Find Resorts & Hotels with Spas in Clemson, SC

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Check prices for these dates

Tonight
5 Nov - 6 Nov
Tomorrow
6 Nov - 7 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov
No exact matches found, but these alternatives could be just right

Recommended hotels in Clemson

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

1. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (907 reviews)
The price is AED 768
AED 852 total
includes taxes & fees
8 Nov - 9 Nov
The Shepherd Hotel Downtown Clemson
A hotel breakfast area with seating and a counter.

2. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (999 reviews)
The price is AED 474
AED 526 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Clemson by IHG
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

3. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (658 reviews)
The price is AED 526
AED 583 total
includes taxes & fees
25 Nov - 26 Nov
The Abernathy of Clemson
A modern bar area with a menu board, bar stools, and a countertop with various items.

4. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (595 reviews)
The price is AED 379
AED 421 total
includes taxes & fees
22 Nov - 23 Nov
Courtyard Marriott Clemson
A golf course with a water body, trees, and a distant view of a bridge.

5. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (1,005 reviews)
The price is AED 511
AED 567 total
includes taxes & fees
30 Nov - 1 Dec
Clemson University's James F. Martin Inn
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

6. Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very good, (1,004 reviews)
The price is AED 277
AED 307 total
includes taxes & fees
8 Nov - 9 Nov
Inn @ Clemson
A modern bathroom with a large mirror, a vanity with a sink, and a glass shower enclosure.

7. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.4 out of 10, Very good, (1,003 reviews)
The price is AED 372
AED 412 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn & Suites Clemson - University Area
A spacious hallway with a patterned carpet, a sofa with cushions, a coffee table, and framed artwork on the walls.

8. The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (938 reviews)
The price is AED 547
AED 608 total
includes taxes & fees
8 Nov - 9 Nov
The Inn at Patrick Square
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

9. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.0 out of 10, Very good, (1,001 reviews)
The price is AED 372
AED 412 total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Clemson Hotel & Conference Center
A modern kitchen area with a bar counter and seating.

10. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (654 reviews)
The price is AED 403
AED 447 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Clemson-University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Clemson

Pool
Breakfast included

Top Clemson Hotel Reviews

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson

10/10 Excellent

We had an amazing stay. From the beautifully decorated, relaxing room, to the restaurant decor and excellent service and food, to the cute coffee stations on each floor, to the bar and deck, it was all fantastic!
United States
Amy
Reviewed July 14, 2025
The Shepherd Hotel Downtown Clemson

Frequently Asked Questions

Looking for a spa hotel in Clemson?

Treat yourself to some pampering and book a hotel with a spa. Check out the live music scene and local architecture in Clemson—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.

What is the best spa hotel in Clemson?

Days Inn by Wyndham Clemson

How many spa hotels will I find in Clemson?

Among Expedia's 83 accommodation options in Clemson, there is 1 spa hotel.

What's there to see and do in Clemson?

Enjoy all that Clemson has to offer when you visit Fort Hill, Memorial Stadium, and Littlejohn Coliseum. If you have extra time while you're in the area, you might want to stop by Brooks Center for the Performing Arts and South Carolina Botanical Gardens.

What is a Clemson spa hotel?

Spa hotels in Clemson provide lodging and have an on-site spa offering services like couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.