Find hotels in Depew, NY from AED 250

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Our top choices for Depew hotels

Comfort Inn & Suites Niagara Falls Blvd USA

Comfort Inn & Suites Niagara Falls Blvd USA
2.5 star property
La Salle
8.8 out of 10, Excellent, (1397)
"Had a very nice stay! Would stay again!"
United States
Matt
The price is AED 276
AED 314 total
includes taxes & fees
9 Jan - 10 January 2026
Comfort Inn & Suites Niagara Falls Blvd USA

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
2.5 star property
Buffalo
8.2 out of 10, Very Good, (1005)
Located just minutes from Buffalo Niagara International Airport, this hotel offers a refreshing indoor pool and fitness center. Enjoy free breakfast and WiFi before exploring nearby Walden Galleria Mall or catching the free airport shuttle.

"The staff were exceptional, the room was beautiful and clean, the location couldn’t be beat and it was in our price range!!"
United States
Jen
The price is AED 364
AED 414 total
includes taxes & fees
6 Jan - 7 January 2026
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1908)
Just 1.1 mi from Buffalo Airport with free 24-hour shuttle, this hotel offers hiking trails and kayaking options nearby. Enjoy free breakfast, WiFi, parking, and easy access to Walden Galleria Mall and University At Buffalo.

"Clean rooms, good and fresh breakfast, location."
Canada
Felipe
The price is AED 263
AED 299 total
includes taxes & fees
13 Jan - 14 January 2026
Sleep Inn & Suites Buffalo Airport

Buffalo Airport Hotel

Buffalo Airport Hotel
3.0 star property
Buffalo
8.0 out of 10, Very Good, (2801)
Just 1 mile from the airport with 24-hour free shuttle, this quiet retreat features Sports 365 Bar & Grill serving American cuisine. Travelers love the helpful staff, free WiFi, parking, and proximity to dining options and Walden Galleria Mall.

"Perfect for staying overnight !! "
United States
Lorena
The price is AED 242
AED 275 total
includes taxes & fees
25 Dec - 26 Dec
Buffalo Airport Hotel

Hampton Inn Buffalo-Airport / Galleria Mall

Hampton Inn Buffalo-Airport / Galleria Mall
2.5 star property
Buffalo
8.6 out of 10, Excellent, (1000)
Enjoy seamless travel with the complimentary airport shuttle at this Buffalo hotel. Just minutes from Walden Galleria Mall and offering an indoor pool, 24-hour fitness center, and free breakfast. Guests consistently praise the helpful staff and convenient shopping access.

"Clean room, friendly staff and great location. "
Canada
Lisa
The price is AED 393
AED 447 total
includes taxes & fees
23 Jan - 24 January 2026
Hampton Inn Buffalo-Airport / Galleria Mall

La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst
3.0 star property
Buffalo
8.4 out of 10, Very Good, (1969)
Experience relaxing accommodations just minutes from University at Buffalo and Boulevard Place. This hotel offers an indoor pool, fitness center, and complimentary breakfast, WiFi, and parking. Guests consistently praise the comfortable beds and attentive staff.

"The hotel was great clean, accesable. quiet, close to UB"
United States
Bruce
The price is AED 309
AED 352 total
includes taxes & fees
30 Dec - 31 Dec
La Quinta Inn & Suites by Wyndham Buffalo Amherst

Hampton Inn Buffalo-Hamburg

Hampton Inn Buffalo-Hamburg
2.5 star property
Hamburg
9.0 out of 10, Wonderful, (1002)
Just 10 minutes from Lake Erie and Highmark Stadium, this Hamburg hotel offers a refreshing indoor pool and 24-hour fitness center. Guests rave about the helpful staff and spotless rooms. Enjoy free breakfast, WiFi, and parking during your stay.

"Room was very clean and staff friendly"
United States
Peter
The price is AED 361
AED 411 total
includes taxes & fees
20 Jan - 21 January 2026
Hampton Inn Buffalo-Hamburg

Microtel Inn & Suites by Wyndham Niagara Falls

Microtel Inn & Suites by Wyndham Niagara Falls
2.5 star property
Niagara Falls
8.2 out of 10, Very Good, (1000)
This hotel offers free breakfast, WiFi, and parking, with a 24-hour fitness center for active travelers. Just a short drive from Niagara Falls State Park and Fashion Outlets, it's also near Clifton Hill and the casino.

