A serene lake with trees reflecting in the water, surrounded by a forest of tall, slender trees with autumn foliage.

Search Hotels in Orangeburg County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Orangeburg County hotels

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

1. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,482 reviews)
"A perfect place to stop on our way to Florida"
United States
Kate
The price is AED 294
AED 326 total
includes taxes & fees
9 Aug - 10 Aug
Baymont by Wyndham Santee
Property amenity

2. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,010 reviews)
"Property was clean and the breakfast was delicious would stay there again."
United States
Melissa
The price is AED 493
AED 547 total
includes taxes & fees
13 Aug - 14 Aug
Fairfield Inn & Suites by Marriott Santee
Free daily buffet breakfast

3. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (898 reviews)
"The room was very clean and the staff were extremely friendly"
United States
Jeffrey
The price is AED 358
AED 398 total
includes taxes & fees
16 Aug - 17 Aug
Tru By Hilton Santee
Seasonal outdoor pool

4. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,012 reviews)
"My stay was comfortable and awesome I will be visiting again"
United States
TaNikka
The price is AED 358
AED 398 total
includes taxes & fees
9 Aug - 10 Aug
Spark by Hilton Orangeburg
Snack bar

5. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,007 reviews)
"Great stay experience"
United States
Loshica
The price is AED 419
AED 465 total
includes taxes & fees
20 Aug - 21 Aug
Tru by Hilton Orangeburg
Exterior

6. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,013 reviews)
"Breakfast was the best , room was clean, will stay there again."
United States
edward
The price is AED 437
AED 485 total
includes taxes & fees
13 Aug - 14 Aug
Best Western Plus Santee Inn
Children's activities

7. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,001 reviews)
"I stay here all the time when traveling with my dog. This place is super clean and the staff is excellent."
United States
Dennis
The price is AED 404
AED 448 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn Santee by IHG
Free breakfast

8. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,007 reviews)
"Quiet and safe area, with plenty near the hotel so you don't need to venture far for dinner or needs."
United States
Michael
The price is AED 461
AED 512 total
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn Santee-I-95
Panoramic Tent | Lake view

9. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (97 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
The price is AED 297
AED 340 total
includes taxes & fees
9 Aug - 10 Aug
Bells Marina & Resort
Free daily full breakfast

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (577 reviews)
"It was very clean-might need a few updates to the bathroom tho."
United States
Clara
The price is AED 200
AED 242 total
includes taxes & fees
26 Aug - 27 Aug
Quality Inn & Suites Santee I-95
Breakfast area

11. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,004 reviews)
"Clean comfortable no frills place to stay convenient to dining and interstate"
United States
Ralph
The price is AED 290
AED 322 total
includes taxes & fees
9 Aug - 10 Aug
Travelodge by Wyndham Orangeburg
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

12. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,005 reviews)
"Was a good place to stay"
United States
santa
The price is AED 372
AED 412 total
includes taxes & fees
30 Aug - 31 Aug
Comfort Inn & Suites Santee
Property amenity

13. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (802 reviews)
"Was very nice for the price. Would definitely stay again."
United States
Evie
The price is AED 579
AED 642 total
includes taxes & fees
12 Aug - 13 Aug
SpringHill Suites by Marriott Orangeburg
Suite, 1 King Bed, Accessible, Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

14. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.4 out of 10, (693 reviews)
"The room was clean and comfortable"
United States
Mazzie
The price is AED 219
AED 243 total
includes taxes & fees
30 Aug - 31 Aug
Quality Inn & Suites Orangeburg
Desk, iron/ironing board, WiFi (free), alarm clocks

15. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
6.0 out of 10, (1,002 reviews)
"Clean room and friendly service."
United States
Sandra
The price is AED 203
AED 225 total
includes taxes & fees
12 Aug - 13 Aug
Baymont by Wyndham Orangeburg North
Lobby lounge

16. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (811 reviews)
"Clean rooms, friendly staff, and plenty of parking"
United States
Sherri
The price is AED 403
AED 447 total
includes taxes & fees
9 Aug - 10 Aug
Fairfield Inn by Marriott Orangeburg
Exterior

17. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (827 reviews)
"One of the cleanest hotels we’ve ever stayed in!"
United States
JORDAN
The price is AED 479
AED 532 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn & Suites Orangeburg
Lobby

18. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (583 reviews)
"John, the General Manager, was very welcoming and ensured that we had a wonderful stay."
United States
Kim
The price is AED 250
AED 277 total
includes taxes & fees
23 Aug - 24 Aug
Ramada by Wyndham Santee I-95
Free daily on-the-go breakfast

19. Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg
2.0 star property
Orangeburg
7.0 out of 10, Good, (1,003 reviews)
"It was good and respectful"
United States
Sergio
Super 8 by Wyndham, Orangeburg
Exterior

20. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (847 reviews)
"decent place to stay"
United States
Michael
The price is AED 422
AED 469 total
includes taxes & fees
6 Sep - 7 Sep
Holiday Inn Express & Suites Orangeburg by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Orangeburg County, SC

Showing deals for:14 Aug - 16 Aug

Image gallery for Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Interior

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Bowman
9.8/10Exceptional (34 reviews)
10% off
Price is AED 281
AED 934 total
includes taxes & fees
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Orangeburg County Hotel Reviews

Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

10/10 Excellent
"Excellent accueillant tranquille"
Stephane 1-night trip
Posted 1 hour ago
Spark by Hilton Orangeburg

Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from AED 225 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at AED 225 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Expedia is your one-stop shop for planning the ultimate holiday experience in Orangeburg County. You'll find a wide variety of hotels to select from and handy search filters that make it a breeze to find what you're looking for. Worried about your plans changing? Many of our hotels have flexible cancellation policies, because we know flexibility matters. Get more out of your trip with Expedia Rewards. Join for free today to start collecting points and unlocking membership perks. You'll enjoy instant access to Member Prices, which means you can save 10% or more on select hotels!

Explore a world of travel with Expedia