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Compare 93 Vacation Homes in De Soto with updated reviews, rates, and availability.

Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

9.8 out of 10, Exceptional, (483)
"This was a great place to go and get away from the computers and normal day hustle and bustle of life, and spend quality time with the wife. Would definitely stay here again."
Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Riverfront Twin Home

10.0 out of 10, Exceptional, (26)
"Nice place to stay. Great location. "
The price is AED 496
AED 1,136 total
includes taxes & fees
8 Jun - 9 Jun
Riverfront Twin Home

Country home-just steps from Coon Creek and a short drive to Mississippi River

10.0 out of 10, Exceptional, (25)
"This was a great place to stay while enjoying a weekend with family. It had everything we needed in a beautiful location."
Country home-just steps from Coon Creek and a short drive to Mississippi River

Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

2.0 star property
10.0 out of 10, Exceptional, (2)
"We had a wonderful stay and our host was great! Wonderful property with everything we needed for a fun, stress-free stay. Three bedrooms, each with its own bath, was ideal! The great room was perfect for group, sit-down dinners and party games!"
Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

Nice Cape Cod home near the Mississippi River (Scenic River Inn)

9.8 out of 10, Exceptional, (126)
"Very clean charming property!"
Nice Cape Cod home near the Mississippi River (Scenic River Inn)

Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

10.0 out of 10, Exceptional, (150)
"Great views, very clean, fun activities"
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Blakley Hobbit Charming 2-bedroom country house with AC, WiFi in soothing Viola

8.8 out of 10, Excellent, (3)
"Nice place across from a campground. "
The price is AED 661
AED 1,151 total
includes taxes & fees
6 Jun - 7 Jun
Blakley Hobbit Charming 2-bedroom country house with AC, WiFi in soothing Viola

Secluded luxury House in the Hills w/king bed

10.0 out of 10, Exceptional, (26)
"Perfect for the friend group to relax and catch up with each other. Close to activities in Lacrosse. Quiet and peaceful location. "
Secluded luxury House in the Hills w/king bed

Queen Anne Stay

10.0 out of 10, Exceptional, (2)
"The house has lots of space and is just blocks from great dining and bars. Will absolutely book this again for future trips to Viroqua. "
Queen Anne Stay

River Valley Cabin

10.0 out of 10, Exceptional, (78)
"Amazing location. Gracious and helpful hosts."
River Valley Cabin

Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

9.0 out of 10, Wonderful, (26)
"This was a great location for our women's weekend away. Plenty of room for the 5 of us. Property tour, hike and living quarters were as advertised. Ed was an attentive manager and addressed our requests in a timely manner. Fire ban kept us from enjoying a campfire. If you're a light sleeper - consider earplugs if on the lower level (some noise/movement heard) overnight which is expected in a shared lodge. "
The price is AED 559
AED 1,116 total
includes taxes & fees
6 Jun - 7 Jun
Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

Luxurious home with hot tub, electric fireplace, and stunning views

2.0 star property
10.0 out of 10, Exceptional, (15)
"Did our souls good to stay here, just what the dr. ordered."
Luxurious home with hot tub, electric fireplace, and stunning views

Hygge Hideaway. Pet friendly, cozy retreat & 3 minute walk to the river!

10.0 out of 10, Exceptional, (46)
"Fantastic place to stay. Clean and many convenient items included. Would stay again."
Hygge Hideaway. Pet friendly, cozy retreat & 3 minute walk to the river!

Charming 3-bedroom house with WiFi and AC in beautiful La Crosse

9.8 out of 10, Exceptional, (7)
"Excellent communication from our host! He was very accommodating to my last minute requests (early arrival and ski team dinner). The entire house was immaculate. We loved the view, especially in the morning with coffee in the seating area off of the kitchen. I wish that we had more time to spend in the game room or relaxing in front of the fireplace. Thank you for a wonderful weekend!"
Charming 3-bedroom house with WiFi and AC in beautiful La Crosse

Unwind at the Lotus house Opal suite.

9.6 out of 10, Exceptional, (10)
"Very great location and owner is great"
Unwind at the Lotus house Opal suite.

Timber Coulee Creek in backyard, king size bed, grill on deck, large garage.

10.0 out of 10, Exceptional, (33)
"Would try to stay here on my next trip."
Timber Coulee Creek in backyard, king size bed, grill on deck, large garage.

Cozy and charming. Your home away from home in the heart of Viroqua.

10.0 out of 10, Exceptional, (12)
"It was really nice to stay at the little yellow house and relax after being out, hunting in the cold the entire day. The host is extremely responsive, friendly, and accommodating. We would love to stay again in the future if available."
Cozy and charming. Your home away from home in the heart of Viroqua.

Tiny House on Upper Iowa River w/ hot tub

8.8 out of 10, Excellent, (33)
"Cutest Tiny Home with some beautiful views! Gabby was easy to work with and we enjoyed our stay! "
The price is AED 679
AED 1,172 total
includes taxes & fees
6 Jul - 7 Jul
Tiny House on Upper Iowa River w/ hot tub

Wilson Schoolhouse Inn----- Ideal For Family Gatherings Or 2-3 Couples

10.0 out of 10, Exceptional, (103)
"Beautiful place full of history and nestled in the forest. Quiet place with awesome ambiance, open concept floor plan and close to town, the river, hiking trails and downhill skiing. Dick and Lisbeth were wonderful and very accommodating, will definitely stay with them again."
Wilson Schoolhouse Inn----- Ideal For Family Gatherings Or 2-3 Couples

Large property close to the Mississippi River. Sleeps up to 12. Pet Friendly.

9.8 out of 10, Exceptional, (20)
"Great location and spacious house. Really enjoyed our stay. Easy access in and out. Highly recommend! "
Large property close to the Mississippi River. Sleeps up to 12. Pet Friendly.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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