"The staff friendly and the room was very clean and comfortable."
United States
Lin
The price is AED 264
AED 301 total
includes taxes & fees
25 Dec - 26 Dec
Microtel Inn & Suites by Wyndham Niagara Falls

Red Roof Inn Buffalo - Niagara Airport

Red Roof Inn Buffalo - Niagara Airport
2.0 star property
Bowmansville
7.2 out of 10, Good, (1003)
Discover a peaceful haven with free WiFi and parking just 15 minutes from University At Buffalo. Located close to restaurants and shopping, this hotel offers clean rooms and attentive 24-hour service near Buffalo Niagara International Airport.

"Loved every moment, clean, well affordable and the staff were amazing "
United States
Joselyin
The price is AED 202
AED 230 total
includes taxes & fees
25 Dec - 26 Dec
Red Roof Inn Buffalo - Niagara Airport

DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst
4.0 star property
Buffalo
7.8 out of 10, Good, (1000)
"Everything look great we will come back again😀"
United States
Cheekeong
The price is AED 314
AED 357 total
includes taxes & fees
6 Jan - 7 January 2026
DoubleTree by Hilton Hotel Buffalo - Amherst

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport
3.0 star property
Buffalo
8.2 out of 10, Very Good, (1271)
Experience quiet comfort steps away from Buffalo Niagara Airport with 24-hour shuttle service. The indoor pool offers relaxation after exploring nearby Walden Galleria Mall. Free breakfast, WiFi, and parking add value to this ideally situated hotel.

"Very nice stay"
United States
James
The price is AED 362
AED 412 total
includes taxes & fees
19 Jan - 20 January 2026
Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Hamburg - Buffalo South

Comfort Inn & Suites Hamburg - Buffalo South
2.5 star property
Hamburg
7.4 out of 10, Good, (1002)
Near Lake Erie and Highmark Stadium, this Hamburg hotel offers an indoor pool for morning swims and a fitness center. Guests praise the helpful staff and clean rooms, with free breakfast, WiFi, and parking enhancing your stay.

"I was pleasantly surprised by this hotel. It was clean, quiet, and breakfast was good."
United States
Cindy
The price is AED 262
AED 298 total
includes taxes & fees
23 Jan - 24 January 2026
Comfort Inn & Suites Hamburg - Buffalo South

Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG
2.5 star property
Grand Island
8.8 out of 10, Excellent, (1622)
"Clean room, amazing staff, good amenities.. Really enjoyed our family stay there..!"
Canada
Sriprakash
The price is AED 272
AED 309 total
includes taxes & fees
4 Jan - 5 January 2026
Holiday Inn Express Grand Island - Niagara Falls by IHG

Spark by Hilton Lockport

Spark by Hilton Lockport
3.0 star property
Lockport
7.4 out of 10, Good, (74)
Discover tranquility at this quiet Lockport hotel offering free continental breakfast, WiFi, and parking. Work out in the fitness center before exploring nearby attractions like Four Seasons Players and Big Bridge. Guests consistently praise the helpful staff and clean rooms.

"Great stay, thanks!"
Canada
Shirmilla
The price is AED 238
AED 269 total
includes taxes & fees
30 Dec - 31 Dec
Spark by Hilton Lockport

Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Downtown Buffalo
8.8 out of 10, Excellent, (1006)
"Hotel was very clean and the staff was friendly. My room was larger than expected. Breakfast was well stocked and had good variety. Great location also!"
United States
Holly
The price is AED 479
AED 559 total
includes taxes & fees
20 Jan - 21 January 2026
Hampton Inn & Suites Buffalo Downtown

La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport
3.0 star property
Buffalo
8.0 out of 10, Very Good, (1363)
Just 2.6 mi from Buffalo Airport with 24-hour free shuttle service. This hotel offers convenient access to Walden Galleria Mall and University At Buffalo - North Campus. Guests love the quiet atmosphere, helpful staff, free breakfast, WiFi and parking.

"Always clean and friendly!"
Canada
Stacy
The price is AED 278
AED 316 total
includes taxes & fees
18 Jan - 19 January 2026
La Quinta Inn by Wyndham Buffalo Airport

Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY
2.5 star property
Buffalo
9.4 out of 10, Exceptional, (1994)
Comfortable beds await at this friendly Buffalo hotel with indoor pool and 24-hour fitness center. Located near Walden Galleria Mall and Northtown Center, guests love the complimentary breakfast. Buffalo Niagara International Airport is just 20 minutes away.

