A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Adults Only Resorts & Hotels

Our top choices for Florida Keys adults-only hotels

The National Hotel Miami Beach

The National Hotel Miami Beach
4.5 star property
South Beach
9.0 out of 10, Wonderful, (1,791 reviews)
"Great place to stay"
United States
kelsey
The price is AED 493
AED 792 total
includes taxes & fees
3 Aug - 4 Aug
The National Hotel Miami Beach

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,007 reviews)
"Nice spot to stay in Key West. Good location, nice pool, and good breakfast. "
United States
Brendan
The price is AED 585
AED 1,123 total
includes taxes & fees
26 Jul - 27 Jul
Southernmost House - Adult Exclusive

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (445 reviews)
"Great stay"
United States
Matthew
The price is AED 486
AED 601 total
includes taxes & fees
12 Jul - 13 Jul
Douglas House - Adults Only

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,048 reviews)
"The hotel has a perfect location. We enjoyed the breakfast. It was clean and the staff was amazing."
United States
david
The price is AED 389
AED 517 total
includes taxes & fees
13 Jul - 14 Jul
Duval House

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,004 reviews)
"we had a great stay, rented bikes"
United States
Duncan
The price is AED 442
AED 589 total
includes taxes & fees
15 Jul - 16 Jul
The Grand Guesthouse

The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Old Town Key West
9.0 out of 10, Wonderful, (1,008 reviews)
"Great place"
United States
Andrea
The price is AED 473
AED 697 total
includes taxes & fees
12 Jul - 13 Jul
The Cabana Inn Key West - Adults Only

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,165 reviews)
"Great stay highly recommended"
United States
Lindsay
The price is AED 437
AED 614 total
includes taxes & fees
12 Jul - 13 Jul
Heron House - Adult Only

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
8.2 out of 10, Very Good, (1,010 reviews)
"Nice place to stay!"
United States
michael
The price is AED 327
AED 533 total
includes taxes & fees
12 Jul - 13 Jul
NYAH Key West - Adults Only

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,006 reviews)
"Loved the location, breakfast and clean room. Staff, Drew, very friendly and helpful. Will definitely stay here again."
United States
Richard
The price is AED 392
AED 441 total
includes taxes & fees
13 Jul - 14 Jul
L'Habitation Guest House

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,007 reviews)
"Great boutique hotel in the perfect location !! "
United States
Michael
The price is AED 704
AED 792 total
includes taxes & fees
15 Jul - 16 Jul
Orchid Key Inn - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

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