A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Adults Only Resorts & Hotels

Our top choices for Florida Keys adults-only hotels

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (333 reviews)
"Very relaxing and low key spot with lots of fun outdoor amenities, staff got us into our room early and were super helpful and friendly. Would stay here again."
United States
Michelle
The price is AED 555
AED 728 total
includes taxes & fees
21 Jul - 22 Jul
Kona Kai Resort and Gallery - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Old Town Key West
10.0 out of 10, Exceptional, (1,022 reviews)
"Great stay! Great location and friendly, helpful staff. Loved our stay here! Would recommend."
United States
Linda
The price is AED 814
AED 916 total
includes taxes & fees
20 Jul - 21 Jul
Almond Tree Inn Hotel - Adults Only

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,004 reviews)
"Great location and beautiful property. I appreciate the parking which comes at a premium in Key West and the two swimming pools. Just enough off the beaten path to feel comfortable."
United States
Darrell
The price is AED 830
AED 1,140 total
includes taxes & fees
2 Aug - 3 Aug
The Marquesa Hotel

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,008 reviews)
"Wonderful place and staff!"
United States
William
The price is AED 814
AED 916 total
includes taxes & fees
20 Jul - 21 Jul
Orchid Key Inn - Adults Only

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very Good, (1,417 reviews)
"Wonderful place"
United States
Clarice
The price is AED 398
AED 613 total
includes taxes & fees
20 Jul - 21 Jul
The Southernmost Inn - Adults Only

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,001 reviews)
"The room was amazing with a great kitchen, and very clean. The staff was very professional and friendly and the breakfast delicious."
United States
Alina
The price is AED 512
AED 1,040 total
includes taxes & fees
16 Aug - 17 Aug
Southernmost House - Adult Exclusive

Bahia Bay Resort

Bahia Bay Resort
2.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (182 reviews)
"Amazing stay! Im so happy we found this cute romantic little spot"
United States
Laura
The price is AED 493
AED 554 total
includes taxes & fees
22 Jul - 23 Jul
Bahia Bay Resort

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (452 reviews)
"Great stay"
United States
Matthew
The price is AED 486
AED 601 total
includes taxes & fees
21 Jul - 22 Jul
Douglas House - Adults Only

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,001 reviews)
"The room was clean and quaint, the staff was very friendly, the property was beautiful and the location was excellent. Would love to stay again!"
United States
Jason
The price is AED 572
AED 735 total
includes taxes & fees
20 Jul - 21 Jul
The Grand Guesthouse

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
8.2 out of 10, Very Good, (1,000 reviews)
"Great spot, would stay again"
United States
Ben
The price is AED 426
AED 645 total
includes taxes & fees
20 Jul - 21 Jul
NYAH Key West - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

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