A dog running through a body of water with trees in the background.

Cairo Vacation Rentals

Q: What's the top vacation rental that Cairo has to offer?

Player Piano - Gym - Victorian - 4 Bed : This vacation home rental near Cairo offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

Dates

November 2026

December 2026

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Our top choices for Cairo vacation rentals

A compact kitchen with a granite countertop, a ceiling fan, and a view through a door to a living area with a couch and a patterned rug.

1. Quaint 1-bedroom tiny home with loft bed in charming Parkersburg

Parkersburg

Landon G.

AED 452 total

includes taxes & fees

9 Nov - 10 Nov

A staircase with a handrail and a sign that says 'Please' on the wall.

2. Cozy 1-bedroom tiny house in beautiful Parkersburg,WV

Parkersburg

AED 489 total

includes taxes & fees

9 Nov - 10 Nov

A modern kitchen with wooden cabinets, stainless steel appliances, and a central island.

3. Charming Ranch + Renovated + Convenient Location

Wood County

AED 625 total

includes taxes & fees

7 Dec - 8 Dec

A spacious kitchen with a large island, brick walls, and a chandelier.

4. Shopping District Apt | Heart of Historic Downtown

Marietta

Lydia O.

AED 797 total

includes taxes & fees

8 Nov - 9 Nov

A kitchen with wooden cabinets, a white countertop, a stainless steel stove, a microwave, and a chandelier.

5. Downtown Marietta Retreat

Marietta

alexa r.

6. Captain's Quarters | One Bed Condo Waterfront on Ohio River

Marietta

Marlene M.

AED 805 total

includes taxes & fees

8 Nov - 9 Nov

A cabin with a stone foundation, a wooden deck, and a staircase leading to a balcony.

7. Hillside Hideaway in Marietta, OH: 4 beds, 2 baths, stunning views!

Marietta

Jill B.

AED 817 total

includes taxes & fees

17 Nov - 18 Nov

A living room with a gray sofa, a round coffee table, and a fireplace with a mantel.

8. The Flat on Front Street

Marietta

Amy W.

AED 959 total

includes taxes & fees

8 Nov - 9 Nov

A deck with a table and chairs overlooking a lake, with a boat in the distance.

9. River Port | 3 Bed Condo Waterfront on Ohio River

Marietta

shannon m.

AED 1,047 total

includes taxes & fees

8 Nov - 9 Nov

A white house with a covered porch, steps leading to the entrance, and a brick pathway.

10. The Historic Buckley House - 4 En-Suites - Walk Downtown

Marietta

Holly L.

AED 2,085 total

includes taxes & fees

8 Nov - 9 Nov

A living room with a fireplace, a sofa set, and a floor lamp.

11. Close to everything in Marietta, OH- "Our Cozy Corner"

Marietta

Lonnie H.

AED 816 total

includes taxes & fees

29 Nov - 30 Nov

A deck with a table and chairs overlooking a river with a boat in the distance.

12. Dock Side | 2 Bed Condo Waterfront on Ohio River

Marietta

Andrew K.

AED 824 total

includes taxes & fees

8 Nov - 9 Nov

A wooden deck with a table and chairs, overlooking a calm body of water.

13. Harbor Master | 2 Bed Condo Waterfront on Ohio River

Marietta

NAM

AED 866 total

includes taxes & fees

8 Nov - 9 Nov

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Find vacation rentals that suit your style

Top Cairo Hotel Reviews

A hotel lobby with a reception desk, seating area, and a kitchen in the background.

Fairfield Inn & Suites Marietta

Marietta

10/10 Excellent

Anonymous traveler

A bedroom with a bed, two bedside lamps, a painting on the wall, a wooden headboard, and a window with curtains.

Aldeco Motel

New Matamoras

10/10 Excellent

Richard

A multi-story hotel with a covered entrance and a parking lot.

Microtel Inn & Suites by Wyndham Marietta

Marietta

10/10 Excellent

Cheryl

A spacious lobby with multiple seating areas, a reception desk, and a dining area.

Comfort Suites Marietta - Parkersburg

Marietta

10/10 Excellent

We were staying at this hotel to visit our daughter in college. We wanted to bring our dog with us, and we couldn’t have been more impressed with this hotel. I couldn’t believe the number of animals that were staying there. I love that this hotel was so welcoming. They even had a resident cat that roamed around the lobby. I would totally recommend this hotel if you are traveling with an animal

Regina

The Blennerhassett Hotel entrance with a covered porch, potted plants, and a flag.

The Blennerhassett Giovanni Hotel, Trademark Col. by Wyndham

Parkersburg

10/10 Excellent

Robert

A Holiday Inn Express & Suites hotel with a modern design, featuring a covered entrance and stone accents.

Holiday Inn Express & Suites Parkersburg East by IHG

Parkersburg

10/10 Excellent

Nora

A room with a large bed, a sofa, and a television.