"Great room, staff, breakfast, and pool- would definitely stay here again!"
United States
Madison
The price is AED 389
AED 442 total
includes taxes & fees
5 Jan - 6 January 2026
Hampton Inn Buffalo - Amherst, NY

Econo Lodge Darien Lakes

Econo Lodge Darien Lakes
2.0 star property
Corfu
7.8 out of 10, Good, (804)
This business-friendly hotel offers free WiFi and parking, plus a fitness center for active travelers. Enjoy nearby hiking trails and snowmobiling adventures, with Akron Falls Park in the vicinity. Clean rooms and helpful staff ensure a comfortable stay.

"Staff was really friendly!"
United States
Stephen
The price is AED 248
AED 276 total
includes taxes & fees
6 Jan - 7 January 2026
Econo Lodge Darien Lakes

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY
2.5 star property
Buffalo
8.2 out of 10, Very Good, (1292)
Situated near Lake Erie, this hotel offers a convenient location with free breakfast, WiFi, and parking. After morning laps in the indoor pool, explore nearby KeyBank Center or unwind on the terrace. Rooms include refrigerators and microwaves for added comfort.

"The breakfast was very good for a free hotel breakfast. And the staff was very pleasant. "
United States
Rhonda
The price is AED 450
AED 511 total
includes taxes & fees
13 Jan - 14 January 2026
Country Inn & Suites by Radisson, Buffalo South I-90, NY

Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1001)
"Friendly staff, easy parking"
United States
Brittany
The price is AED 309
AED 352 total
includes taxes & fees
29 Dec - 30 Dec
Quality Inn Near Walden Galleria Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

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Hotels in Depew with star-rating

Find out more about Depew

Top reasons to visit Depew

  • Family-Friendly Activities: Depew is perfect for families, featuring amusement parks and engaging recreational options for all ages.
  • Charming Neighborhoods: Explore the rich history of old mansions and enjoy the local atmosphere in Depew's inviting neighborhoods.
  • Diverse Shopping: Experience a variety of shopping centers and malls, offering something for every shopper.
  • Cultural Attractions: Visit modern colleges, urban parks, and arts centers that highlight the town's vibrant culture.
  • Convenient Accommodations: Choose from a range of hotels and motels that cater to all types of travelers.

Find great hotels near Depew

Discover a range of hotel accommodations in Depew, New York, designed to meet the needs of every traveler. From cozy motels to full-service hotels, you'll find options that cater to business travelers, pet owners, and those seeking an LGBTQIA-friendly environment. Whether you’re looking for the best hotels or simply searching for available options, Depew offers welcoming stays that ensure a comfortable and enjoyable vacation experience.

  • M Hotel Buffalo: M Hotel Buffalo offers a unique blend of modern comfort and inclusivity, catering especially to the LGBTQIA community. Located a mere 4.8km from Depew, this 3.5-star hotel is ideal for business travelers seeking a welcoming atmosphere. Guests can enjoy stylishly designed rooms equipped with essential amenities, along with access to a fitness center and a business center for their convenience. The hotel's commitment to inclusivity is evident through its affiliation with LGBTQI travel guides, making it a preferred choice for those looking for a vacation experience that embraces diversity.
  • Country Inn & Suites by Radisson, Buffalo South I-90, NY: Just 9.7km from Depew, the Country Inn & Suites by Radisson is perfect for travelers who want to bring their furry friends along. This hotel provides a cozy, pet-friendly environment, allowing dogs and cats with certain restrictions. Guests can enjoy a complimentary breakfast, an indoor pool, and a fitness center, making it suitable for both business and leisure stays. With its welcoming atmosphere and convenient amenities, this hotel ensures a comfortable stay for families and pet owners alike.
  • Motel 6 Buffalo, NY - Airport - Williamsville: Located only 4.8km from Depew, Motel 6 Buffalo is an excellent choice for budget-conscious travelers seeking a pet-friendly lodging option. This motel allows pets at no additional charge, making it convenient for those traveling with their furry companions. The property features comfortable rooms, free Wi-Fi, and a 24-hour front desk for added convenience. With its no-frills approach and welcoming policies for pets, Motel 6 provides a straightforward yet comfortable stay for all guests.

