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Pick from 120 Florida Keys Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.
Little Palm Island Resort & Spa - A Noble House Resort
Little Palm Island Resort & Spa - A Noble House Resort
9.8 out of 10, Exceptional, (42)
H2O Suites - Adults Only
H2O Suites - Adults Only
9.8 out of 10, Exceptional, (481)
The price is AED 1,686
AED 2,024 total
includes taxes & fees
27 May - 28 May
Santa Maria Suites
Santa Maria Suites
9.6 out of 10, Exceptional, (1002)
The price is AED 1,686
AED 2,024 total
includes taxes & fees
17 Jun - 18 Jun
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
9.2 out of 10, Wonderful, (1001)
The price is AED 1,833
AED 2,134 total
includes taxes & fees
27 May - 28 May
Oceans Edge Key West Resort, Hotel & Marina
Oceans Edge Key West Resort, Hotel & Marina
9.0 out of 10, Wonderful, (1515)
The price is AED 644
AED 938 total
includes taxes & fees
27 May - 28 May
Cheeca Lodge & Spa
Cheeca Lodge & Spa
9.0 out of 10, Wonderful, (1006)
The price is AED 1,172
AED 1,537 total
includes taxes & fees
27 May - 28 May
Playa Largo Resort & Spa, Autograph Collection
Playa Largo Resort & Spa, Autograph Collection
9.0 out of 10, Wonderful, (1001)
The price is AED 1,319
AED 1,635 total
includes taxes & fees
10 Jun - 11 Jun
The Marker Key West Harbor Resort
The Marker Key West Harbor Resort
8.8 out of 10, Excellent, (1005)
The price is AED 955
AED 1,271 total
includes taxes & fees
27 May - 28 May
Parmer's Resort
Parmer's Resort
8.8 out of 10, Excellent, (1001)
The price is AED 585
AED 762 total
includes taxes & fees
30 May - 31 May
Southwinds Motel
Southwinds Motel
8.8 out of 10, Excellent, (1007)
The price is AED 709
AED 864 total
includes taxes & fees
28 May - 29 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Florida Keys hotelsExpedia verified reviews
5/5 Excellent
"I had a short and sweet stay."
A verified traveler stayed at Kingsail Resort
Posted 2 days ago
Top neighborhoods for Luxury Hotels
More Hotel Options in Florida Keys
- Adventure Hotels (267)
- All-inclusive Hotel (2)
- Beach Hotels (236)
- Boutique Hotels (34)
- Business Hotels (87)
- Casinos (1)
- Cheap Hotels (92)
- Family Hotels (208)
- Golf Hotels (121)
- Green Hotels (8)
- Historic Hotels (123)
- Hotel Wedding Venues (98)
- Hotel with a Concierge (130)
- Hotels with Bars (164)
- Hotels with Early Check-in (7)
- Hotels with Free Parking (187)
- Hotels with Hot Tubs (113)
- Hotels with Waterslides (2)
- Hotels with WiFi (221)
- Hotels with a Pool (246)
- Hotels with smoking rooms (55)
- Pet-friendly Hotels (73)
- Resorts & Hotels with Spas (99)
- Romantic Hotels (169)
- Shopping Hotels (157)
- Ski Hotels (12)
More Accommodation Types in Florida Keys
- Vacation Homes in United States of America (385,328)
- Condo Rentals in United States of America (186,044)
- Apartments in United States of America (107,636)
- Cabin Rentals in United States of America (60,214)
- Cottages in United States of America (45,387)
- Villas in United States of America (22,137)
- Motels in United States of America (10,089)
- Resorts in United States of America (9,221)
- Guest Houses in United States of America (4,948)
- Aparthotels in United States of America (4,661)
- B&B in United States of America (4,412)
- Chalets in United States of America (3,113)
- Farmstay in United States of America (2,810)
- Lodges in United States of America (2,170)
- RV Parks in United States of America (1,990)
- Houseboats in United States of America (551)
- Inns in United States of America (459)
- Town Houses in United States of America (406)
- Hostels in United States of America (320)
- Condo Resorts in United States of America (162)
- Castles in United States of America (109)
- Holiday Park Resorts in United States of America (90)
- Ranches in United States of America (69)
- Residences in United States of America (66)
- Safari Tentalow in United States of America (20)
- Country Houses in United States of America (17)
- Treehouses in United States of America (13)
- Capsule Hotels in United States of America (4)
- Riads in United States of America (4)
- Pensions in United States of America (1)
Hotels near popular Florida Keys Attractions
- Hotels near Duval Street
- Hotels near Mallory Square
- Hotels near Smathers Beach
- Hotels near John Pennekamp Coral Reef State Park
- Hotels near Sombrero Beach
- Hotels near Southernmost Point
- Hotels near Ernest Hemingway Home and Museum
- Hotels near Fort Zachary Taylor Historic State Park
- Hotels near South Beach
- Hotels near Jimmy Johnson's Big Chill
Florida Keys Hotels by Star Rating
Explore more hotels
- Playa Largo Resort & Spa, Autograph Collection
- Reefhouse Resort & Marina
- Fairfield Inn & Suites by Marriott Marathon Florida Keys
- Amara Cay Resort
- Rock Reef Resort
- Aqua Lodge Rentals At Coconut Cay
- Kingsail Resort
- Waterside Suites & Marina
- Holiday Inn Key Largo, an IHG Hotel
- Islander Resort
- Banana Bay Resort & Marina
- Courtyard by Marriott Faro Blanco Resort
- La Siesta Resort & Villas
- Key Largo Inn
- The Pelican Key Largo Cottages
- Hadley Resort and Marina
- Creekside Inn Islamorada
- Tranquility Bay Beachfront Hotel and Resort
- Rainbow Bend Resort
- Sugarloaf Key Hotel at KOA Resort
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