Find Resorts & Hotels with Spas in Florida Keys
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Pick from 99 Florida Keys Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.
Almond Tree Inn Hotel - Adults Only
Almond Tree Inn Hotel - Adults Only
10.0 out of 10, Exceptional, (1001)
The price is AED 1,620
AED 1,823 total
includes taxes & fees
24 Jun - 25 Jun
Ocean Key Resort - A Noble House Resort
Ocean Key Resort - A Noble House Resort
9.2 out of 10, Wonderful, (1005)
The price is AED 1,355
AED 1,756 total
includes taxes & fees
16 Jun - 17 Jun
Paradise Inn Key West - Adults Only
Paradise Inn Key West - Adults Only
9.2 out of 10, Wonderful, (1000)
The price is AED 547
AED 769 total
includes taxes & fees
28 May - 29 May
The Inn on Fleming
The Inn on Fleming
9.2 out of 10, Wonderful, (569)
The price is AED 878
AED 988 total
includes taxes & fees
27 May - 28 May
Cheeca Lodge & Spa
Cheeca Lodge & Spa
9.0 out of 10, Wonderful, (1006)
The price is AED 1,098
AED 1,483 total
includes taxes & fees
10 Jun - 11 Jun
Hyatt Centric Key West Resort and Spa
Hyatt Centric Key West Resort and Spa
9.0 out of 10, Wonderful, (1003)
The price is AED 1,424
AED 1,800 total
includes taxes & fees
18 Jun - 19 Jun
Seascape Tropical Inn - Adult Exclusive
Seascape Tropical Inn - Adult Exclusive
9.0 out of 10, Wonderful, (365)
The price is AED 808
AED 1,054 total
includes taxes & fees
27 May - 28 May
Heron House Court - Adult Only
Heron House Court - Adult Only
9.0 out of 10, Wonderful, (1005)
The price is AED 526
AED 686 total
includes taxes & fees
27 May - 28 May
Reefhouse Resort & Marina
Reefhouse Resort & Marina
9.0 out of 10, Wonderful, (1181)
The price is AED 902
AED 1,162 total
includes taxes & fees
6 Jun - 7 Jun
Pier House Resort & Spa
Pier House Resort & Spa
8.8 out of 10, Excellent, (1002)
The price is AED 1,833
AED 2,228 total
includes taxes & fees
30 May - 31 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Florida Keys hotelsExpedia verified reviews
5/5 Excellent
R&R
"Didn’t plan enough time here, but it was a very nice place to relax and recharge. "
A verified traveler stayed at Reefhouse Resort & Marina
Posted 2 days ago
Top neighborhoods for Resorts & Hotels with Spas
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More Hotel Options in Florida Keys
- Adventure Hotels (267)
- All-inclusive Hotel (2)
- Beach Hotels (236)
- Boutique Hotels (34)
- Business Hotels (87)
- Casinos (1)
- Cheap Hotels (92)
- Family Hotels (208)
- Golf Hotels (121)
- Green Hotels (8)
- Historic Hotels (123)
- Hotel Wedding Venues (98)
- Hotel with a Concierge (130)
- Hotels with Bars (164)
- Hotels with Early Check-in (7)
- Hotels with Free Parking (187)
- Hotels with Hot Tubs (113)
- Hotels with Waterslides (2)
- Hotels with WiFi (221)
- Hotels with a Pool (246)
- Hotels with smoking rooms (55)
- Luxury Hotels (120)
- Pet-friendly Hotels (73)
- Romantic Hotels (169)
- Shopping Hotels (157)
- Ski Hotels (12)
More Accommodation Types in Florida Keys
- Vacation Homes in United States of America (385,328)
- Condo Rentals in United States of America (186,044)
- Apartments in United States of America (107,636)
- Cabin Rentals in United States of America (60,214)
- Cottages in United States of America (45,387)
- Villas in United States of America (22,137)
- Motels in United States of America (10,089)
- Resorts in United States of America (9,221)
- Guest Houses in United States of America (4,948)
- Aparthotels in United States of America (4,661)
- B&B in United States of America (4,412)
- Chalets in United States of America (3,113)
- Farmstay in United States of America (2,810)
- Lodges in United States of America (2,170)
- RV Parks in United States of America (1,990)
- Houseboats in United States of America (551)
- Inns in United States of America (459)
- Town Houses in United States of America (406)
- Hostels in United States of America (320)
- Condo Resorts in United States of America (162)
- Castles in United States of America (109)
- Holiday Park Resorts in United States of America (90)
- Ranches in United States of America (69)
- Residences in United States of America (66)
- Safari Tentalow in United States of America (20)
- Country Houses in United States of America (17)
- Treehouses in United States of America (13)
- Capsule Hotels in United States of America (4)
- Riads in United States of America (4)
- Pensions in United States of America (1)
Hotels near popular Florida Keys Attractions
- Hotels near Duval Street
- Hotels near Mallory Square
- Hotels near Smathers Beach
- Hotels near John Pennekamp Coral Reef State Park
- Hotels near Sombrero Beach
- Hotels near Southernmost Point
- Hotels near Ernest Hemingway Home and Museum
- Hotels near Fort Zachary Taylor Historic State Park
- Hotels near South Beach
- Hotels near Jimmy Johnson's Big Chill
Florida Keys Hotels by Star Rating
Explore more hotels
- Playa Largo Resort & Spa, Autograph Collection
- Reefhouse Resort & Marina
- Fairfield Inn & Suites by Marriott Marathon Florida Keys
- Amara Cay Resort
- Rock Reef Resort
- Aqua Lodge Rentals At Coconut Cay
- Kingsail Resort
- Waterside Suites & Marina
- Holiday Inn Key Largo, an IHG Hotel
- Islander Resort
- Banana Bay Resort & Marina
- Courtyard by Marriott Faro Blanco Resort
- La Siesta Resort & Villas
- Key Largo Inn
- The Pelican Key Largo Cottages
- Hadley Resort and Marina
- Creekside Inn Islamorada
- Tranquility Bay Beachfront Hotel and Resort
- Rainbow Bend Resort
- Sugarloaf Key Hotel at KOA Resort
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