Search Vacation Homes in Des Moines

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Des Moines vacation homes

2-bedroom vacation home just 3 minutes drive to Drake University

2-bedroom vacation home just 3 minutes drive to Drake University
Waveland Park
10.0 out of 10, Exceptional, (62 reviews)
"Great place to stay"
United States
Ben C.
2-bedroom vacation home just 3 minutes drive to Drake University

Beautiful home minutes from downtown!

Beautiful home minutes from downtown!
Des Moines
9.2 out of 10, Wonderful, (32 reviews)
"The location was close to downtown which was helpful as we drove to the Caseys Center three days in a row. It was in a quiet neighborhood where we felt safe. The house was spacious and had everything we needed for our four night stay. "
United States
Carla S.
The price is AED 430
AED 1,008 total
includes taxes & fees
1 Jun - 2 Jun
Beautiful home minutes from downtown!

1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU
West Des Moines
8.8 out of 10, Excellent, (8 reviews)
"The location was absolutely perfect being on the very edge of Des Moines. It was quiet, no city distractions and very private. The space was very clean and Clayton was very friendly and personable. We definitely would stay again!"
United States
Melissa C.
The price is AED 380
AED 652 total
includes taxes & fees
31 May - 1 Jun
1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

Roomy 4BR by Drake Sleeps 13 HUGE yard

Roomy 4BR by Drake Sleeps 13 HUGE yard
Drake
7.0 out of 10, Good, (9 reviews)
"Good"
United States
Laurie P.
The price is AED 368
AED 1,174 total
includes taxes & fees
25 May - 26 May
Roomy 4BR by Drake Sleeps 13 HUGE yard

Fun, group friendly house close to fair! Sleeps 8

Fun, group friendly house close to fair! Sleeps 8
Fairground
9.0 out of 10, Wonderful, (26 reviews)
"Perfect for what we needed. "
United States
Brian I.
The price is AED 514
AED 856 total
includes taxes & fees
31 May - 1 Jun
Fun, group friendly house close to fair! Sleeps 8

Cozy Bungalow Retreat

Cozy Bungalow Retreat
Greater South Side
The price is AED 347
AED 697 total
includes taxes & fees
8 Jun - 9 Jun
Cozy Bungalow Retreat

The Iowa Fair House - Games + Walk to Main Gate

The Iowa Fair House - Games + Walk to Main Gate
Fairground
10.0 out of 10, Exceptional, (3 reviews)
"Rooms clean. Location great! Host was easy to communicate with and very friendly!"
United States
Lily T.
The price is AED 463
AED 827 total
includes taxes & fees
1 Jun - 2 Jun
The Iowa Fair House - Games + Walk to Main Gate

NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!

NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!
Urbandale
9.4 out of 10, Exceptional, (82 reviews)
"Nice place to stay"
United States
kevin s.
The price is AED 493
AED 1,687 total
includes taxes & fees
1 Jun - 2 Jun
NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!

New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location
Ankeny
10.0 out of 10, Exceptional, (25 reviews)
"We had a great stay! "
United States
Katie V.
The price is AED 512
AED 1,220 total
includes taxes & fees
25 May - 26 May
New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

5 Min to Adventureland and Casino - Fenced in yard

5 Min to Adventureland and Casino - Fenced in yard
Altoona
9.8 out of 10, Exceptional, (7 reviews)
"We enjoyed this place and its location. The beds were awesome and felt safe in the neighborhood. "
United States
Danielle L.
The price is AED 327
AED 1,057 total
includes taxes & fees
1 Jun - 2 Jun
5 Min to Adventureland and Casino - Fenced in yard

Beautiful 3-bedroom house with AC in adorable Des Moines

Beautiful 3-bedroom house with AC in adorable Des Moines
Beaverdale
9.4 out of 10, Exceptional, (9 reviews)
"Great location close to friends. Hosts were great with awesome communication. "
United States
Karen G.
The price is AED 443
AED 1,014 total
includes taxes & fees
26 May - 27 May
Beautiful 3-bedroom house with AC in adorable Des Moines

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines
Des Moines
10.0 out of 10, Exceptional, (20 reviews)
"Place was awesome!"
United States
jeff w.
The price is AED 387
AED 577 total
includes taxes & fees
26 May - 27 May
Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10

The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10
Woodland Heights
10.0 out of 10, Exceptional, (73 reviews)
"Clean, comfortable, responsive host! Will stay again."
United States
Paul R.
The price is AED 488
AED 1,308 total
includes taxes & fees
25 May - 26 May
The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10

Modern Boho Townhome w/Hidden Reading Nook Near Downtown Des Moines!

Modern Boho Townhome w/Hidden Reading Nook Near Downtown Des Moines!
Des Moines
10.0 out of 10, Exceptional, (3 reviews)
"Such a cute townhouse and was perfect for our weekend away! The reading nook was so cozy. "
United States
Kylie F.
Modern Boho Townhome w/Hidden Reading Nook Near Downtown Des Moines!

A Charming Home Minutes to Downtown, Zoo, & Airport with Hidden Reading Nook!

A Charming Home Minutes to Downtown, Zoo, & Airport with Hidden Reading Nook!
Indianola Hills
10.0 out of 10, Exceptional, (24 reviews)
"Great place!"
United States
Kenneth M.
The price is AED 375
AED 790 total
includes taxes & fees
22 Jun - 23 Jun
A Charming Home Minutes to Downtown, Zoo, & Airport with Hidden Reading Nook!

A Private Boho-Modern Stay Minutes to Downtown w/ KING Bed and Hidden Nook!

A Private Boho-Modern Stay Minutes to Downtown w/ KING Bed and Hidden Nook!
Indianola Hills
10.0 out of 10, Exceptional, (16 reviews)
"Convenient location. Responsive owners"
United States
Juli G.
The price is AED 349
AED 773 total
includes taxes & fees
21 Jun - 22 Jun
A Private Boho-Modern Stay Minutes to Downtown w/ KING Bed and Hidden Nook!

2BR Family Charmer Duplex near Drake

2BR Family Charmer Duplex near Drake
Des Moines
8.6 out of 10, Excellent, (4 reviews)
"Was in town for work and was the perfect cozy and private place to be in."
United States
Genaro M.
The price is AED 339
AED 1,048 total
includes taxes & fees
15 Jun - 16 Jun
2BR Family Charmer Duplex near Drake

The Love Shack | Spacious Family Getaway • 5BR/3BA • 10 Mins to Downtown

The Love Shack | Spacious Family Getaway • 5BR/3BA • 10 Mins to Downtown
Windsor Heights
10.0 out of 10, Exceptional, (23 reviews)
"Perfect space for families, soft beds and very cozy! Can’t wait to come back in the summer and enjoy the back yard."
United States
Molly M.
The Love Shack | Spacious Family Getaway • 5BR/3BA • 10 Mins to Downtown

Urban Farmer House

Urban Farmer House
Greater South Side
8.6 out of 10, Excellent, (41 reviews)
"Nice place for the family! "
United States
Brandon G.
The price is AED 507
AED 1,345 total
includes taxes & fees
1 Jun - 2 Jun
Urban Farmer House

The Cactus House: A Boho Western Single Family Home Just South of Downtown DSM

The Cactus House: A Boho Western Single Family Home Just South of Downtown DSM
Des Moines
The Cactus House: A Boho Western Single Family Home Just South of Downtown DSM
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Des Moines Hotel Reviews