The Hackett Hotel

Marietta

10/10 Excellent

Wendy

A hotel room with a sofa, a small table, a lamp, and a bed with a nightstand.

TownePlace Suites by Marriott Parkersburg

Parkersburg

10/10 Excellent

Anonymous traveler

A modern hotel with a flat roof, large windows, and a welcoming entrance.

Hampton Inn Marietta

Marietta

10/10 Excellent

Anonymous traveler

An outdoor patio with stone walls, a fire pit, and orange chairs.

Hampton Inn & Suites Parkersburg Downtown

Parkersburg

10/10 Excellent

john

A hotel lobby with a reception desk, two sofas, a coffee table, a potted plant, and a large window.

Sleep Inn & Suites Parkersburg - Mineral Wells

Parkersburg

10/10 Excellent

Felicia

A reception area with a modern design, featuring a glass door entrance, a reception desk with illuminated panels, and a wall-mounted light fixture.

Holiday Inn Express & Suites Parkersburg-Mineral Wells by IHG

Mineralwells

10/10 Excellent

Susan

A Hampton Inn hotel with a modern facade, a covered entrance, and a landscaped driveway.

Hampton Inn Parkersburg-Mineral Wells

Mineralwells

10/10 Excellent

Only stayed overnight for a wedding in the area, but could not have been more pleased with the experience. The room was large and really clean. Bathroom was also spacious and super clean as well. I arrived early for my check-in but they had my room available and I was able to grab a nap before the wedding. The bed was firm, but not uncomfortable. The manager was running the front desk and she was great! Before confirming that my room was ready, she had a quick conversation with a...

Scott

A grand lobby with a large wooden ship's wheel, arched windows, and a patterned carpet.

The Lafayette A grand Riverboat Era Hotel

Marietta

10/10 Excellent

My wife and I love historic hotels, and the Lafayette is over 100 years old. We had a king parlor suite on the 5th. floor with river view. It was very quiet and peaceful. We had drinks on the rooftop patio while watching barges and river boats travel back and forth on the Ohio River. We had supper in the bar which was outstanding. Great service, great prices, and historic bar atmosphere made it a very nice evening. We didn’t know while booking that it included a free breakfast. So I was...

Thomas

Comfort Suites Parkersburg South

Mineralwells

10/10 Excellent

kerenza

A hotel room with a large bed, a sofa, a desk with a computer, and a television.

Baymont by Wyndham Marietta

Marietta

10/10 Excellent

Nice hotel, easy to find next to Interstate 77, friendly staff. Got checked in and clerk suggested a local restaurant. Looks like they are still doing some remodeling, ceiling tiles and some wires hanging down. No funny smells in the hall or room either. Didn't get to the breakfast but did look in. Same as the photo. CLEAN room, non-smoking, no bed bugs. Microwave and refrigerator works. Not sure if the A/C wasn't quite up to speed but then the room never got hot either. Room was facing...

Anonymous traveler

Frequently Asked Questions

Can I find a vacation rental in Cairo?

Yes, we have vacation rentals near top attractions in Cairo, or you can choose a more remote option if you want a relaxing place to stay. Cairo is known for its restaurants and shopping. Make sure you have time to check out the parks while you're in the area.

What's the top vacation rental that Cairo has to offer?

Player Piano - Gym - Victorian - 4 Bed: This vacation home rental near Cairo offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What’s there to see and do in Cairo?

While you're exploring the area, North Bend State Park and Mountwood Park are a couple of picturesque spots to get outside and enjoy nature. Jones Cabin Run Vineyards and Woodridge Golf Club are a couple of places you'll find in the larger area.

What’s a vacation rental in Cairo like?

Vacation rentals are privately owned properties you can stay in for short or long periods in Cairo. Vacation rentals provide amenities such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for small groups.

Cairo Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Cairo vacation rentals

1. Quaint 1-bedroom tiny home with loft bed in charming Parkersburg

2. Cozy 1-bedroom tiny house in beautiful Parkersburg,WV

3. Charming Ranch + Renovated + Convenient Location

4. Shopping District Apt | Heart of Historic Downtown

5. Downtown Marietta Retreat

6. Captain's Quarters | One Bed Condo Waterfront on Ohio River

7. Hillside Hideaway in Marietta, OH: 4 beds, 2 baths, stunning views!

8. The Flat on Front Street

9. River Port | 3 Bed Condo Waterfront on Ohio River

10. The Historic Buckley House - 4 En-Suites - Walk Downtown

11. Close to everything in Marietta, OH- "Our Cozy Corner"

12. Dock Side | 2 Bed Condo Waterfront on Ohio River

13. Harbor Master | 2 Bed Condo Waterfront on Ohio River

Find vacation rentals that suit your style

Top Cairo Hotel Reviews

Fairfield Inn & Suites Marietta

10/10 Excellent

Frequently Asked Questions

Can I find a vacation rental in Cairo?

What's the top vacation rental that Cairo has to offer?

What’s there to see and do in Cairo?

What’s a vacation rental in Cairo like?