A serene lake with trees reflecting in the water, surrounded by a forest of tall, slender trees with autumn foliage.

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Check prices for these dates

Next weekend
25 Sep - 27 Sep
In two weeks
2 Oct - 4 Oct

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Our top choices for Orangeburg County hotels

Property amenity

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,002 reviews)
"Property was clean and the breakfast was delicious would stay there again."
United States
Melissa
The price is AED 493
AED 547 total
includes taxes & fees
27 Sep - 28 Sep
Fairfield Inn & Suites by Marriott Santee
Free daily buffet breakfast

2. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (960 reviews)
"Great place to stay!"
United States
Connor
The price is AED 358
AED 398 total
includes taxes & fees
27 Sep - 28 Sep
Tru By Hilton Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

3. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,491 reviews)
"Very quiet, dog friendly, clean, breakfast included."
United States
Yomerys
The price is AED 294
AED 326 total
includes taxes & fees
21 Sep - 22 Sep
Baymont by Wyndham Santee
Seasonal outdoor pool

4. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very good, (1,001 reviews)
"My stay was comfortable and awesome I will be visiting again"
United States
TaNikka
The price is AED 358
AED 398 total
includes taxes & fees
27 Sep - 28 Sep
Spark by Hilton Orangeburg
Snack bar

5. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
"Very much enjoyed our stay. Very friendly staff."
United States
Deborah
The price is AED 419
AED 465 total
includes taxes & fees
4 Oct - 5 Oct
Tru by Hilton Orangeburg
Children's activities

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"I stay here all the time when traveling with my dog. This place is super clean and the staff is excellent."
United States
Dennis
The price is AED 404
AED 448 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Santee by IHG
Exterior

7. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
"Breakfast was good, staff very helpful."
United States
Bonnie
The price is AED 421
AED 468 total
includes taxes & fees
27 Sep - 28 Sep
Best Western Plus Santee Inn
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

8. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,002 reviews)
"Was a good place to stay"
United States
santa
The price is AED 376
AED 417 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn & Suites Santee
Free breakfast

9. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,001 reviews)
"Great location, room and staff."
United States
Herbert
The price is AED 461
AED 511 total
includes taxes & fees
27 Sep - 28 Sep
Hampton Inn Santee-I-95
Panoramic Tent | Lake view

10. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (101 reviews)
"Love it"
United States
Mark
The price is AED 283
AED 325 total
includes taxes & fees
21 Sep - 22 Sep
Bells Marina & Resort
Exterior

11. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (857 reviews)
"Helpful staff, great breakfast buffet"
United States
Jenelyn
The price is AED 404
AED 448 total
includes taxes & fees
27 Sep - 28 Sep
Holiday Inn Express & Suites Orangeburg by IHG
Breakfast area

12. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,000 reviews)
"The place was nice and clean"
United States
Arsenio
The price is AED 290
AED 322 total
includes taxes & fees
27 Sep - 28 Sep
Travelodge by Wyndham Orangeburg
Free daily full breakfast

13. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (592 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
The price is AED 212
AED 255 total
includes taxes & fees
27 Sep - 28 Sep
Quality Inn & Suites Santee I-95
Property amenity

14. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (815 reviews)
"Great Place to Stay!"
United States
Henrietta
The price is AED 401
AED 445 total
includes taxes & fees
27 Sep - 28 Sep
SpringHill Suites by Marriott Orangeburg
Suite, 1 King Bed, Accessible, Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

15. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (704 reviews)
"I like everything."
United States
Ruben
The price is AED 219
AED 243 total
includes taxes & fees
11 Oct - 12 Oct
Quality Inn & Suites Orangeburg
Lobby lounge

16. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (829 reviews)
"Amazing hotel. Always my go to whenever I am staying in Orangeburg. Highly recommended!"
United States
Percy
The price is AED 387
AED 430 total
includes taxes & fees
27 Sep - 28 Sep
Fairfield Inn by Marriott Orangeburg
Exterior

17. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (847 reviews)
"Everything about the hotel was great"
United States
RODERICK V
The price is AED 479
AED 532 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Orangeburg
Lobby lounge

18. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
2.0 star property
Orangeburg
5.8 out of 10, (744 reviews)
"Nice place to stay at an affordable price during our trip to Disney it was our halfway point"
United States
phyllis
The price is AED 215
AED 238 total
includes taxes & fees
27 Sep - 28 Sep
Red Roof Inn Orangeburg
Lobby

19. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (593 reviews)
"The price rate was great"
United States
Stevenson
The price is AED 305
AED 338 total
includes taxes & fees
22 Sep - 23 Sep
Ramada by Wyndham Santee I-95
In-room safe, iron/ironing board, WiFi (free), alarm clocks

20. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (776 reviews)
"Great service"
United States
Kunjan
The price is AED 235
AED 261 total
includes taxes & fees
23 Sep - 24 Sep
Travelodge by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Orangeburg County, SC

Showing deals for:2 Oct - 4 Oct

Image gallery for Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Interior

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Bowman
9.8/10Exceptional (35 reviews)
10% off
Price is AED 281
AED 938 total
includes taxes & fees
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
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Top Orangeburg County Hotel Reviews

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

8/10 Good
"Nice clean room"
LINA 1-night trip
Posted 3 hours ago
Hampton Inn & Suites Orangeburg

Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from AED 238 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at AED 238 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Expedia is your one-stop shop for planning the ultimate holiday experience in Orangeburg County. You'll find a wide variety of hotels to select from and handy search filters that make it a breeze to find what you're looking for. Worried about your plans changing? Many of our hotels have flexible cancellation policies, because we know flexibility matters. Get more out of your trip with Expedia Rewards. Join for free today to start collecting points and unlocking membership perks. You'll enjoy instant access to Member Prices, which means you can save 10% or more on select hotels!

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