Find Adults Only Resorts & Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Adults Only Resorts & Hotels

This weekend
Next weekend

Our top choices for Florida Keys adults-only hotels

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,001 reviews)
"Fresh continental breakfast, clean room, close to everything."
United States
BOBBY J.
The price is AED 702
AED 1,255 total
includes taxes & fees
21 Jun - 22 Jun
Southernmost House - Adult Exclusive

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,035 reviews)
"Great location and staff"
United States
gerald
The price is AED 511
AED 653 total
includes taxes & fees
3 Jun - 4 Jun
Duval House

Heron House Court - Adult Only

Heron House Court - Adult Only
3.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,003 reviews)
"Property was very pleasant. Staff friendly and helpful. Nice location to wharf, restaurants, and generally all around relaxing. I would definitely stay here again. "
United States
Dawn
The price is AED 407
AED 579 total
includes taxes & fees
3 Jun - 4 Jun
Heron House Court - Adult Only

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (986 reviews)
"The location and customer service were excellent. We loved our stay!"
United States
Megan
The price is AED 460
AED 517 total
includes taxes & fees
2 Jun - 3 Jun
L'Habitation Guest House

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very Good, (1,373 reviews)
"Great location, nice breakfast and happy hour pool was great"
United States
Patrick
The price is AED 445
AED 666 total
includes taxes & fees
10 Jun - 11 Jun
The Southernmost Inn - Adults Only

Tropical Inn

Tropical Inn
3.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (406 reviews)
"Very friendly staff and a prime location."
United States
Akhenaton
The price is AED 620
AED 790 total
includes taxes & fees
7 Jun - 8 Jun
Tropical Inn

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (403 reviews)
"Great stay"
United States
Matthew
The price is AED 544
AED 673 total
includes taxes & fees
4 Jun - 5 Jun
Douglas House - Adults Only

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (323 reviews)
"Love this spot"
United States
Lorraine
The price is AED 625
AED 806 total
includes taxes & fees
3 Jun - 4 Jun
Kona Kai Resort and Gallery - Adults Only

Bahia Bay Resort

Bahia Bay Resort
2.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (175 reviews)
"Amazing stay! Im so happy we found this cute romantic little spot"
United States
Laura
The price is AED 599
AED 673 total
includes taxes & fees
12 Jun - 13 Jun
Bahia Bay Resort

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,153 reviews)
"Fantastic place, clean and great location."
United States
James
The price is AED 436
AED 613 total
includes taxes & fees
3 Jun - 4 Jun
Heron House - Adult Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews

Explore a world of travel with Expedia