A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Luxury Hotels

Tonight
11 Sep - 12 Sep
Tomorrow
12 Sep - 13 Sep
This weekend
11 Sep - 13 Sep
Next weekend
18 Sep - 20 Sep

Our top choices for Florida Keys luxury hotels

1. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,488
AED 1,906 total
includes taxes & fees
14 Sep - 15 Sep
The Islands of Islamorada

2. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
  • Indulge in oceanfront splendor at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.
AED 1,392
AED 1,793 total
includes taxes & fees
13 Sep - 14 Sep
Villas At Hawks Cay Resort

3. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
AED 809
AED 1,195 total
includes taxes & fees
28 Sep - 29 Sep
Ocean Key Resort - A Noble House Resort

4. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
AED 951
AED 1,215 total
includes taxes & fees
14 Sep - 15 Sep
Opal Key Resort & Marina, Key West

5. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
AED 883
AED 1,249 total
includes taxes & fees
23 Sep - 24 Sep
Pier House Resort & Spa

6. Santa Maria Suites

Santa Maria Suites
Old Town Key West
  • Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
AED 1,025
AED 1,401 total
includes taxes & fees
13 Sep - 14 Sep
Santa Maria Suites

7. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 937
AED 1,256 total
includes taxes & fees
27 Sep - 28 Sep
Playa Largo Resort & Spa, Autograph Collection

8. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
Old Town Key West
  • Beachfront luxury graces historic Key West resort with private shore access and spa treatments.
AED 834
AED 1,186 total
includes taxes & fees
22 Sep - 23 Sep
Casa Marina Key West, Curio Collection by Hilton

9. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
13 Sep - 14 Sep
Reefhouse Resort & Marina

10. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
AED 731
AED 1,078 total
includes taxes & fees
28 Sep - 29 Sep
Hyatt Centric Key West Resort and Spa
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Top Florida Keys Hotel Reviews

Parmer's Resort

Parmer's Resort

10/10 Excellent
"Excellent resort, clean. Beautiful views, very friendly staff ♥️"
Mireya 1-night trip
Posted 2 hours ago
Parmer's Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Super good resorts"
Danilo 2-night trip
Posted 14 hours ago
Playa Largo Resort & Spa, Autograph Collection
Lime Tree Bay Resort

Lime Tree Bay Resort

10/10 Excellent
"Overall great experience. Will book again in the future"
Nicholas 3-night trip
Posted 1 day ago
Lime Tree Bay Resort
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"This is my new go-to place to stay in Key Largo! It's clean, quaint & a good location. The view at the dock at Sunset was stunning. We had two queens & a bathroom. Our room was right behind the check in building so it was convenient to us. There also seems to be a table & chairs outside each room, I didn't know that when I booked but I was able to have my morning tea outside. Another nice feature was the in-room fridge (which was super cold), the coffee maker & the microwave. This microwave was nice! It had a USB & 3-prong plug on the front of it & when it stops running it's locked & you have to push the unlock button. If you are traveling with kids, this is a wonderful safety feature! We walked down to the docks twice on our overnight stay. There are chairs on the beach & on the dock. There were plenty of local places to eat, but I recommend C&Cs Wood Fired Pizza for their happy hour from 4-6 pm. A pizza (6 slices) & a pitcher for $10! At the Cottages, the staff were super nice. Irina & the other lady at check in were so helpful. I even asked a grounds person a question & he was helpful too. I don't care about super fancy. I care about CLEAN, a great view & beautiful surrounding. It's all of this & more!"
Stacy 1-night trip
Posted 2 days ago
The Pelican Key Largo Cottages
Islander Resort

Islander Resort

8/10 Good
"Good location. nice clean rooms. bed was very firm. pool tends to get very warm."
Martin 9-night trip
Posted 2 days ago
Islander Resort
Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"I like Everything!"
Ana 1-night trip
Posted 2 days ago
Amara Cay Resort