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Check availability on Florence Luxury Hotels

Top Florence Luxury Hotels

Rooftop terrace
The Mantissa Hotel

The Mantissa Hotel

3.0 star property
Hartsville
  • Breakfast included
  • Parking included
  • Free WiFi
  • Restaurant
  • Air conditioning
  • Gym
9.2 out of 10, Wonderful, (268)
Sumptuous Select Comfort beds with premium linens anchor each spacious suite, complete with full kitchens and separate living areas. Steps from Hartsville Museum, this intimate 17-room hotel pampers guests with complimentary breakfast and a rooftop terrace overlooking the charming downtown.
The price is AED 595
AED 666 total
includes taxes & fees
20 Nov - 21 Nov
The Mantissa Hotel
Exterior
Days Inn by Wyndham Dillon

Days Inn by Wyndham Dillon

2.0 star property
Dillon
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
5.4 out of 10, (853)
Spacious, immaculately maintained rooms provide a serene retreat after exploring nearby Dillon highlights. Friendly staff consistently deliver exceptional service, creating a peaceful luxury experience complemented by refreshing swims in the seasonal outdoor pool.
The price is AED 203
AED 227 total
includes taxes & fees
23 Nov - 24 Nov
Days Inn by Wyndham Dillon
Bar (on property)
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
Florence
  • Full-service spa
8.8 out of 10, Excellent, (593)
Housed in a beautifully refurbished warehouse, this sophisticated retreat pairs historic charm with modern indulgence. Couples can enjoy specialized spa treatments including hot stone massages, aromatherapy, and detox wraps. Premium dining at Victors Bistro completes the refined experience.
The price is AED 479
AED 536 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Florence, Tapestry Collection by Hilton
Free daily on-the-go breakfast
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2.0 star property
Florence
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
6.8 out of 10, (1001)
Seasonal outdoor pool beckons travelers to this welcoming Florence motel, where friendly staff earn consistent praise. Garden spaces provide tranquil relaxation after exploring nearby dining options, with convenient amenities and pet-friendly accommodations enhancing every stay.
The price is AED 225
AED 252 total
includes taxes & fees
28 Nov - 29 Nov
Days Inn by Wyndham Florence/I-95 North
Breakfast area
Baymont Inn & Suites Florence by Wyndham

Baymont Inn & Suites Florence by Wyndham

2.5 star property
Florence
  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
5.6 out of 10, (1000)
Seasonal outdoor relaxation awaits at this Florence airport hotel. Guests appreciate pillowtop comfort in stylish rooms, friendly staff service, and convenient amenities including a fitness center. Located just 1 mile from the tennis center and 3 miles from local museums.
Baymont Inn & Suites Florence by Wyndham
Lobby
Clarion Inn & Suites Florence - Darlington

Clarion Inn & Suites Florence - Darlington

2.5 star property
Florence
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Restaurant
4.4 out of 10, (289)
Luxurious rainfall showers and deep soaking tubs await in each elegantly appointed room featuring premium bedding and sofa beds. Guests savor complimentary breakfast before lounging by the seasonal outdoor pool or maintaining fitness routines in the well-equipped center.
The price is AED 199
AED 223 total
includes taxes & fees
28 Nov - 29 Nov
Clarion Inn & Suites Florence - Darlington
Desk, laptop workspace, free cribs/infant beds, free WiFi
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2.0 star property
Florence
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • 24/7 front desk
  • Extra beds/cribs
6.8 out of 10, (1002)
Spacious, clean accommodations welcome travelers and their pets at this quiet hotel near Florence Civic Center. Premium TV channels and laptop-friendly workspaces enhance each room. Attentive staff provides excellent service throughout the conveniently located property.
The price is AED 206
AED 231 total
includes taxes & fees
16 Nov - 17 Nov
Red Roof Inn Florence - Civic Center
Desk, iron/ironing board, free WiFi, bed sheets
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
Florence
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
6.8 out of 10, (1002)
Luxurious tranquility defines this well-appointed retreat where attentive staff exceed expectations. Spacious rooms feature premium amenities while the seasonal outdoor pool provides refreshing respite after exploring nearby Magnolia Mall and Florence Civic Center.
The price is AED 237
AED 266 total
includes taxes & fees
16 Nov - 17 Nov
Days Inn by Wyndham Florence Near Civic Center
Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi
Quality Inn & Suites

Quality Inn & Suites

2.5 star property
Dillon
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
7.2 out of 10, Good, (751)
Luxurious relaxation awaits at this serene countryside retreat. Indulgent amenities include a refreshing swimming pool, complimentary gourmet breakfast buffet, and plush rooms with modern conveniences. Professional staff provides attentive service, ensuring a sophisticated stay for discerning travelers.
The price is AED 267
AED 299 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn & Suites
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property
Florence
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
7.8 out of 10, Good, (1247)
Plush comfort defines this centrally located Florence retreat. Guests rave about exceptionally clean rooms with luxury bedding, a beautiful seasonal outdoor pool often enjoyed in peaceful solitude, and consistently friendly staff delivering excellent service throughout each stay.
The price is AED 312
AED 350 total
includes taxes & fees
12 Dec - 13 Dec
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Florence

Florenceand its attractions for luxury travelers

Florence, South Carolina, offers a blend of Southern charm and luxurious experiences perfect for travelers. Begin your exploration at the Florence Museum, where you can admire a diverse collection of Southern art and historical artifacts in a beautifully designed space. For a taste of local culture, the Magnolia Mall provides a shopping experience featuring upscale retailers and boutiques, ideal for indulging in some retail therapy. Nature lovers will appreciate a stroll through the serene gardens at the Florence County Museum, where the exhibits are complemented by picturesque outdoor spaces. If you're seeking adventure, the nearby Lynches River County Park offers kayaking and hiking opportunities that allow you to connect with the natural beauty of the region. For accommodations, the area around the historic downtown is particularly appealing, with luxury hotels that provide a blend of modern comfort and Southern hospitality. Enjoy spacious suites, gourmet dining options, and attentive service, ensuring a pampered stay as you explore Florence's attractions.

Top Florence Hotel Reviews

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

10/10 Excellent
"Spacious, clean, peaceful, courteous staff. Nice get-away from sick, aggravating parents."
Larissa 3-night trip
Posted 10 days ago
Days Inn by Wyndham Florence/I-95 North

Explore a world of travel with Expedia

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you're in the area, you might want to stop by Florence Veterans Park and Florence Civic Center.
How can I get around Florence?
It's easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.