Find Adults Only Resorts & Hotels in Florida Keys

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Check availability on Florida Keys Adults Only Resorts & Hotels

Our top choices for Florida Keys adults-only hotels

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.2 out of 10, Very Good, (1203)
"Great stay! "
United States
Mary Ellen
The price is AED 400
AED 616 total
includes taxes & fees
16 Dec - 17 Dec
The Southernmost Inn - Adults Only

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1003)
"Had a great stay"
United States
Bren Albert
The price is AED 547
AED 695 total
includes taxes & fees
15 Dec - 16 Dec
Duval House

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.0 out of 10, Wonderful, (1141)
"Loved the setup of the hotel and great location! "
United States
Rachel
The price is AED 438
AED 615 total
includes taxes & fees
17 Dec - 18 Dec
Heron House - Adult Only

The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Old Town Key West
8.8 out of 10, Excellent, (1003)
"Rooms are clean, staff was friendly and pool was refreshing. "
United States
Wendy
The Cabana Inn Key West - Adults Only

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
7.8 out of 10, Good, (1005)
"Great little hotel in the heart of Old Town."
United States
Robert
The price is AED 1,249
AED 1,570 total
includes taxes & fees
2 Jan - 3 January 2026
NYAH Key West - Adults Only

Heron House Court - Adult Only

Heron House Court - Adult Only
3.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1004)
"Great staff, very friendly. Oerfect location, short walk to Duval, but far enough to get sleep. "
United States
Chandler
The price is AED 1,021
AED 1,288 total
includes taxes & fees
4 Jan - 5 January 2026
Heron House Court - Adult Only

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (920)
"Great place close to all. Manager was very helpful in recommending how to get around the island, what to do and where to eat."
United States
Robert
The price is AED 500
AED 563 total
includes taxes & fees
14 Dec - 15 Dec
L'Habitation Guest House

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1000)
"Great stay"
United States
Ginger
The Grand Guesthouse

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Old Town Key West
10.0 out of 10, Exceptional, (1003)
"Very nice & peaceful with a wonderful staff. Our second time staying here"
United States
Sandra
The price is AED 915
AED 1,030 total
includes taxes & fees
16 Dec - 17 Dec
Almond Tree Inn Hotel - Adults Only

Southernmost House

Southernmost House
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1002)
"Great place with excellent staff. "
United States
Willie
The price is AED 988
AED 1,453 total
includes taxes & fees
16 Dec - 17 Dec
Southernmost House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

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