Where to stay in Depew

Depew, New York, offers a delightful mix of family-friendly activities and charming neighborhoods perfect for your vacation. Explore the rich history of old mansions, enjoy outdoor adventures, and take in the vibrant local atmosphere. With its convenient location, Depew serves as a great base to venture into nearby cities, where you can experience a blend of business, romance, and friendly vibes. This area is ideal for both family getaways and city-themed explorations.

  • Buffalo: As a vibrant metropolis, Buffalo is the largest city in the region and serves as a cultural hub. Located in close proximity to Depew, it offers a variety of experiences for travelers seeking outdoor activities, family fun, and city-themed adventures. Visitors flock to Buffalo primarily from June to August, when the weather is warm and the city hosts numerous events. Highlights include expansive recreational areas, bustling shopping centers, and iconic local landmarks such as sports stadiums and the breathtaking Niagara Falls. Don’t miss out on exploring Buffalo’s rich history and diverse culinary scene.
  • Cheektowaga: This charming village, positioned just 4.8km from Depew, provides a delightful mix of family-friendly and business-themed experiences. Cheektowaga sees a steady stream of visitors, particularly from March to April and during the summer months. Travelers enjoy the convenience of nearby shopping centers and educational institutions. The village is also home to several notable landmarks, including modern colleges and national parks, making it a great spot for both leisure and learning. Enjoy the local parks and community events that bring Cheektowaga to life.
  • Bowmansville: Another quaint city located 4.8km away from Depew, Bowmansville is known for its family-oriented atmosphere and business-friendly environment. Peak travel times occur from June to August, when visitors can enjoy the warm weather and local attractions. This city offers a variety of shopping options and educational facilities, along with nearby attractions such as theme parks and sports stadiums. Bowmansville is the perfect destination for families looking to blend fun with a bit of adventure, all while enjoying the charm of a small city.

Things to do near Depew

Depew offers a delightful blend of family-friendly activities and urban charm, making it perfect for a vacation. Visitors can explore shopping centers and malls, enjoy the excitement of an amusement park, and indulge in a captivating theater experience. With a variety of shopping options and major attractions, there's something for everyone to enjoy in this vibrant town.

Shopping

In Depew, you can shop at Walden Galleria Mall, just 4.8km away, offering a vibrant atmosphere with entertainment options. Eastern Hills Mall, located 8.0km away, also provides a family-friendly shopping experience. Additionally, visit Broadway Market, 11.3km away, for local goods and a unique city vibe.

Recreation

Holiday Twin Rinks offers a lively ice skating experience just 3.2km from Depew, perfect for adventure and entertainment. Diamond Hawk Golf Course, also 3.2km away, provides a scenic outdoor setting for golf enthusiasts. For a broader sports experience, visit the Northtown Center at Amherst, located 12.9km from Depew.

Adventure

Experience the thrill of racing at Pole Position Raceway, where you can enjoy high-speed karting just 4.8km from Depew. For a scenic outdoor adventure, explore the Amherst Canalway Trail, located 19.3km away, perfect for biking and hiking. Don’t miss the Buffalo Ski Club, a ski field 24.1km away, ideal for winter sports enthusiasts.

Nightlife

Catch a captivating performance at the Lancaster Opera House, just 3.2km away, for a romantic cultural experience. For family fun, head to Lasertron, 12.9km away, where adventure awaits. Also, don’t miss the University At Buffalo Center for the Arts, offering entertainment and culture vibes, also 12.9km from Depew.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Depew

To save money on your trip to Depew, consider visiting between January and March for lower accommodation rates, avoiding the more expensive summer months. Booking your stay on a Tuesday can also help you find cheaper options. Use Expedia to compare hotel prices and sort by the lowest rates, and consider package deals that combine flights, hotels, and activities for additional savings. Take advantage of free local attractions and use public transport for affordable travel around the area. Being savvy with your bookings can lead to significant savings during your visit.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Depew are January to March, where the prices are slightly lower. This is in comparison to July to September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Depew is Tuesday. The most expensive day to stay in Depew is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred hotel type. For the best prices and deals, be sure to sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Depew with your flights and activities through an Expedia package deal.

Find the best attractions near Depew

Depew, New York, offers a blend of family-friendly activities and urban culture, making it ideal for outdoor and city-themed vacations. Visitors can explore local attractions such as modern colleges and universities, urban parks, and arts centers. Nearby, you'll find additional points of interest that enhance your experience, ensuring a fulfilling getaway filled with cultural and recreational opportunities suitable for everyone.

