A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Adults Only Resorts & Hotels

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Our top choices for Florida Keys adults-only hotels

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (438 reviews)
"Great stay"
United States
Matthew
The price is AED 429
AED 530 total
includes taxes & fees
6 Jul - 7 Jul
Douglas House - Adults Only

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,000 reviews)
"Fresh continental breakfast, clean room, close to everything."
United States
BOBBY J.
The price is AED 585
AED 1,123 total
includes taxes & fees
15 Jul - 16 Jul
Southernmost House - Adult Exclusive

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,047 reviews)
"Great location and clean rooms. Breakfast staff is so sweet! Will stay here again for sure!!"
United States
Wendy S
The price is AED 405
AED 535 total
includes taxes & fees
5 Jul - 6 Jul
Duval House

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,000 reviews)
"we had a great stay, rented bikes"
United States
Duncan
The price is AED 442
AED 589 total
includes taxes & fees
6 Jul - 7 Jul
The Grand Guesthouse

Tropical Inn

Tropical Inn
3.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (414 reviews)
"Very friendly staff and a prime location."
United States
Akhenaton
The price is AED 689
AED 867 total
includes taxes & fees
6 Jul - 7 Jul
Tropical Inn

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (999 reviews)
"Loved the location, breakfast and clean room. Staff, Drew, very friendly and helpful. Will definitely stay here again."
United States
Richard
The price is AED 459
AED 517 total
includes taxes & fees
5 Jul - 6 Jul
L'Habitation Guest House

The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Old Town Key West
9.0 out of 10, Wonderful, (1,007 reviews)
"Great place"
United States
Andrea
The price is AED 454
AED 676 total
includes taxes & fees
6 Jul - 7 Jul
The Cabana Inn Key West - Adults Only

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
8.2 out of 10, Very Good, (1,006 reviews)
"Nice place to stay!"
United States
michael
The price is AED 311
AED 515 total
includes taxes & fees
7 Jul - 8 Jul
NYAH Key West - Adults Only

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (149 reviews)
"The staff and other guests were very friendly. The room was spacious and the bed was comfortable. "
United States
Annette
The price is AED 724
AED 963 total
includes taxes & fees
2 Aug - 3 Aug
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very Good, (1,401 reviews)
"Lovely hotel very comfortable room. Great pool facilities. Helpful staff. Would recommend this hotel."
Australia
Sharon
The price is AED 429
AED 648 total
includes taxes & fees
6 Jul - 7 Jul
The Southernmost Inn - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

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