The Best Business Hotels in Duncan, SC from AED 279 in 2026 | Expedia

A park with a grassy field, a lake, and a road.

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Check availability on Duncan Business Hotels

Tonight

15 Oct - 16 Oct

Tomorrow

16 Oct - 17 Oct

This weekend

16 Oct - 18 Oct

Next weekend

23 Oct - 25 Oct

Our top choices for Duncan business-friendly hotels

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

A vending machine area with snacks and beverages, and a display of green apples.

A modern lounge area with a green sofa, multiple tables, chairs, and a flat-screen TV.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass facade and a well-lit exterior.

1. Home2 Suites by Hilton Duncan

Duncan

United States

Marina

AED 450

AED 499 total

includes taxes & fees

1 Nov - 2 Nov

A modern dining area with multiple tables and chairs, a large window, and a ceiling with recessed lighting.

A modern interior with a fireplace, seating, and a wooden accent wall.

Reception

A hotel room with a flat-screen TV, a desk with a chair, a bed, and a microwave.

2. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

United States

Nilda

AED 412

AED 457 total

includes taxes & fees

5 Nov - 6 Nov

A modern living room with a fireplace, a flat-screen TV, and a dining area with chairs and a table.

A modern kitchen with a central island, bar stools, and pendant lighting.

A reception area with a wooden reception desk, a refrigerator stocked with beverages, and shelves with snacks.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

3. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Duncan

United States

Joseph

AED 457

AED 514 total

includes taxes & fees

26 Oct - 27 Oct

A hotel room with two beds, a desk, a chair, a TV, and a window.

A Holiday Inn Express & Suites hotel with a covered entrance, multiple windows, and a parking lot.

A buffet with labeled containers of turkey sausage and cookies.

A coffee station with two coffee machines and a display of coffee products.

4. Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG

Duncan

United States

Hernan

AED 360

AED 405 total

includes taxes & fees

15 Nov - 16 Nov

A modern kitchen with a large wooden table and brown leather chairs, a microwave, and a coffee machine.

A hotel room with two beds, a wooden headboard, a nightstand, a lamp, and a window with a view.

A compact kitchen with white cabinets, a microwave, a sink, and a flat-screen TV.

5. Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

Duncan

United States

Laura Michelle

AED 380

AED 422 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a large bed, bedside tables, a window with curtains, and a built-in heater.

A hotel reception area with a wooden reception desk, a sofa, and a coffee table. There are potted plants and a large window with a view.

A two-story house with a stone facade, a stone walkway, and a well-maintained lawn.

A sunlit room with a sofa, a coffee table with a vase of flowers, a large window with curtains, and a refrigerator.

6. Microtel Inn by Wyndham Duncan/Spartanburg

Duncan

United States

Tim

AED 261

AED 290 total

includes taxes & fees

18 Oct - 19 Oct

A modern restaurant with a bar area, dining tables, and chairs. There are framed pictures on the walls, a television, and various food and drink displays.

A hotel room with two beds, a large window with curtains, a wall-mounted artwork, and a carpeted floor.

A workspace with a desktop computer, a chair, and a wall-mounted plant arrangement.

A modern reception area with a wavy-textured counter, a digital check-in kiosk, and a view of the outdoors through a large window.

7. Quality Inn Duncan - Spartanburg West

Duncan

United States

Caitlyn

AED 264

AED 305 total

includes taxes & fees

21 Oct - 22 Oct

A hotel room with a bed, a sofa, a desk with a computer, a television, and a bathroom visible through an open door.

A modern bathroom with a white bathtub, a vanity with a sink, and a large mirror.

A row of white motel buildings with balconies, a Baymont sign, and a Coca-Cola vending machine.

A modern hotel lobby with a reception desk, dining area, and seating.

8. Baymont by Wyndham Duncan/Spartanburg

Duncan

United States

Sandra

AED 258

AED 286 total

includes taxes & fees

19 Oct - 20 Oct

View all properties

Top Duncan Hotel Reviews

Hyatt Regency Greenville

Hyatt Regency Greenville

10/10 Excellent

"Such a wonderful stay!!! The hotel was fantastic and in such a great location! The staff was incredibly welcoming, and the bartender downstairs was so much fun! One little moment that really stood out was when it started raining and I mentioned that I wished I had an umbrella. Without hesitation, one of the staff members offered me an extra one he had. It’s those little gestures that make such a difference! Just an all-around amazing experience for my first visit to Greenville! We will definitely be back!"