An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

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Our top choices for San Antonio hotels

1. Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (255 reviews)
"Great hotel. Will stay again next time I am in town."
Canada
Sean
The price is AED 422
AED 422 total
1 Dec - 2 Dec
Alko Hotel Casa Nispero

2. San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (72 reviews)
"Great place to explore the city culture."
United States
Yenny
The price is AED 285
AED 285 total
20 Nov - 21 Nov
San Antonio Hotel Boutique

3. Hotel habitat san antonio

Hotel habitat san antonio
San Antonio
10.0 out of 10, Exceptional, (1 review)
"Personal muy servicial y atenta"
Colombia
Giovanny
The price is AED 177
AED 177 total
20 Nov - 21 Nov
Hotel habitat san antonio

4. Viajero Cali Hostel & Salsa School

Viajero Cali Hostel & Salsa School
2.0 star property
San Antonio
9.0 out of 10, Wonderful, (70 reviews)
"Excellent stay. I stayed in a private room which was small, basic but comfortable. The staff were friendly. The hostel is in a excellent location close to restaurants, bars and attractions. The extra activities and the salsa school were amazing."
Australia
Jasmine
The price is AED 177
AED 177 total
16 Nov - 17 Nov
Viajero Cali Hostel & Salsa School

5. Our Home San Antonio

Our Home San Antonio
2.5 star property
San Antonio
10.0 out of 10, Exceptional, (1 review)
"Super friendly staff. Good food. Great frozen coffee. Nice location, closed to major city attractions."
United States
gloria
The price is AED 93
AED 148 total
16 Nov - 17 Nov
Our Home San Antonio

6. Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
9.4 out of 10, Exceptional, (6 reviews)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is AED 143
AED 143 total
17 Nov - 18 Nov
Hotel Casa Bresse

7. Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
10.0 out of 10, Exceptional, (1 review)
"Me gustó todo, muy bien ambiente, excelente trato, muy limpio....."
Mexico
David Alejandro
The price is AED 86
AED 86 total
22 Nov - 23 Nov
Epifania Guest House

8. casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
4.0 out of 10, (2 reviews)
"Cheap and convenient location. But mosquitoes in room every night and leaky toilet. There are better options available. "
Australia
Meyer
The price is AED 92
AED 92 total
19 Nov - 20 Nov
casa hostal ave maria san antonio cali

9. hotel boutique casa vecchia

hotel boutique casa vecchia
3.0 star property
San Cayetano, 0.4 km from San Antonio
10.0 out of 10, Exceptional, (1 review)
"Todo super bien, buena ubicación"
Colombia
carolina
The price is AED 145
AED 145 total
9 Dec - 10 Dec
hotel boutique casa vecchia

10. Hotel Dann Carlton Cali

Hotel Dann Carlton Cali
3.5 star property
El Peñon, 0.4 km from San Antonio
8.8 out of 10, Excellent, (493 reviews)
"Had a great stay at Dann Carlton Cali, great staff and accommodations!"
United States
Fabian
The price is AED 317
AED 317 total
22 Nov - 23 Nov
Hotel Dann Carlton Cali

11. Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels
4.0 star property
El Peñon, 0.4 km from San Antonio
9.0 out of 10, Wonderful, (489 reviews)
"Place was great. Location great many restaurant options around. Safe to walk around and close to major highlights like la calle del sabor, boulevard del rio, las trompetas, etc"
United States
Johana
The price is AED 161
AED 161 total
14 Dec - 15 Dec
Hotel el Peñón By Bithotels

12. InterContinental Cali by IHG

InterContinental Cali by IHG
4.0 star property
El Peñon, 0.3 km from San Antonio
9.0 out of 10, Wonderful, (1,000 reviews)
"Very clean, excellent service."
United States
Doris
The price is AED 573
AED 573 total
13 Dec - 14 Dec
InterContinental Cali by IHG

13. Hotel Casa Murano JLS

Hotel Casa Murano JLS
2.0 star property
La Merced, 0.5 km from San Antonio
10.0 out of 10, Exceptional, (1 review)
"Muy amable atenncion"
United States
YUDY ANDREA
The price is AED 159
AED 159 total
17 Nov - 18 Nov
Hotel Casa Murano JLS

