De Soto Vacation Rentals from AED 176: Search Short-Term Rentals

Q: What are some of the best vacation home rentals that De Soto has to offer?

Gated 35-Acre De Soto Estate: Pool, Lake & Patio! : Visitors like this De Soto vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

A rocky landscape with large boulders and a forested hill in the background.

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Our top choices for De Soto vacation rentals

A cozy living room with wooden walls, a large window, a television, and comfortable seating.

1. 82 Acre Hobby Farm with Lincoln Log Cabin

De Soto

DeAnn H.

AED 959 total

includes taxes & fees

15 Nov - 16 Nov

A deck with outdoor furniture, a table, and a green umbrella.

2. 2BR/1BA Pet-Friendly Escape Near Wineries & Hiking Trails

De Soto

Stephen L.

AED 887 total

includes taxes & fees

30 Nov - 1 Dec

A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.

3. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

Jose

AED 534 total

includes taxes & fees

14 Dec - 15 Dec

A covered outdoor seating area with a table and chairs, string lights, and a gravel ground.

4. Clifford's Country Cottage

Bonne Terre

Philip

AED 535 total

includes taxes & fees

15 Nov - 16 Nov

A modern two-story house with a stone exterior, large windows, and a deck with outdoor seating.

5. Vallee Suite at Baetje Farms

Bloomsdale

Heather

AED 485 total

includes taxes & fees

15 Nov - 16 Nov

6. Amoureux Suite at Baetje Farms

Bloomsdale

AED 485 total

includes taxes & fees

15 Nov - 16 Nov

A wooden deck with two Adirondack chairs and a hammock.

7. Tiny Houses of French Village

French Village

Chris

AED 1,250 total

includes taxes & fees

16 Nov - 17 Nov

A red door with a white-framed window and a small outdoor area with a metal chair and a table.

8. Upstairs 2 bedroom Private Apt Off I- 55 in Pevely

Pevely

Caren L.

AED 826 total

includes taxes & fees

15 Nov - 16 Nov

9. Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Imperial

Tommy H.

AED 355 total

includes taxes & fees

18 Nov - 19 Nov

An outdoor patio area with a seating arrangement and a fire pit.

10. Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.

Bloomsdale

Blake H.

AED 1,006 total

includes taxes & fees

15 Nov - 16 Nov

A tree with a stone ring around its base, a stream flowing through a grassy area, and a forest in the background.

11. Peter Ray House

Maeystown

Eric

AED 782 total

includes taxes & fees

15 Nov - 16 Nov

A cabin with a wooden staircase leading to a deck, surrounded by trees with autumn foliage.

12. Shady Pine Primitive Cabin 2 @Spring Lake Ranch

Potosi

Stephan

AED 273 total

includes taxes & fees

15 Nov - 16 Nov

A residential backyard with a lawn, a trash bin, and a house in the background.

13. Cozy Serene home off 55 Queen Bed Smart TVs Wi-Fi

Pevely

James S.

AED 867 total

includes taxes & fees

15 Nov - 16 Nov

A living room with a fireplace, a sofa, a dining table with chairs, and a lamp.

14. Stay On Festus Main 2 bedroom 1.5 bath Near Mercy

Festus

Jennifer B.

AED 911 total

includes taxes & fees

16 Nov - 17 Nov

A poolside area with two wooden lounge chairs and a table, surrounded by greenery and a clear sky.

15. Tiny Houses of French Village Tranquil & Relaxing

French Village

Shannon S.

AED 1,208 total

includes taxes & fees

16 Nov - 17 Nov

A pool with two lounge chairs facing the water, surrounded by trees and a clear sky.

16. Tiny Houses of French Village Tranquil & Relaxing

French Village

James F.

AED 1,208 total

includes taxes & fees

16 Nov - 17 Nov

A fire pit surrounded by wooden chairs in an outdoor setting with string lights.

17. Beautiful historical two story stone farmhouse

Bonne Terre

Jeannine

AED 1,455 total

includes taxes & fees

16 Nov - 17 Nov

A modern kitchen with grey cabinets, a black refrigerator, and a microwave.

18. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Farmington

Ben C.

AED 922 total

includes taxes & fees

15 Nov - 16 Nov

A stone fire pit surrounded by four wooden Adirondack chairs in a grassy yard.

19. Cozy Three bedroom home in Central Farmington

Farmington

Theresa

AED 894 total

includes taxes & fees

15 Nov - 16 Nov

A hot tub with a view of a park and trees in the background.

20. Homestead Hideaway + Hot Tub

Fults

Janice G.

