An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

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30 Oct - 1 Nov
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6 Nov - 8 Nov

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Our top choices for San Antonio hotels

A spiral staircase in a courtyard surrounded by lush greenery and concrete structures.

1. Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (250 reviews)
"Excellent. Location, location, location...the best"
United States
ALVARO
The price is AED 563
AED 563 total
28 Oct - 29 Oct
Alko Hotel Casa Nispero
A spacious lobby with a central fountain, multiple artworks, and a reception desk.

2. San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (70 reviews)
"The location was excellent, within close distance to many good restaurants. The breakfast was good, with fruit and made to order eggs. The AC was quite adequate. "
United States
Jung
The price is AED 263
AED 333 total
4 Nov - 5 Nov
San Antonio Hotel Boutique
A statue of a seated figure with a candle and a decorative box in a modern lobby with a reception desk and a potted plant.

3. Hotel habitat san antonio

Hotel habitat san antonio
San Antonio
10.0 out of 10, Exceptional, (1 review)
"Personal muy servicial y atenta"
Colombia
Giovanny
The price is AED 187
AED 187 total
3 Nov - 4 Nov
Hotel habitat san antonio
Pool

4. Viajero Cali Hostel & Salsa School

Viajero Cali Hostel & Salsa School
2.0 star property
San Antonio
9.0 out of 10, Wonderful, (70 reviews)
"Excellent stay. I stayed in a private room which was small, basic but comfortable. The staff were friendly. The hostel is in a excellent location close to restaurants, bars and attractions. The extra activities and the salsa school were amazing."
Australia
Jasmine
The price is AED 190
AED 190 total
26 Oct - 27 Oct
Viajero Cali Hostel & Salsa School
A courtyard with a wooden table and chairs, surrounded by potted plants and a climbing plant wall.

5. Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
9.2 out of 10, Wonderful, (5 reviews)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is AED 174
AED 174 total
25 Oct - 26 Oct
Hotel Casa Bresse
A hotel room with a bed, a chair, a bedside table with a lamp, and a window.

6. Our Home San Antonio

Our Home San Antonio
2.5 star property
San Antonio
10.0 out of 10, Exceptional, (1 review)
"Super friendly staff. Good food. Great frozen coffee. Nice location, closed to major city attractions."
United States
gloria
The price is AED 119
AED 178 total
17 Nov - 18 Nov
Our Home San Antonio
A modern kitchen with a central island, two wicker bar stools, a red pendant light, and a large window with a view.

7. Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
10.0 out of 10, Exceptional, (1 review)
"Me gustó todo, muy bien ambiente, excelente trato, muy limpio....."
Mexico
David Alejandro
The price is AED 82
AED 82 total
6 Nov - 7 Nov
Epifania Guest House
A stone fountain with a child statue, surrounded by potted plants and a tiled wall with a window and a framed picture.

8. casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
4.0 out of 10, (2 reviews)
"Cheap and convenient location. But mosquitoes in room every night and leaky toilet. There are better options available. "
Australia
Meyer
The price is AED 54
AED 54 total
25 Oct - 26 Oct
casa hostal ave maria san antonio cali
A swimming pool with a tiled deck, a dining area with chairs and a table, and a wall decorated with posters.

9. hotel boutique casa vecchia

hotel boutique casa vecchia
3.0 star property
San Cayetano, 0.4 km from San Antonio
10.0 out of 10, Exceptional, (1 review)
"Todo super bien, buena ubicación"
Colombia
carolina
The price is AED 157
AED 157 total
1 Nov - 2 Nov
hotel boutique casa vecchia
A hotel with a modern facade, a prominent sign, and a landscaped entrance area.

10. InterContinental Cali by IHG

InterContinental Cali by IHG
4.0 star property
El Peñon, 0.3 km from San Antonio
9.0 out of 10, Wonderful, (1,000 reviews)
"Very good hotel and staff"
United States
Pedro
The price is AED 573
AED 573 total
21 Nov - 22 Nov
InterContinental Cali by IHG
A modern living room with a hammock, a large potted plant, a sofa, and a coffee table.

11. Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels
4.0 star property
El Peñon, 0.4 km from San Antonio
9.0 out of 10, Wonderful, (483 reviews)
"Great hotel, centrally located"
Australia
ross
The price is AED 215
AED 215 total
24 Nov - 25 Nov
Hotel el Peñón By Bithotels
A bedroom with a large bed, two nightstands, and a wall-mounted painting of a cat.

12. Hotel Casa Murano JLS

Hotel Casa Murano JLS
2.0 star property
La Merced, 0.5 km from San Antonio
The price is AED 166
AED 166 total
25 Oct - 26 Oct
Hotel Casa Murano JLS
A historic building with a central courtyard, stone steps, and a traditional balcony.

13. Hotel Stein Colonial

Hotel Stein Colonial
3.0 star property
Juanambú, 0.6 km from San Antonio
9.4 out of 10, Exceptional, (275 reviews)
"Super friendly staff, beautiful historic hotel, & great location/breakfast!"
United States
kevin
The price is AED 203
AED 203 total
25 Oct - 26 Oct
Hotel Stein Colonial
A hotel lobby with a grand chandelier, seating area, and a decorative plant centerpiece.

14. Hotel Dann Carlton Cali

Hotel Dann Carlton Cali
3.5 star property
El Peñon, 0.4 km from San Antonio
8.8 out of 10, Excellent, (488 reviews)
"the best place to stay in Cali"
United States
Sarah
The price is AED 373
AED 373 total
8 Nov - 9 Nov
Hotel Dann Carlton Cali
A rooftop pool with a tiled edge, a sign indicating a Jacuzzi, and a view of a cityscape with buildings and hills in the background.

15. Faranda Collection Cali, a member of Radisson Individuals

Faranda Collection Cali, a member of Radisson Individuals
4.0 star property
La Merced, 0.6 km from San Antonio
9.0 out of 10, Wonderful, (160 reviews)
"Great hotel and staff. Perfect location"
United States
Nicholas
The price is AED 367
AED 367 total
25 Oct - 26 Oct
Faranda Collection Cali, a member of Radisson Individuals
A hotel with a modern facade, outdoor seating area, and vertical gardens.

16. Hotel Foresto 365

Hotel Foresto 365
4.0 star property
El Peñon, 0.5 km from San Antonio
9.6 out of 10, Exceptional, (71 reviews)
"Staff was super friendly."
United Kingdom
Axel
The price is AED 223
AED 223 total
26 Oct - 27 Oct
Hotel Foresto 365
A hotel room with two beds, a TV, a desk, and a bathroom.

17. Hotel Centro

Hotel Centro
2.0 star property
0.8 km from San Antonio
The price is AED 143
AED 143 total
3 Nov - 4 Nov
Hotel Centro
A spacious lobby with a beige sofa, a chandelier, and a reception desk.

18. Hotel Obelisco

Hotel Obelisco
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (556 reviews)
"Great customer service, very clean and good food"
United States
James
The price is AED 295
AED 295 total
24 Nov - 25 Nov
Hotel Obelisco
A dining area with wooden chairs and tables, a central plant, and wall-mounted lights.

19. NH Boulevard Del Río Cali

NH Boulevard Del Río Cali
3.5 star property
Centenario, 0.7 km from San Antonio
9.0 out of 10, Wonderful, (389 reviews)
"Constable bed, dark and quiet room, the staff was very nice and always willing to help."
United States
Regis
The price is AED 307
AED 307 total
2 Nov - 3 Nov
NH Boulevard Del Río Cali
A building with red and white exterior walls, a tiled roof, and a brick-paved entrance.

20. Laundry House

Laundry House
2.0 star property
El Peñon, 0.3 km from San Antonio
The price is AED 68
AED 68 total
25 Oct - 26 Oct
Laundry House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.
A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

When in El Peñon, you can plan a visit to Gato de Tejada Monument and Calima Gold Museum of the Bank of the Republic, some noteworthy sights in the nearby area.

Pance

Pance might not have many top sights, but Chorrera del Indio and Los Arrayanes Recreational Center are two attractions nearby that you can check out.

Top San Antonio Hotel Reviews

Hotel Dann Cali

Hotel Dann Cali

10/10 Excellent
"Excellent"
Daniel 1-night trip
Posted 2 hours ago
Hotel Dann Cali

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Another good option for your stay in the area is Viajero Cali Hostel & Salsa School.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.