East Main Street, CO

Grand Junction

A tall, narrow rock formation in a desert canyon with layered rock walls and sparse vegetation.


East Main Street Hotel Deals

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.

Grand Junction CO
Fully refundable
The price is AED 514 per night from Dec 7 to Dec 8
AED 514
AED 1,049 total
7 Dec - 8 Dec
includes taxes & fees
Stay at this vacation home in Grand Junction. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Museum of the West and Western Colorado ...
10/10 Exceptional! (44 reviews)
"Very comfortable and well appointed home. Great communication from host"

Reviewed on 27 October 2026

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
Grand Vista Hotel

Grand Vista Hotel

3.5 out of 5
2790 Crossroads Blvd Grand Junction CO
The price is AED 228 per night from Nov 15 to Nov 16
AED 228
AED 262 total
15 Nov - 16 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
Grand Vista Hotel
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

2 out of 5
728 Horizon Drive Grand Junction CO
The price is AED 225 per night from Nov 18 to Nov 19
AED 225
AED 258 total
18 Nov - 19 Nov
includes taxes & fees
Stay at this hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Super 8 by Wyndham Grand Junction Colorado
Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction

2.5 out of 5
752 Horizon Dr Grand Junction CO
The price is AED 231 per night from Nov 18 to Nov 19
AED 231
AED 265 total
18 Nov - 19 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Ramada by Wyndham Grand Junction
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

3 out of 5
733 Horizon Dr Grand Junction CO
The price is AED 293 per night from Nov 29 to Nov 30
AED 293
AED 336 total
29 Nov - 30 Nov
includes taxes & fees
Book a stay at this golf hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Quality Inn Grand Junction near University
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

3 out of 5
2761 Crossroads Blvd Grand Junction CO
The price is AED 304 per night from Dec 6 to Dec 7
AED 304
AED 348 total
6 Dec - 7 Dec
includes taxes & fees
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (2,840 reviews)
"The clean room, pleasant and helpful staff and convenient parking make this place perfect. This is our second time in three years and both times have been excellent. I will continue to stay here as it is a pleasant experience all around, with or without our dogs."

Reviewed on 12 November 2026

La Quinta Inn & Suites by Wyndham Grand Junction
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East Main Street

Find the best East Main Street areas and neighborhoods for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Western Colorado Center for the Arts.

Pear Park

If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Horizon Drive District

While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Grand Junction Motor Speedway and Canyon View Park.



East Main Street, CO

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