14. Faranda Collection Cali, a member of Radisson Individuals

Faranda Collection Cali, a member of Radisson Individuals
4.0 star property
La Merced, 0.6 km from San Antonio
9.0 out of 10, Wonderful, (163 reviews)
"breakfast excellent the staff really friendly love everything about the hotel pillows comfy and white bed sheets really nice love it"
United States
siunly
The price is AED 347
AED 347 total
16 Nov - 17 Nov
Faranda Collection Cali, a member of Radisson Individuals

15. NH Boulevard Del Río Cali

NH Boulevard Del Río Cali
3.5 star property
Centenario, 0.7 km from San Antonio
9.0 out of 10, Wonderful, (389 reviews)
"Good location and staff is very helpful."
United States
David
The price is AED 268
AED 268 total
14 Dec - 15 Dec
NH Boulevard Del Río Cali

16. Hotel Stein Colonial

Hotel Stein Colonial
3.0 star property
Juanambú, 0.6 km from San Antonio
9.4 out of 10, Exceptional, (278 reviews)
"Great Hotel"
United States
Andres
The price is AED 192
AED 192 total
22 Nov - 23 Nov
Hotel Stein Colonial

17. Now Hotel Cali - Adults Only

Now Hotel Cali - Adults Only
4.0 star property
Juanambú, 1.1 km from San Antonio
8.8 out of 10, Excellent, (517 reviews)
"Great location, staff was respectful and open to help"
United States
Carlos
The price is AED 298
AED 298 total
16 Nov - 17 Nov
Now Hotel Cali - Adults Only

18. Hotel Foresto 365

Hotel Foresto 365
4.0 star property
El Peñon, 0.5 km from San Antonio
9.6 out of 10, Exceptional, (73 reviews)
"I Definitely recommend it"
United States
Juan
The price is AED 244
AED 244 total
22 Nov - 23 Nov
Hotel Foresto 365

19. Altio hotel

Altio hotel
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (205 reviews)
"It was a really nice stay, and In a very convenient location!"
United States
Manuel
The price is AED 177
AED 177 total
17 Nov - 18 Nov
Altio hotel

20. Hotel Dann Cali

Hotel Dann Cali
3.0 star property
El Peñon, 0.4 km from San Antonio
8.6 out of 10, Excellent, (622 reviews)
"Nice hotel, nice buffet, excellent location and friendly staff, definitely I'll come back"
United States
Holmes
The price is AED 243
AED 243 total
6 Dec - 7 Dec
Hotel Dann Cali
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in San Antonio

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
An outdoor patio with a glass table and chairs, surrounded by lush greenery and illuminated by green lighting.
Alko Hotel Casa Nispero
4.0 star property
9.4
Exceptional
255 reviews
View
A courtyard with a wooden table and chairs, surrounded by potted plants and a climbing plant wall.
Hotel Casa Bresse
2.5 star property
9.4
Exceptional
6 reviews
View
A spacious lobby with a central fountain, multiple artworks, and a reception desk.
San Antonio Hotel Boutique
3.0 star property
9.2
Wonderful
72 reviews
View
An indoor dining area with tables and chairs, surrounded by hanging plants and greenery.
Viajero Cali Hostel & Salsa School
2.0 star property
9.0
Wonderful
70 reviews
View
An outdoor cafe area with tables and chairs, surrounded by potted plants and a covered seating area.
Our Home San Antonio
2.5 star property
10.0
Exceptional
1 review
View

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

El Peñon

When in El Peñon, you can plan a visit to Gato de Tejada Monument and Calima Gold Museum of the Bank of the Republic, some noteworthy sights in the nearby area.

Pance

Pance might not have many top sights, but Chorrera del Indio and Los Arrayanes Recreational Center are two attractions nearby that you can check out.

Top San Antonio Hotel Reviews

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Another good option for your stay in the area is Viajero Cali Hostel & Salsa School.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.