A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Adults Only Resorts & Hotels

Our top choices for Florida Keys adults-only hotels

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,049 reviews)
"The hotel has a perfect location. We enjoyed the breakfast. It was clean and the staff was amazing."
United States
david
The price is AED 393
AED 522 total
includes taxes & fees
11 Aug - 12 Aug
Duval House

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (445 reviews)
"Great stay"
United States
Matthew
The price is AED 429
AED 530 total
includes taxes & fees
20 Jul - 21 Jul
Douglas House - Adults Only

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,005 reviews)
"We loved our one night stay here! Everything was very clean and the staff was very helpful in letting us do self check-in since we arrived after 5:30. The breakfast was perfect and I enjoyed the views in the courtyard."
United States
Elizabeth
The price is AED 442
AED 589 total
includes taxes & fees
15 Jul - 16 Jul
The Grand Guesthouse

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,007 reviews)
"Charming old home with history around every corner. The pool is splendid, and it’s easy to forget the world exists as you stare off to sea."
United States
Elizabeth Anne
The price is AED 585
AED 1,123 total
includes taxes & fees
26 Jul - 27 Jul
Southernmost House - Adult Exclusive

The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Old Town Key West
9.0 out of 10, Wonderful, (1,008 reviews)
"Great place"
United States
Andrea
The price is AED 492
AED 718 total
includes taxes & fees
2 Aug - 3 Aug
The Cabana Inn Key West - Adults Only

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,006 reviews)
"Loved the location, breakfast and clean room. Staff, Drew, very friendly and helpful. Will definitely stay here again."
United States
Richard
The price is AED 392
AED 441 total
includes taxes & fees
13 Jul - 14 Jul
L'Habitation Guest House

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,165 reviews)
"Great stay highly recommended"
United States
Lindsay
The price is AED 437
AED 614 total
includes taxes & fees
13 Jul - 14 Jul
Heron House - Adult Only

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very Good, (1,412 reviews)
"Wonderful place"
United States
Clarice
The price is AED 449
AED 670 total
includes taxes & fees
16 Jul - 17 Jul
The Southernmost Inn - Adults Only

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
8.2 out of 10, Very Good, (1,010 reviews)
"Nice place to stay!"
United States
michael
The price is AED 327
AED 533 total
includes taxes & fees
13 Jul - 14 Jul
NYAH Key West - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,007 reviews)
"Wonderful place and staff!"
United States
William
The price is AED 704
AED 792 total
includes taxes & fees
15 Jul - 16 Jul
Orchid Key Inn - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

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