De Soto, WI Vacation Homes from AED 738

A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.

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Our top choices for De Soto vacation homes

A hot tub with a wooden deck and a table with a bottle and flowers.

1. Room on the Ridge / HOT TUB / Sleeps 2

Wheatland

scott o.

AED 738 total

includes taxes & fees

1 Nov - 2 Nov

2. Butterfly Bend / HOT TUB / Sleeps 4

Wheatland

Danielle Y.

AED 1,260 total

includes taxes & fees

12 Oct - 13 Oct

A cozy kitchen with wooden walls, a central island with stools, and a large window.

3. Barn On The Ridge / HOT TUB / Sleeps 6

Wheatland

Katelyn

AED 1,534 total

includes taxes & fees

12 Oct - 13 Oct

A hot tub under a wooden pergola with a view of the countryside.

4. The Quarry / HOT TUB / Sleeps 5

Wheatland

Vickie D.

AED 1,135 total

includes taxes & fees

8 Nov - 9 Nov

A neatly arranged bedroom with a large bed, two bedside tables, a nightstand, a wall clock, and a framed quote.

5. Enjoy the top floor of this victorian house With two suites & a bonus bedroom

Lansing

Daira H.

AED 987 total

includes taxes & fees

11 Oct - 12 Oct

A spacious living room with a large sofa, a coffee table, and a view of a snowy landscape through large windows.

6. Copper Creek Getaway Sleeps 6 Hot Tub

Seneca

Cindy B.

AED 1,444 total

includes taxes & fees

21 Oct - 22 Oct

A kitchen with a black stovetop, a microwave above it, and a tiled backsplash.

7. 4BR Retreat in Waukon • Group Friendly

Waukon

Sue B.

AED 835 total

includes taxes & fees

8 Nov - 9 Nov

A spacious living area with a wooden floor, a curved staircase, a sofa set, and large windows offering a view.

8. Garden Ridge Retreat- Farm Stay

Viroqua

Pat B.

A rustic cabin with a stone facade, wooden deck, and a large porch.

9. Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

Eastman

Brooke N.

AED 1,225 total

includes taxes & fees

22 Oct - 23 Oct

A spacious living area with a wooden floor, a dining table with chairs, a sofa, and a television.

10. Blakley Hobbit Charming 2-bedroom country house with AC, WiFi in soothing Viola

Viola

Joseph W.

AED 1,151 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor deck with a table and four chairs, overlooking a body of water and surrounded by bare trees.

11. Riverfront Twin Home

La Crosse

Jack H.

A modern living room with a staircase, a dark door, a grey armchair, and a coffee table with decorative items.

12. The Honey Haven

Westby

Eric R.

AED 922 total

includes taxes & fees

20 Oct - 21 Oct

A modern bar area with a large flat-screen TV displaying a beach scene, wooden cabinets, neon signs, and comfortable seating.

13. Campus-Area 4BR | Panoramic Bluffs

Holy Trinity-Longfellow

Kim M.

A cozy living room with a wooden ceiling, a grey sofa, and a view through a glass door to an outdoor patio.

14. Secluded Rustic Cabin

Cashton

Becky K.

AED 1,839 total

includes taxes & fees

11 Oct - 12 Oct

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Top De Soto Hotel Reviews

Gundersen Hotel & Suites

8/10 Good

"We had a very clean room. The bed was very comfortable, and the pillows were awesome. Would definitely stay here again in the future!"

Log Cabin next to the Mississippi River

10/10 Excellent

"I just loved the nostalgic somewhat western way it was decorated. I've stayed in many condos since 2002. None even came close to being to having all the utensils etc as this one. On top of that there were other things you would never expect like sandwich bags sugar ice in the ice trays and on and on. Very unique setting outside- you'd have to see it to know its like noother."

Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

8/10 Good

"Honestly wasn't my choice in cabins, an hour SW of where I was looking. Other VRBOs were snatched up within a few hours (8 to be exact) so I was desperate for a spot for my family with two young adult children. Both recliners were broken, not able to to use for a single sleeping arrangement. There is no stove and the toaster oven was broken but still out on the small kitchenette counter. We made do but my son slept poorly on wide defunct recliner. Host was nice and personable. Probably won't return for various reasons."

AmericInn by Wyndham Viroqua

8/10 Good

"The staff go above and beyond. Great customer service. The young gal at the front desk is very good and has excellent customer service. My only disappointment was there was no drinking water, unless you wanted to pay for it out of the machine. I truly believe I spent more than enough money for 2 nights of stay that I should not have had to pay for water."

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Soldiers Grove Vacations

Room 1

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Our top choices for De Soto vacation homes

1. Room on the Ridge / HOT TUB / Sleeps 2

2. Butterfly Bend / HOT TUB / Sleeps 4

3. Barn On The Ridge / HOT TUB / Sleeps 6

4. The Quarry / HOT TUB / Sleeps 5

5. Enjoy the top floor of this victorian house With two suites & a bonus bedroom

6. Copper Creek Getaway Sleeps 6 Hot Tub

7. 4BR Retreat in Waukon • Group Friendly

8. Garden Ridge Retreat- Farm Stay

9. Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

10. Blakley Hobbit Charming 2-bedroom country house with AC, WiFi in soothing Viola

11. Riverfront Twin Home

12. The Honey Haven

13. Campus-Area 4BR | Panoramic Bluffs

14. Secluded Rustic Cabin

Find vacation rentals that suit your style

Top De Soto Hotel Reviews

Gundersen Hotel & Suites

Boarders Inn & Suites by Cobblestone Hotels – Waukon

Cozy Secluded Cabin w/ Hot Tub, Relax, Unwind & Stargaze

Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Log Cabin next to the Mississippi River

Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

Scenic Valley Motel

AmericInn by Wyndham Viroqua

Mississippi Cabin with Boat dock

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Search Vacation Homes in De Soto

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for De Soto vacation homes

1. Room on the Ridge / HOT TUB / Sleeps 2

2. Butterfly Bend / HOT TUB / Sleeps 4

3. Barn On The Ridge / HOT TUB / Sleeps 6

4. The Quarry / HOT TUB / Sleeps 5

5. Enjoy the top floor of this victorian house With two suites & a bonus bedroom

6. Copper Creek Getaway Sleeps 6 Hot Tub

7. 4BR Retreat in Waukon • Group Friendly

8. Garden Ridge Retreat- Farm Stay

9. Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

10. Blakley Hobbit Charming 2-bedroom country house with AC, WiFi in soothing Viola

11. Riverfront Twin Home

12. The Honey Haven

13. Campus-Area 4BR | Panoramic Bluffs

14. Secluded Rustic Cabin

Find vacation rentals that suit your style

Top De Soto Hotel Reviews

Gundersen Hotel & Suites

Explore a world of travel with Expedia