A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Adults Only Resorts & Hotels

Our top choices for Florida Keys adults-only hotels

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,008 reviews)
"The room was amazing with a great kitchen, and very clean. The staff was very professional and friendly and the breakfast delicious."
United States
Alina
The price is AED 585
AED 1,123 total
includes taxes & fees
27 Jul - 28 Jul
Southernmost House - Adult Exclusive

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,053 reviews)
"The hotel has a perfect location. We enjoyed the breakfast. It was clean and the staff was amazing."
United States
david
The price is AED 357
AED 481 total
includes taxes & fees
20 Jul - 21 Jul
Duval House

The National Hotel Miami Beach

The National Hotel Miami Beach
4.5 star property
South Beach
9.0 out of 10, Wonderful, (1,798 reviews)
"Great place to stay"
United States
kelsey
The price is AED 493
AED 792 total
includes taxes & fees
3 Aug - 4 Aug
The National Hotel Miami Beach

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (448 reviews)
The price is AED 429
AED 530 total
includes taxes & fees
20 Jul - 21 Jul
Douglas House - Adults Only

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,005 reviews)
"We loved our one night stay here! Everything was very clean and the staff was very helpful in letting us do self check-in since we arrived after 5:30. The breakfast was perfect and I enjoyed the views in the courtyard."
United States
Elizabeth
The price is AED 442
AED 589 total
includes taxes & fees
15 Jul - 16 Jul
The Grand Guesthouse

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,007 reviews)
"Loved the location, breakfast and clean room. Staff, Drew, very friendly and helpful. Will definitely stay here again."
United States
Richard
The price is AED 428
AED 482 total
includes taxes & fees
22 Jul - 23 Jul
L'Habitation Guest House

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
8.2 out of 10, Very Good, (1,013 reviews)
"Great spot, would stay again"
United States
Ben
The price is AED 261
AED 459 total
includes taxes & fees
15 Jul - 16 Jul
NYAH Key West - Adults Only

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,168 reviews)
"Great stay highly recommended"
United States
Lindsay
The price is AED 437
AED 614 total
includes taxes & fees
15 Jul - 16 Jul
Heron House - Adult Only

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very Good, (1,415 reviews)
"Wonderful place"
United States
Clarice
The price is AED 400
AED 616 total
includes taxes & fees
15 Jul - 16 Jul
The Southernmost Inn - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

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