AED 985 total

includes taxes & fees

17 Nov - 18 Nov

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Find vacation rentals that suit your style

Top De Soto Hotel Reviews

A Holiday Inn Express & Suites building with a gas station in front.

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

10/10 Excellent

Anonymous traveler

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

Pear Tree Inn St. Louis Arnold

Arnold

10/10 Excellent

Blaine

A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

Drury Inn & Suites St. Louis Arnold

Arnold

10/10 Excellent

Rachel

A hotel room with a bathroom, a bed, a sofa, a coffee table, a TV, and a microwave.

Comfort Inn Festus - St Louis South

Festus

10/10 Excellent

CindyLucy

A spacious lobby with a modern design, featuring a large seating area with purple and gray chairs, a patterned carpet, and a cityscape mural on the wall.

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

10/10 Excellent

Adrian

A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.

Crown Pointe Lodge, BW Signature Collection

Farmington

10/10 Excellent

Scott

A narrow stone pathway leading to a brick house with a dark wooden door and a window with a white frame.

Corner George Inn Bed & Breakfast

Maeystown

10/10 Excellent

We stayed from 3/29 through 4/1. Unique place sitting directly next to a clear babbling brook. We stayed in The Loft room and it is very big, with a claw-foot tub and full kitchen that was stocked with dishes. The pillows and bed were devine. We slept completely through the night and woke feeling so refreshed. It was so quiet in the evenings that it was easy to picture yourself there in the 1890's with the world turning much slower around you. Many places were not open though since it was still...

Richard

A large, two-story house with a wrap-around porch and a central tower.

The Conner House B&B

Prairie du Rocher

10/10 Excellent

Waited until the last minute to book a place to stay for an event in Redbud. Everything there was booked so had to expand our search and boy was that a blessing. Ended up at the Conner House and found a beautifully restored 1906 bed and breakfast. Very charming and inviting and took us back in time. Had a wonderful stay, learned a little history and had a great breakfast all thanks to our hostesses Pat & Connie. Forget the national chain - this is a must see house and getting to spend the...

Anonymous traveler

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

10/10 Excellent

Rebecca

A hotel room with two beds, a large wall-mounted picture of a waterfall, a bedside table with a lamp, and a door.

Super 8 by Wyndham Farmington

Farmington

10/10 Excellent

MarBella

A motel with a covered parking area, a brick facade, and a sign indicating it is number 8.

Super 8 by Wyndham Potosi

Potosi

10/10 Excellent

Anonymous traveler

Frequently Asked Questions

Can I find a vacation rental in De Soto?

Yes, there are vacation rentals close to the most popular attractions in De Soto, or you can choose a secluded option if you're looking for a relaxing stay. De Soto is known for its restaurants.

What are some of the best vacation home rentals that De Soto has to offer?

Gated 35-Acre De Soto Estate: Pool, Lake & Patio!: Visitors like this De Soto vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in De Soto?

Sunrise Lake Beach and Big River are a couple of lovely local spots to get outside and enjoy nature. While here, Washington State Park and Big Lake are other places worth a visit.

What’s a vacation rental in De Soto like?

Vacation rentals are private properties you can stay in for several days or longer in De Soto. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you want. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family getaway.

De Soto Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for De Soto vacation rentals

1. 82 Acre Hobby Farm with Lincoln Log Cabin

2. 2BR/1BA Pet-Friendly Escape Near Wineries & Hiking Trails

3. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

4. Clifford's Country Cottage

5. Vallee Suite at Baetje Farms

6. Amoureux Suite at Baetje Farms

7. Tiny Houses of French Village

8. Upstairs 2 bedroom Private Apt Off I- 55 in Pevely

9. Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

10. Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.

11. Peter Ray House

12. Shady Pine Primitive Cabin 2 @Spring Lake Ranch

13. Cozy Serene home off 55 Queen Bed Smart TVs Wi-Fi

14. Stay On Festus Main 2 bedroom 1.5 bath Near Mercy

15. Tiny Houses of French Village Tranquil & Relaxing

16. Tiny Houses of French Village Tranquil & Relaxing

17. Beautiful historical two story stone farmhouse

18. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

19. Cozy Three bedroom home in Central Farmington

20. Homestead Hideaway + Hot Tub

Find vacation rentals that suit your style

Top De Soto Hotel Reviews

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

10/10 Excellent

Frequently Asked Questions

Can I find a vacation rental in De Soto?

What are some of the best vacation home rentals that De Soto has to offer?

What’s there to see and do in De Soto?

What’s a vacation rental in De Soto like?