Top Main Street Fort Pierce Hotels

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Our top choices for Main Street Fort Pierce hotels

A pool area with lounge chairs and a hot tub, surrounded by palm trees and a view of the ocean.

1. Hutchinson Island Hotel

3.1 km from Main Street Fort Pierce

Lana

AED 493 total

includes taxes & fees

18 Nov - 19 Nov

A hotel lobby with a large reception desk, multiple seating areas, and a patterned carpet.

2. Fairfield Inn & Suites by Marriott Fort Pierce

7.7 km from Main Street Fort Pierce

Katherine

AED 381 total

includes taxes & fees

25 Oct - 26 Oct

A modern reception area with a long corridor, a reception desk, and a seating area with tables and chairs.

3. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

8.3 km from Main Street Fort Pierce

Rodney

AED 403 total

includes taxes & fees

15 Nov - 16 Nov

4. Hampton Inn & Suites Ft. Pierce

7.9 km from Main Street Fort Pierce

Angela

AED 399 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor seating area with fire feature, stone walls, and a view into the building.

5. Home2 Suites by Hilton Ft. Pierce I-95

7.8 km from Main Street Fort Pierce

JERRY

AED 486 total

includes taxes & fees

31 Oct - 1 Nov

A spacious living area with a grey sofa, a blue sofa, and a wooden accent wall with a flat-screen TV.

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

7.9 km from Main Street Fort Pierce

Tyler

AED 362 total

includes taxes & fees

25 Oct - 26 Oct

A restaurant interior with a bar area, wooden flooring, and multiple seating arrangements.

7. Days Inn & Suites by Wyndham Fort Pierce Midtown

4.5 km from Main Street Fort Pierce

Cynthia

AED 269 total

includes taxes & fees

20 Oct - 21 Oct

A hotel entrance with a welcome sign, a black mat, and two potted plants.

8. At Home Inn

8.2 km from Main Street Fort Pierce

Gregory

AED 210 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with a bed, a sofa, and a small table. There are framed pictures on the wall.

9. Comfort Suites Fort Pierce I-95

7.7 km from Main Street Fort Pierce

Marina

AED 342 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with two beds, a television, a ceiling fan, and a view of the beach.

10. The Royal Inn Beach Hotel Hutchinson Island

3.8 km from Main Street Fort Pierce

Taylor

AED 448 total

includes taxes & fees

19 Oct - 20 Oct

A multi-story hotel with a modern design, featuring a prominent sign for 'Springhill Suites Marriott'.

11. SpringHill Suites Port St. Lucie

17.2 km from Main Street Fort Pierce

Amy

AED 422 total

includes taxes & fees

23 Oct - 24 Oct

A hotel lobby with a reception desk, a chandelier, a clock, and a sofa.

12. Sleep Inn Fort Pierce I-95

7.9 km from Main Street Fort Pierce

Charity

AED 314 total

includes taxes & fees

8 Nov - 9 Nov

A Holiday Inn Express & Suites hotel with a modern design, featuring a prominent entrance, well-maintained landscaping, and a clear view of the sky.

13. Holiday Inn Express & Suites Port St. Lucie West by IHG

17.1 km from Main Street Fort Pierce

AEON

AED 453 total

includes taxes & fees

25 Oct - 26 Oct

A gym with treadmills, elliptical machines, and a red exercise ball.

14. Hampton Inn & Suites Port St. Lucie, West

17.4 km from Main Street Fort Pierce

Ahim

AED 399 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, a dining area with bar stools, and a large TV mounted on the wall.

15. Hampton Inn & Suites Vero Beach Downtown

22.1 km from Main Street Fort Pierce

Cameron

AED 536 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

16. Staybridge Suites Vero Beach by IHG

24.1 km from Main Street Fort Pierce

Michelle

AED 510 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, seating area, and a hallway leading to other rooms.