  • University At Buffalo - North Campus: Experience the vibrant atmosphere of this modern university, just 12.9km from Depew. The campus is known for its impressive architecture and lush green spaces, making it a perfect spot for a leisurely stroll while soaking in the academic ambiance.
  • Shea's Performing Arts Center: Located 14.5km away, this historic venue offers a rich cultural experience. Attend a show or simply admire the stunning architecture, which reflects the grandeur of the performing arts in Buffalo.
  • Roswell Park Cancer Institute: Just 12.9km from Depew, this institute combines recreation and historical significance. Explore its beautiful grounds while learning about its pioneering contributions to cancer research and patient care.

Best time to go to Depew

The best time to visit Depew can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Depew falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Depew falls in January, visitor numbers are average and weather is very cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January25.0°F (-3.9°C)Light RainVery CloudyAverageSlightly Low
February25.9°F (-3.4°C)Light RainMostly CloudyAverageSlightly Low
March34.2°F (1.2°C)Light RainMostly CloudyAverageSlightly Low
April45.0°F (7.2°C)Light RainMostly CloudySlightly HighAverage
May57.6°F (14.2°C)Light RainMostly SunnyAverageAverage
June65.5°F (18.6°C)Light RainMostly SunnyAverageAverage
July71.1°F (21.7°C)Light RainMostly SunnySlightly HighSlightly High
August69.8°F (21.0°C)Light RainMostly SunnyAverageSlightly High
September63.5°F (17.5°C)Light RainMostly SunnySlightly HighSlightly High
October52.3°F (11.3°C)Light RainMostly CloudySlightly LowAverage
November40.5°F (4.7°C)Light RainMostly CloudySlightly LowAverage
December32.4°F (0.2°C)Light RainMostly CloudySlightly LowAverage

The nearest major airports for your trip to Depew

When planning your visit to Depew, New York, you have several airport options. Buffalo Niagara International Airport (BUF) is the closest, located 4.8km away, with nearby hotels such as the 5-star Curtiss Hotel and the 4-star DoubleTree by Hilton Hotel Buffalo - Amherst. Transportation services to BUF include transfers and shuttles. Greater Rochester International Airport (ROC) is 88.5km from Depew, featuring hotels like the DoubleTree by Hilton Rochester. Niagara Falls International Airport (IAG) is 29.0km away, with accommodations such as the Seneca Niagara Resort & Casino. Each airport provides convenient access to the surrounding hotel options.

Frequently asked questions

What's the best place for a stay in Depew?
Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Hyatt Regency Buffalo / Hotel and Conference Center and Garden Place Hotel. See all available top hotels, or vacation rentals in Depew.
What's the top vacation rental in Depew?
Cozy Buffalo Getaway – Minutes to Downtown & Bills Stadium: This vacation home rental outside of Depew has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Depew.
If I need to cancel my hotel reservation in Depew, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.
Where can I learn more about changing or cancelling my trip to Depew?
For more information about picking new dates or cancelling your trip to Depew, click here.
What are some accommodations with pools in Depew?
M Hotel Buffalo: Hotel, 6-minute walk from Walden Galleria Mall. Features buffet, an indoor pool, and free self parking. Hyatt Regency Buffalo / Hotel and Conference Center and Holiday Inn Express Grand Island - Niagara Falls by IHG are a couple of other choices that feature an onsite pool. View all hotels with pools in Depew.
What's the best place to stay near Buffalo Niagara International Airport (BUF)?
Days Hotel by Wyndham Buffalo Airport is a popular 3-star hotel featuring free breakfast and a restaurant. It's located a short 0.3 mi (0.5 km) from Buffalo Niagara Intl. Airport. Other places to stay within close proximity to the airport include Hilton Garden Inn Buffalo Airport and Courtyard Buffalo Airport.
What is staying in Depew like?
Visitors can enjoy all that Depew has to offer including the shopping, restaurants, and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodations to choose from. Find out more about Depew.
What are the top places to visit in Depew?
Places to visit in the wider area include Holiday Twin Rinks, Walden Galleria Mall, and Samuel's Grande Manor. You'll also find Glen Falls and Buffalo Central Terminal in the area. Check out what more to see and do in Expedia's Depew guide.
How should I get around Depew?
To see more of the larger area, ride aboard one of the trains from Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.
What's the weather like in Depew?
The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Depew are January, March, February, and December, with each month seeing an average of 17 inches of snowfall.

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