Holiday Inn Express Antofagasta by IHG
Holiday Inn Express Antofagasta by IHG
3.5 out of 5
Ave. Grecia 1490, Antofagasta, Antofagasta
Fully refundable
The price is AED 228 per night from May 25 to May 26
AED 228
AED 228 total
25 May - 26 May
8.8/10 Excellent! (312 reviews)
"Excelente opción, frente a la vía costanera"

Reviewed on 20 April 2025

Holiday Inn Express Antofagasta by IHG
See all 281 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Antofagasta Region

Vale dos Cactus http://www.phototravel360.com/americadosul/chile/atacama/

Plaza de San Pedro de Atacama

4/5(38 reviews)

You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.

Plaza de San Pedro de Atacama
Valle de la Luna showing desert views

Valley of the Moon

4.5/5(47 reviews)

Explore the great outdoors at Valley of the Moon, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.

Valley of the Moon
Second oldest church in Chile, completed in the 17th century in San Pedro de Atacama, town in the middle of the arid Atacama desert

San Pedro Church

4/5(15 reviews)

Find out about the history of San Pedro de Atacama when you take a trip to San Pedro Church. You can seek out the local tours in this quaint area.

San Pedro Church