A calm body of water, a sandy beach, and a forested area in the distance.

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Check prices for these dates

In two weeks
14 Aug - 16 Aug
In two months
25 Sep - 27 Sep
In three months
23 Oct - 25 Oct
In four months
20 Nov - 22 Nov

Our top choices for Cape Girardeau vacation homes

Living area

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
3 Aug - 4 Aug
Little Blue Cottage on Spanish
Exterior

2. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (42 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AED 658
AED 1,161 total
includes taxes & fees
5 Aug - 6 Aug
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Pool

3. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is AED 1,240
AED 2,035 total
includes taxes & fees
5 Aug - 6 Aug
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Coffee/tea maker, fridge, microwave, dishwasher

4. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
Beautifully Renovated Farmhouse in Jackson, MO
Smart TV

5. Rent All 5 Suites at Peach Tree Inn

Rent All 5 Suites at Peach Tree Inn
Cobden
The price is AED 2,436
AED 2,853 total
includes taxes & fees
31 Aug - 1 Sep
Rent All 5 Suites at Peach Tree Inn
Exterior

6. Crossview Cottage - Has a direct view of the Bald Knob Cross Monument

Crossview Cottage - Has a direct view of the Bald Knob Cross Monument
Alto Pass
The price is AED 422
AED 934 total
includes taxes & fees
3 Aug - 4 Aug
Crossview Cottage - Has a direct view of the Bald Knob Cross Monument
Exterior

7. Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
9.8 out of 10, Exceptional, (16 reviews)
"Lovely time, easy for our dog and for our family, did the tarot card reading that was recommended by host and it did not disappoint!"
United States
Elizabeth W.
The price is AED 652
AED 1,280 total
includes taxes & fees
3 Aug - 4 Aug
Magical Victorian near hiking / wine trail
Exterior detail

8. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (10 reviews)
"Cool renovated property that keeps that old fashioned charm. Spacious living with all the amenities you need for a vacation stay."
United States
Dylan
The price is AED 505
AED 1,057 total
includes taxes & fees
4 Aug - 5 Aug
Stunning 2 bedroom in town, close to Shawnee National Forest
Outdoor dining

9. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Alto Pass
10.0 out of 10, Exceptional, (4 reviews)
"The house was very welcoming and clean. Very inviting for our short stay. "
United States
brian O.
The price is AED 643
AED 960 total
includes taxes & fees
3 Aug - 4 Aug
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Outdoor dining

10. Rendelman Orchard's Farm Stay

Rendelman Orchard's Farm Stay
Alto Pass
9.8 out of 10, Exceptional, (14 reviews)
"The chickens and yard were absolutely amazing- wish we had more time to enjoy and explore the grounds! Our host was very nice and communicative. We loved the two wineries near by. There were some bugs inside when we checked in and throughout the evening but that’s to be expected on the farm. Appreciated the fly swatter and the light traps! Highly recommend this stay."
United States
Kayla F.
The price is AED 692
AED 828 total
includes taxes & fees
3 Aug - 4 Aug
Rendelman Orchard's Farm Stay
Interior

11. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (22 reviews)
"Nice little house that was perfect for our family of five plus our dog. We would stay here again if we found ourselves out this way again."
United States
Kyle
The price is AED 327
AED 580 total
includes taxes & fees
4 Aug - 5 Aug
Cozy and Updated Farmhouse with King Suite
Living area

12. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Anna
10.0 out of 10, Exceptional, (7 reviews)
"We greatly enjoyed our stay at this property. The communication and hospitality from the host was top notch. The property is beautiful and well maintained. The house was incredibly clean, well furnished, and cozy. Our family loved the rural setting and close proximity to the neighboring towns. Incredible value for all the amenities and features you get. We will definitely be back!"
United States
Aaron D.
The price is AED 572
AED 1,139 total
includes taxes & fees
14 Aug - 15 Aug
Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Exterior

13. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is AED 367
AED 641 total
includes taxes & fees
18 Aug - 19 Aug
The Weber Farm - Enjoy a beautiful 100 acre farm!
Outdoor dining

14. Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
9.8 out of 10, Exceptional, (79 reviews)
"We had a great stay! Secluded cabin and a large property just the right size for a weekend away and within 20-30 minute driving distance of beautiful hiking trails/unique and delicious local restaurants! Would stay again. "
United States
Hanna S.
The price is AED 358
AED 652 total
includes taxes & fees
9 Aug - 10 Aug
Beautiful location in the secluded woods
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent
"The bed and sheets were sooo comfortable. Everything was very clean and looked brand new. I'll definitely stay again!"
Jessica 1-night trip
Posted 5 hours ago
Tru By Hilton Cape Girardeau