Photo by PhotoJoy
Resorts & Hotels with Spas in Panama from AED 355
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Panama Resorts & Hotels with Spas
Pick from 277 Panama Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
8.8 out of 10, Excellent, (1006)
The price is AED 584
AED 642 total
includes taxes & fees
8 Nov - 9 Nov

Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
8.4 out of 10, Very Good, (2297)
The price is AED 448
AED 493 total
includes taxes & fees
5 Dec - 6 Dec

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (622)
The price is AED 720
AED 792 total
includes taxes & fees
5 Dec - 6 Dec

Marriott Panama Hotel
Marriott Panama Hotel
9.0 out of 10, Wonderful, (1012)
The price is AED 493
AED 542 total
includes taxes & fees
7 Nov - 8 Nov

Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1020)
The price is AED 689
AED 758 total
includes taxes & fees
5 Dec - 6 Dec

W Panama
W Panama
9.0 out of 10, Wonderful, (1000)
The price is AED 603
AED 664 total
includes taxes & fees
6 Dec - 7 Dec

Radisson Colon 2,000 Hotel & Casino
Radisson Colon 2,000 Hotel & Casino
8.2 out of 10, Very Good, (800)
The price is AED 322
AED 355 total
includes taxes & fees
22 Nov - 23 Nov

Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (524)
The price is AED 1,107
AED 1,218 total
includes taxes & fees
6 Dec - 7 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Panama Hotel Reviews

Hotel Riu Plaza Panama
10/10 Excellent
Explore a world of travel with Expedia
Top destinations for Resorts & Hotels with Spas in Panama
- Resorts & Hotels with Spas in Bocas del Toro Province
- Resorts & Hotels with Spas in Panamá Province
- Resorts & Hotels with Spas in Coclé
- Resorts & Hotels with Spas in Chiriquí Province
- Resorts & Hotels with Spas in Veraguas
- Resorts & Hotels with Spas in Colón
- Resorts & Hotels with Spas in Los Santos
- Resorts & Hotels with Spas in Herrera
More Hotel Options in Panama
- Hotels with WiFi in Panama
- Hotels with Free Parking in Panama
- Family Hotels in Panama
- Hotels with Bars in Panama
- Beach Hotels in Panama
- Hotels with a Pool in Panama
- Adventure Hotels in Panama
- Business Hotels in Panama
- Shopping Hotels in Panama
- Hotel with a Concierge in Panama
- Hotels with smoking rooms in Panama
- Historic Hotels in Panama
- Casinos in Panama
- Pet-friendly Hotels in Panama
- Hotel Wedding Venues in Panama
- Cheap Hotels in Panama
- Luxury Hotels in Panama
- Romantic Hotels in Panama
- Hotels with Hot Tubs in Panama
- Golf Hotels in Panama
More Themes
- All-inclusive Hotel
- Hotels with Bars
- Beach Hotels
- Boutique Hotels
- Cheap Hotels
- Business Hotels
- Casinos
- Hotel with a Concierge
- Family Hotels
- Hotels with Free Parking
- Golf Hotels
- Historic Hotels
- Hotels with Hot Tubs
- Hotels with an Indoor Pool
- Apartment Hotel
- Hotels with a Lazy River
- Luxury Hotels
- Pet-friendly Hotels
- Hotels with a Pool
- Adventure Hotels
- Romantic Hotels
- Shopping Hotels
- Ski Hotels
- Hotels with smoking rooms
- Green Hotels
- Waterpark Hotels
- Hotels with Waterslides
- Hotel Wedding Venues
- Hotels with WiFi
- Winery Hotels








































