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1 Oct - 2 Oct
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2 Oct - 3 Oct
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2 Oct - 4 Oct
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9 Oct - 11 Oct

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Our top choices for Commerce hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Elizabeth
AED 264
AED 298 total
includes taxes & fees
11 Oct - 12 Oct
Pear Tree Inn Cape Girardeau West
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

2. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
AED 372
AED 419 total
includes taxes & fees
8 Oct - 9 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
AED 364
AED 414 total
includes taxes & fees
29 Oct - 30 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
AED 331
AED 373 total
includes taxes & fees
5 Oct - 6 Oct
Drury Inn & Suites Cape Girardeau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A hotel room with two beds, a nightstand, a lamp, and a chair.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

5. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
AED 297
AED 321 total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

6. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
AED 389
AED 438 total
includes taxes & fees
8 Oct - 9 Oct
Hampton Inn Cape Girardeau I 55 East
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

7. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
AED 367
AED 414 total
includes taxes & fees
5 Oct - 6 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

8. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
AED 386
AED 436 total
includes taxes & fees
4 Oct - 5 Oct
The Riverview
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
AED 328
AED 374 total
includes taxes & fees
8 Oct - 9 Oct
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel room with a bed, a TV, a desk, and a chair.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
AED 312
AED 372 total
includes taxes & fees
11 Oct - 12 Oct
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Danny
AED 219
AED 247 total
includes taxes & fees
1 Nov - 2 Nov
Quality Inn Cape Girardeau North
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.
A room with large windows, two red upholstered chairs, a small table, and a potted plant.

12. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
AED 278
AED 301 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Suites Jackson-Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A spacious living room with a sofa set, a coffee table, and a dining area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

13. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
AED 459
AED 521 total
includes taxes & fees
12 Oct - 13 Oct
Courtyard by Marriott Cape Girardeau Downtown
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

14. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott
AED 345
AED 397 total
includes taxes & fees
29 Oct - 30 Oct
Drury Inn & Suites Sikeston, MO
A building with a fountain and flower beds in front.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

15. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Kathleen
AED 244
AED 271 total
includes taxes & fees
3 Oct - 4 Oct
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

16. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
William
AED 219
AED 243 total
includes taxes & fees
4 Oct - 5 Oct
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel lobby with a reception desk, seating area, and a large window.
A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.
A hotel room with a desk, chair, television, and a lamp.
A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

17. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
United States
Santiago
AED 251
AED 278 total
includes taxes & fees
16 Oct - 17 Oct
Quality Inn Cairo I-57
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

18. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Joshua
AED 257
AED 300 total
includes taxes & fees
2 Oct - 3 Oct
Town House Inn Cape Giradreau
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A bathroom with a sink, mirror, towel rack, shower, and toilet.
A motel with a sign reading "Eagle Inn" and a parking lot with several cars.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

19. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
AED 242
AED 269 total
includes taxes & fees
2 Oct - 3 Oct
Eagle Inn Charleston
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A bathroom with a bathtub, toilet, and shower curtain.
A reception area with a counter, a coffee machine, and seating.

20. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
AED 207
AED 246 total
includes taxes & fees
4 Oct - 5 Oct
Country Yard Inn and Suite
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Top Commerce Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"EVERYONE was EXTREMELY FRIENDLY"
Rex 1-night trip
Posted 7 hours ago
Drury Inn & Suites Sikeston, MO
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"No complaints"
Don 3-night trip
Posted 13 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

10/10 Excellent
"Great place great breakfast great room staff was great"
Jim 1-night trip
Posted 19 hours ago
Quality Inn Cape Girardeau North
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"trodo estubo excelente gracias por sus servicios"
Julio 1-night trip
Posted 2 days ago
Candlewood Suites Cape Girardeau by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent
"Clean rooms. Nice breakfast. Very nice staff."
Teresa 1-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."
Christy 2-night trip
Posted 3 days ago
Drury Inn & Suites Cape Girardeau
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

8/10 Good
"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."
Valarie 2-night trip
Posted 3 days ago
Hampton Inn Cape Girardeau I 55 East
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent
"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."
Sheila and keith 1-night trip
Posted 5 days ago
Courtyard by Marriott Cape Girardeau Downtown
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

10/10 Excellent
"Super communication! . Accommodating. Nice people"
JASEN 2-night trip
Posted 2 weeks ago
Cozy cabins on beautiful Horseshoe Lake

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO
AED 219
AED 243 total
4 Oct - 5 Oct
includes taxes & fees
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
AED 219
AED 247 total
1 Nov - 2 Nov
includes taxes & fees
7/10 Good! (801 reviews)
Quality Inn Cape Girardeau North
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
AED 264
AED 298 total
11 Oct - 12 Oct
includes taxes & fees
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO
AED 312
AED 372 total
11 Oct - 12 Oct
includes taxes & fees
8/10 Very Good! (1,000 reviews)
Candlewood Suites Cape Girardeau by IHG
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO
AED 328
AED 374 total
8 Oct - 9 Oct
includes taxes & fees
Tru By Hilton Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
AED 364
AED 414 total
29 Oct - 30 Oct
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

What's the best place to stay in Commerce?
Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in Commerce.
What are some of the best vacation home rentals in Commerce?
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This vacation home rental near Commerce is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Commerce.
If I need to cancel my hotel reservation in Commerce, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.
Where can I learn more about changing or cancelling my trip to Commerce?
To find more details about rescheduling or cancelling your trip to Commerce, go to https://www.expedia.com/service/.
What's it like to stay in Commerce?
Travelers to Commerce will find plenty to explore and enjoy. There are 88 hotels and other accommodations in the surrounding area. Find out more about Commerce.
What is there to see in Commerce?
A favorite place to visit is Mississippi River. You'll also find Century Casino & Hotel Cape Girardeau and Show Me Center in the area. Check out what more to see and do in Expedia's Commerce guide.
What's the weather like in Commerce?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Commerce is 59 inches.