East Main Street, CO
Grand Junction
Visit East Main Street
Popular places to visit
Colorado Mesa University
Enjoy the collegiate vibe at Colorado Mesa University during your stay in Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its lively bars.
Canyon View Park
Explore the lovely green spaces of Canyon View Park and enjoy the biking trails in Grand Junction. Check out the notable monuments and top-notch restaurants in this family-friendly area.
St Mary's Medical Center
Though St Mary's Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Grand Junction while you are here.
Two Rivers Convention Center
Learn about the events happening at Two Rivers Convention Center during your trip to Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its lively bars.
Redlands Mesa Golf Club
Enjoy a round of golf in Grand Junction at Redlands Mesa Golf Club. Check out the notable monuments and lively bars in this family-friendly area.
Bananas Fun Park
Enjoy a fun-filled day at Bananas Fun Park during your trip to Grand Junction. Check out the notable monuments and top-notch restaurants in this family-friendly area.
East Main Street Hotel Deals
Grand Junction Vacation Rental w/ Fire Pit!
Beautiful home! Super clean, spacious, wonderful place to stay. My family enjoyed it so much they wany to go back. Fit our needs perfectly.
Reviewed on 22 December 2025
Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
He was extremely easy to work with and very communicative. Lovely home, easy walk to downtown
Reviewed on 16 December 2025
Launch your Colorado adventures – Historic Downtown convenience
Our host Adam was great, even letting us check in a few hours early. Very responsive and welcoming. The home is well furnished and comfortable. Excellent beds and dining area. For me the kitchen was outstanding! We have to eat a specific diet and the kitchen can make or break a vacation. Well stocked ...
Reviewed on 1 December 2025
Grand Vista Hotel
Nice staff , clean room, best deal
Reviewed on 14 January 2026
La Quinta Inn & Suites by Wyndham Grand Junction
Room was immaculate. We did not get the king room reserved on Hotels.com sadly and it really did ruin the mood for my anniversary night as planned but was not the hotels fault.
Reviewed on 12 January 2026
Clarion Inn Grand Junction
Good job
Reviewed on 12 January 2026
Check East Main Street hotel availability
Other neighborhoods around East Main Street
Lincoln Park Historic District
While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Western Colorado Center for the Arts.
Washington Park
While Washington Park isn't home to many top sights, Western Colorado Center for the Arts and Western Colorado Botanical Gardens are some notable places to visit nearby.
7th Street Historic District
When in 7th Street Historic District, you can plan a visit to Western Colorado Center for the Arts and Western Colorado Botanical Gardens, some noteworthy sights in the nearby area.
Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.
Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.
Grandview
While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Center for the Arts and Western Colorado Botanical Gardens.
East Main Street, CO
- Places of interest
- East Main Street Hotels by Star Rating
- Hotels in top Grand Junction neighborhoods
- East Main Street Hotels by Brand
- Colorado River
- Colorado Mesa University
- Colorado National Monument
- Canyon View Park
- Two Rivers Convention Center
- Redlands Mesa Golf Club
- Bananas Fun Park
- Mesa County Fairgrounds
- Western Colorado Botanical Gardens
- Gunnison River
- High Country Orchards
- Grand Mesa National Forest
- Grand Junction Motor Speedway
- Connected Lakes
- Colorado Welcome Center
- Western Colorado Center for the Arts
- James M. Robb – Colorado River State Park
- Devils Canyon Science and Learning Center
- Unaweep Canyon
- Western Slope Vietnam War Memorial
- Dinosaur Journey
