The Best Resorts & Hotels with Spas in Central San Diego, CA from AED 330 in 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Central San Diego hotels with a spa

A hotel with a curved entrance, palm trees, and a parking lot.

1. Handlery Hotel

Mission Valley

Surrender to spa treatments and poolside luxury at this hotel with massage rooms and a beautiful heated outdoor pool and hot tub.

AED 381 total

includes taxes & fees

1 Dec - 2 Dec

A modern bathroom with a shower, a towel rack, and a bench.

2. Legacy Resort Hotel & Spa

Mission Valley

Indulge in a serene escape at this upscale hotel with a full-service spa, outdoor pool with free cabanas, and couples massage treatments.

AED 684 total

includes taxes & fees

22 Nov - 23 Nov

A spa room with a bed, a bathtub, and a large window with curtains. There are candles and plants on the windowsill.

3. San Diego Mission Bay Resort

Mission Bay

Unwind at this bay-view resort offering garden massages, poolside lounging, and a rejuvenating full-service spa retreat.

AED 992 total

includes taxes & fees

29 Nov - 30 Nov

A modern building with a sloped roof and large windows, surrounded by palm trees and a well-maintained garden.

4. Best Western Plus Island Palms Hotel & Marina

Point Loma

Blissful bay views and relaxing massages set the scene for a restorative escape at this waterfront sanctuary with bubbling hot tubs.

AED 589 total

includes taxes & fees

13 Dec - 14 Dec

A spacious lobby with a marble reception desk, comfortable seating, and potted plants.

5. Pacific Terrace Hotel

Pacific Beach

Escape to a beachfront wellness sanctuary with heated pool, private spa services, and ocean-view hot tub for a serene coastal retreat.

AED 933 total

includes taxes & fees

29 Nov - 30 Nov

A spacious lobby with a reception desk, seating area, and artwork on the walls.

6. Hyatt Regency Mission Bay Spa and Marina

Mission Bay

Experience coastal tranquility at this spa hotel with bay views, heated pools, and waterslides.

AED 905 total

includes taxes & fees

1 Dec - 2 Dec

A couple seated under a floral arch with a city skyline in the background.

7. Coronado Island Marriott Resort & Spa

Bayside

Unwind in a serene waterfront escape featuring 10 spa treatment rooms, 3 outdoor pools, and private balconies with stunning bay views.

AED 1,251 total

includes taxes & fees

1 Dec - 2 Dec

A person sitting by a pool with a tiled floor and a marble wall.

8. Sycuan Casino Resort

El Cajon

Escape to a luxurious mountain retreat with 10 treatment rooms and outdoor pools, where hot stone massages and aromatherapy await.

AED 408 total

includes taxes & fees

14 Dec - 15 Dec

An aerial view of a resort with a central swimming pool, palm trees, and a view of the ocean and beach.

9. Paradise Point Resort & Spa

Mission Bay

Immerse in waterfront tranquility with hot stone massages and aromatherapy at this resort spa retreat.

AED 1,035 total

includes taxes & fees

13 Dec - 14 Dec

A hallway with a wooden ceiling, a potted plant, a sofa with orange cushions, and a fireplace.

10. Pantai Inn

Village of La Jolla

Oceanfront wellness sanctuary provides calming massage therapies and a garden terrace, perfect for unwinding after a day by La Jolla Cove.

AED 1,517 total

includes taxes & fees

11 Dec - 12 Dec

View all properties

Choose what matters most at spa hotels in Central San Diego

Pool

Breakfast included

Top Central San Diego Hotel Reviews

Legacy Resort Hotel & Spa

Mission Valley

10/10 Excellent

Sirma

Pacific Terrace Hotel

Pacific Beach

10/10 Excellent

David

San Diego Mission Bay Resort

Mission Bay

10/10 Excellent

Based on some negative reviews, I started to change hotels, I’m glad that I didn’t. This property is amazing!!! It was very clean. The outside of the buildings could use a good power wash, otherwise everything else was immaculate. Staying within the Mission Bay Park area was a non-issue. We didn’t have any problems with the general public or homeless in the park. Also, while the bay area near the resort is not all that beautiful (in my opinion), the water is clear and swim friendly. It’s a nice...

Donita

Pantai Inn

Village of La Jolla

10/10 Excellent

My wife and I just spent 3 nights here for our Anniversary. The view from the living room and balcony was incredible. When we arrived our keys and paperwork were ready for us. we spent about 1 minute in the lobby signing in and receiving our keys before they took us on a quick tour to show us around the property and then escorted us to the room. The room was stocked with a variety of snacks and drinks. The snacks were simple single serve items like pretzels, cookies, chips and granola bars....

John

A woman in a floral swimsuit stepping out of a spa area with a hot tub, a lounge chair, and a sign indicating an outdoor terrace.

Fairmont Grand Del Mar

Carmel Valley

10/10 Excellent

My wife, 2 year old, and 6 month old stayed at this hotel for 3 nights (buy 2 nights get one free). Upon check in I asked if there were any available upgrades. After checking, they gave us a free upgrade with an amazing view. The entire time we were there the staff was extremely nice. They gave my kids toys on three separate occasions. There are 2 toddler pools and there are lounge areas where the kids can play in the sand (a mock beach). As soon as we sat in the sand area the staff came...

Daniel

A spacious restaurant with high ceilings, exposed beams, and hanging plants. There are multiple seating areas with tables and chairs.

Best Western Plus Marina Gateway Hotel

National City

10/10 Excellent

Robert

Best Western Plus Island Palms Hotel & Marina

Point Loma

10/10 Excellent

Taylor

A spacious lobby with a reception desk, seating area, and a stone wall.

Humphreys Half Moon Inn

Point Loma

10/10 Excellent

Kailey

Coronado Island Marriott Resort & Spa

Bayside

10/10 Excellent

Elaine

Hyatt Regency Mission Bay Spa and Marina

Mission Bay

10/10 Excellent

Jose

A modern bathroom with a shower, a towel rack, and a tray with toiletries.

The Lodge at Torrey Pines

Torrey Pines

10/10 Excellent

Jason

A reception area with a wooden reception desk, a potted plant, and a sofa with cushions.

Westgate Hotel

Downtown San Diego

10/10 Excellent

Alfredo

A spa room with two massage tables, a stone wall, a wooden cabinet with towels, and wall-mounted lights.

Hotel Indigo San Diego Del Mar by IHG

Del Mar

10/10 Excellent

We stayed here for 2 nights and loved the experience! The staff was really friendly and accommodated an early check-in request which was big time as we had a maintenance project going on at our apartment. We brought our cat and paid the pet fee. The staff was really nice to our cat and gave her attention at check-in and check-out :D We paid a bit more to get the bigger room option, and that was well worth it. The room was comfy with a couch, king bed, additional seating, desk, etc....

Josh