17. Days Inn & Suites by Wyndham Fort Pierce I-95

7.8 km from Main Street Fort Pierce

Carlton

AED 246 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a large bed, a desk, a chair, a television, and a framed picture on the wall.

18. Red Roof Inn Ft Pierce

4.6 km from Main Street Fort Pierce

Rhonise

AED 296 total

includes taxes & fees

19 Oct - 20 Oct

A clear blue swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a gazebo.

19. Best Western Port St. Lucie

14 km from Main Street Fort Pierce

BRIAN

AED 370 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with a fire pit, red and black wicker furniture, and string lights.

20. Residence Inn by Marriott Port St. Lucie

17.8 km from Main Street Fort Pierce

Eduardo

AED 453 total

includes taxes & fees

25 Oct - 26 Oct

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Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.

A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, McKee Botanical Garden and Avalon State Park are some notable places to visit nearby.

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Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Harbor Branch Ocean Discovery Center and McKee Botanical Garden.

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A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

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A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

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A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

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Top Main Street Fort Pierce Hotel Reviews

Hutchinson Island Hotel

10/10 Excellent

"Friendly staff. Clean facilities"

La Quinta Inn & Suites by Wyndham Ft. Pierce

8/10 Good

"The guest services representative was professional, efficient, and quick, making for a pleasant check-in experience. The room was clean, comfortable, and well-appointed, with attractive artwork and tasteful furniture. The quartz bathroom countertop was beautiful, and the mirror was a standout feature. The faucet could use an update or replacement. The beds and pillows were both very comfortable, contributing to an enjoyable stay. A couple of minor details are worth noting: the shower area has a very bright AC indicator light, so light-sensitive guests may want to bring something to cover it. The curtains also let in a small amount of outside light. Breakfast offered a good variety, including haddock, hash browns, bacon, waffles, and an assortment of continental options. Coffee, juices, and hot water for tea were available. The coffee was a little mild, but the good-quality creamers helped improve it. Overall, this was a very enjoyable stay, with a clean and comfortable room, professional service, and a satisfying breakfast. With a few minor updates, the experience could be even better."

Frequently asked questions

What is Main Street Fort Pierce like?

Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Sunrise Theater and Fort Pierce Farmer's Market as part of your Main Street Fort Pierce travel plans.

How many hotels can I expect to find in Main Street Fort Pierce?

Book one of Expedia's 7 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.

If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.

Where can I learn more about changing or cancelling my trip to Main Street Fort Pierce?

For additional details about changing or cancelling your trip to Main Street Fort Pierce, head over to our customer service page.

What is there to do in this Fort Pierce neighborhood?

Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce Farmer's Market and Fort Pierce City Marina are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables, and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.

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Our top choices for Main Street Fort Pierce hotels

1. Hutchinson Island Hotel

2. Fairfield Inn & Suites by Marriott Fort Pierce

3. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

4. Hampton Inn & Suites Ft. Pierce

5. Home2 Suites by Hilton Ft. Pierce I-95

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

7. Days Inn & Suites by Wyndham Fort Pierce Midtown

8. At Home Inn

9. Comfort Suites Fort Pierce I-95

10. The Royal Inn Beach Hotel Hutchinson Island

11. SpringHill Suites Port St. Lucie

12. Sleep Inn Fort Pierce I-95

13. Holiday Inn Express & Suites Port St. Lucie West by IHG

14. Hampton Inn & Suites Port St. Lucie, West

15. Hampton Inn & Suites Vero Beach Downtown

16. Staybridge Suites Vero Beach by IHG

17. Days Inn & Suites by Wyndham Fort Pierce I-95

18. Red Roof Inn Ft Pierce

19. Best Western Port St. Lucie

20. Residence Inn by Marriott Port St. Lucie

Where to stay in Main Street Fort Pierce

Lakewood Park

Spanish Lakes Country Club Village

Spanish Lakes Fairways

Meadowood

Panther Woods

Top Main Street Fort Pierce Hotel Reviews

Hutchinson Island Hotel

Frequently asked questions