Eastern Tennessee Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AED 148 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Eastern Tennessee

Find the best Eastern Tennessee areas and neighborhoods for the activities you enjoy most. Learn more about Eastern Tennessee
Fall at Honey Creek Loop Trail at Big South Fork National Recreation Area in central Tennessee

Big Creek

While visiting Big Creek, you might make a stop by sights like Whitman Hollow Marina and Norris Lake.

Find hotels in Big Creek

Find the Best Eastern Tennessee Vacation Packages

Eastern Tennessee Hotel Deals

Best Western Plaza Inn

Best Western Plaza Inn

2.5 out of 5
3755 Parkway Pigeon Forge TN
Fully refundableReserve now, pay when you stay
The price is AED 257 per night from Feb 11 to Feb 12
AED 257
AED 288 total
11 Feb - 12 Feb
includes taxes & fees
8.8/10 Excellent! (2,178 reviews)
Great!

Reviewed on 2 February 2026

Best Western Plaza Inn
Sonesta Select Chattanooga Hamilton Place

Sonesta Select Chattanooga Hamilton Place

3 out of 5
2210 Bams Dr Chattanooga TN
Fully refundableReserve now, pay when you stay
The price is AED 261 per night from Feb 15 to Feb 16
AED 261
AED 306 total
15 Feb - 16 Feb
includes taxes & fees
8.6/10 Excellent! (219 reviews)
Clean room and staff was very helpful

Reviewed on 8 February 2026

Sonesta Select Chattanooga Hamilton Place
Comfort Inn & Suites Knoxville West

Comfort Inn & Suites Knoxville West

2.5 out of 5
7737 Kingston Pike Knoxville TN
Fully refundableReserve now, pay when you stay
The price is AED 291 per night from Feb 16 to Feb 17
AED 291
AED 344 total
16 Feb - 17 Feb
includes taxes & fees
8/10 Very Good! (955 reviews)
Clean room and courteous staff

Reviewed on 8 February 2026

Comfort Inn & Suites Knoxville West
See all 25,882 properties in Eastern Tennessee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Eastern Tennessee

Harrahs Cherokee Casino

Harrahs Cherokee Casino

Why not roll the dice by visiting Harrahs Cherokee Casino where you can enjoy the games and entertainment of this top casino in Cherokee? Discover the mountain views and casinos in this quaint area.

Harrahs Cherokee Casino
LeConte Center At Pigeon Forge

LeConte Center at Pigeon Forge

Learn about the events happening at LeConte Center at Pigeon Forge during your trip to Pigeon Forge. Amble around this family-friendly area's riverfront or experience its acclaimed theater scene.

LeConte Center at Pigeon Forge
Great Smoky Mountains at sun rise, with clouds in valley

Great Smoky Mountains National Park Headquarters

Great Smoky Mountains National Park Headquarters is just one of the places to see in Gatlinburg, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or discover the beautiful waterfalls in this romantic area.

Great Smoky Mountains National Park Headquarters

Frequently asked questions

How do I find cheap flights to Eastern Tennessee that have flexible change policies?
It's as easy as counting 1-2-3 with Expedia. Step 1: Type in your preferred dates and destination and click on the "Search" button. Next step? Check the "No change fee" box directly underneath the "Flexible change policies" subheading to the left of your screen. Step 3. Score your cheap and flexible airfare to Eastern Tennessee.
Which airlines fly to Eastern Tennessee?
Book a ticket with any of these top airlines and get set to say yes to new adventures in Eastern Tennessee:

  • American Airlines - 1,180 flights to or near Eastern Tennessee each month, including 651 flights to McGhee Tyson Airport (TYS) and 338 to Chattanooga Metropolitan Airport (CHA) per month.
  • Delta - 853 flights to or near Eastern Tennessee each month, including 398 flights to McGhee Tyson Airport (TYS) and 312 to Chattanooga Metropolitan Airport (CHA) per month.
  • United Airlines - 446 flights to or near Eastern Tennessee each month, including 364 flights to McGhee Tyson Airport (TYS) and 82 to Chattanooga Metropolitan Airport (CHA) per month.

How can I find cheap tickets to Eastern Tennessee?
You'll always nab a terrific deal with Expedia, but our "flexible dates" search function makes it even easier. Enter your preferred flight date, then tick the flexible dates box above to reveal the cheapest prices for nearby days. was the best price for a flight to Eastern Tennessee in the last seven days.
How much is a flight to Eastern Tennessee?
In the last seven days, round-trip tickets to Eastern Tennessee sold for as little as and reached a maximum price of . For one-way trips taking off from (), the cheapest seat during this same period was .
What are the most popular airports to fly into in Eastern Tennessee?
Touch down at any one of these leading airports in Eastern Tennessee and you'll be perfectly placed to discover all that this region has to offer:

  • McGhee Tyson Airport (TYS) - 1,600 flights per month.
  • Chattanooga Metropolitan Airport (CHA) - 758 flights per month.
  • Tri-Cities Regional Airport (TRI) - 342 flights per month.

When is the cheapest time to fly to Eastern Tennessee?
Leave for Eastern Tennessee early in the week and you'll usually be rewarded with lower fares. Tuesday is generally the cheapest day to fly out, with Monday a close second. If you want to avoid the most expensive flights, give Saturdays a wide berth.
How much is a plane ticket to Eastern Tennessee?
In the last seven days, flights to Eastern Tennessee ranged from to .
What months are the cheapest to book a flight to Eastern Tennessee?
To land a great deal to Eastern Tennessee, try to book during the month of February when prices are at their lowest. When's the most expensive time? In the U.S, it's December.
How long is a flight to Eastern Tennessee?
Your flight to Eastern Tennessee could be short or it could be long depending on where your point of departure is. Before you load your laptop with TV shows and podcasts, take a look at the average flight times for these busy domestic routes:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to McGhee Tyson Airport (TYS) - 57 minutes
  • Charlotte, NC (CLT-Charlotte-Douglas Intl.) to McGhee Tyson Airport (TYS) - 1 hour and 14 minutes
  • New York, NY (LGA-LaGuardia) to McGhee Tyson Airport (TYS) - 2 hours and 22 minutes

What are the best things to do in Eastern Tennessee?

  • Brimming with culture and atmosphere, Tri-Cities is the ideal base for your Eastern Tennessee vacation. Pay a visit to renowned attractions like Bristol Motor Speedway, hit up the stores or eat and drink your way around some of this city's fabulous restaurants. The choice is yours!
  • When thinking about which items of clothing to take on your trip, bear in mind that Tri-Cities has an oceanic climate. To give you a clearer picture of what to expect while you're there, check out the weather conditions before you jet off.
  • When you'd like to get out and explore more of this wonderful region, grab one of our cheap car rentals and make tracks to Nashville. It's 386 kilometers to the west of Tri-Cities and is also the home of leading tourist attractions, such as Old Hickory Lake.

What is the best time to go to Eastern Tennessee?
If you like your days to sizzle like an outdoor barbecue, plan your trip to Eastern Tennessee anytime after June 20. This is the start of summer, when temperatures typically vary between 18ºC (64ºF) and 31ºC (88ºF) in the main city of Knoxville. June, July and October are the most popular months to tour around this destination.