Find Resorts & Hotels with Spas in Florida Keys, FL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Our top choices for Florida Keys hotels with a spa

1. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,299 reviews)
  • cleanliness
    Restore serenity at this beachfront hotel with 5 tranquil spa treatment rooms and multiple outdoor pools overlooking stunning ocean views.
The price is AED 824
AED 1,149 total
includes taxes & fees
15 Nov - 16 Nov
Isla Bella Beach Resort & Spa

2. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,570 reviews)
  • cleanliness
    Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
The price is AED 804
AED 1,052 total
includes taxes & fees
29 Nov - 30 Nov
Reefhouse Resort & Marina

3. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.6 out of 10, Excellent, (1,129 reviews)
  • cleanliness
    Rejuvenate at this waterfront resort's luxurious Ocean Spa with specialized massages in serene rooms.
The price is AED 509
AED 711 total
includes taxes & fees
17 Nov - 18 Nov
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

4. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1,069 reviews)
  • cleanliness
    Luxurious beachfront spa retreat offers deep-tissue massages and serene outdoor treatments in Key West.
The price is AED 805
AED 1,153 total
includes taxes & fees
30 Nov - 1 Dec
The Reach Key West, Curio Collection by Hilton

5. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Waterfront resort spa with exotic massage options and ocean views offers full-service relaxation by the Key West sunset.
The price is AED 933
AED 1,348 total
includes taxes & fees
29 Nov - 30 Nov
Ocean Key Resort - A Noble House Resort

6. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Luxurious oceanfront escape with 3 spa treatment rooms offers deep-tissue massages, facials, and holistic therapies for pure rejuvenation.
The price is AED 937
AED 1,322 total
includes taxes & fees
1 Dec - 2 Dec
Hyatt Centric Key West Resort and Spa

7. Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,516 reviews)
  • cleanliness
    Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
The price is AED 666
AED 1,018 total
includes taxes & fees
15 Nov - 16 Nov
Cheeca Lodge & Spa

8. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
The price is AED 966
AED 1,289 total
includes taxes & fees
29 Nov - 30 Nov
Playa Largo Resort & Spa, Autograph Collection

9. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
5.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,220 reviews)
  • cleanliness
    Indulge in oceanfront spa retreats with sunset views at this tropical Key West haven just steps from Duval Street.
The price is AED 951
AED 1,215 total
includes taxes & fees
29 Nov - 30 Nov
Opal Key Resort & Marina, Key West

10. Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,391 reviews)
  • cleanliness
    Waterfront spa resort invites relaxation with private beach, outdoor pool, and rejuvenating treatments in Key West's central locale.
The price is AED 1,246
AED 1,658 total
includes taxes & fees
28 Nov - 29 Nov
Pier House Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Florida Keys

Top Florida Keys Hotel Reviews