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Compare 128 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Quality Inn Mullins - Marion
Quality Inn Mullins - Marion
7.6 out of 10, Good, (334)
The price is AED 337
AED 368 total
includes taxes & fees
16 Jun - 17 Jun

Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHG
9.4 out of 10, Exceptional, (479)
The price is AED 466
AED 508 total
includes taxes & fees
8 Jun - 9 Jun

Best Western Executive Inn
Best Western Executive Inn
8.2 out of 10, Very Good, (853)
The price is AED 375
AED 408 total
includes taxes & fees
23 Jun - 24 Jun

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
8.6 out of 10, Excellent, (1002)
The price is AED 448
AED 502 total
includes taxes & fees
8 Jun - 9 Jun

The Inn at the Crossroads
The Inn at the Crossroads
9.4 out of 10, Exceptional, (720)
The price is AED 644
AED 722 total
includes taxes & fees
8 Jun - 9 Jun

Quality Inn & Suites
Quality Inn & Suites
7.2 out of 10, Good, (153)
The price is AED 426
AED 478 total
includes taxes & fees
2 Jul - 3 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Effingham
Check out the local area in Effingham as you venture to sights like Lynches River State Park.
More cheap stays in Effingham
More cheap stays in Effingham

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
The price is AED 241 per night from Jun 8 to Jun 9
AED 241
AED 270 total
includes taxes & fees
8 Jun - 9 Jun
8.6/10 Excellent! (2,213 reviews)
Recent reviews of Effingham hotels
Recent reviews of Effingham hotels

Howard Johnson by Wyndham Florence
5/5 Excellent
"This is a highway exit hotel and I don’t usually expect a lot. However, the staff was very nice and expedient with our check in/check out process. As a traveling professional I have become very acclimated to what I will find in/from hotels. During this trip this was our first over night and the experience was a very good one. Rooms were clean and spacious. The only down side was that the walls were thin and we could hear everything in the room next door. But overall it was a good experience. I would stay again."
A verified traveler stayed at Howard Johnson by Wyndham Florence
Posted 21 hours ago
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Stay near popular Effingham attractions
- Hotels near Darlington Raceway
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Francis Marion University
- Hotels near Mcleod Regional Medical Center
- Hotels near Florence Motor Speedway
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence National Cemetery
- Hotels near Florence Museum
- Hotels near The Traces Golf Club
- Hotels near Beaver Creek Golf Club
- Hotels near Lions Park
- Hotels near Florence Veterans Park
- Hotels near Oakdale Country Club
- Hotels near Moore Farms Botanical Garden
- Hotels near Woods Bay State Park
- Hotels near The Country Club at Lake City
- Hotels near Ronald E. McNair Life History Center
- Hotels near Columns Plantation
Hotels near Effingham Airports
Other Hotels near Effingham, South Carolina
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Explore more hotels
- Country Inn & Suites by Radisson, Florence, SC
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
- Tru by Hilton Florence I-95
- The Inn at the Crossroads
- Aloft Florence
- Hampton Inn & Suites Florence Center
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Hampton Inn & Suites Florence-North-I-95
- TownePlace Suites by Marriott Florence
- Comfort Suites Florence I-95
- Courtyard by Marriott Florence
- Hilton Garden Inn Florence