Find Resorts & Hotels with Spas in Berkeley, MO

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Check availability on Berkeley Resorts & Hotels with Spas

Our top choices for Berkeley hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1004)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is AED 559
AED 714 total
includes taxes & fees
14 Dec - 15 Dec
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1493)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is AED 493
AED 594 total
includes taxes & fees
21 Dec - 22 Dec
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1001)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is AED 1,524
AED 1,782 total
includes taxes & fees
1 Jan - 2 January 2026
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is AED 1,833
AED 2,139 total
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Berkeley Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
" I felt very comfortable and safe while staying a Pear Tree. The breakfast was great and I looked forward to the popcorn in the evening"
Kathy 6-night trip
Posted 2 days ago
Pear Tree Inn St. Louis Near Union Station

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Frequently asked questions

Looking to vacation at a spa hotel in Berkeley?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers recommend the gourmet restaurants in Berkeley. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
What's there to see and do in Berkeley?
Take in the sights and attractions that Berkeley offers with a visit to St. Louis Union Station, Gateway Arch, and Blanche M. Touhill Performing Arts Center. If you have a little extra time during your trip, you might want to check out Westport Plaza and Hollywood Casino Amphitheatre.
What is a Berkeley spa hotel?
Spa hotels in Berkeley provide lodging and have an on-site spa which offers services like massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.