Find Luxury Hotels in Greenville, SC

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Check availability on Greenville Luxury Hotels

Pick from 21 Greenville Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Greenville?

Use Expedia and let us help you arrange a flight to Greenville-Spartanburg Intl. Airport (GSP) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Greenville offers. While you’re visiting, you might want to think about enjoying the entertainment and live music, which Greenville is known for.

How many luxury hotels will I be able to find in Greenville?

Lie in the lap of luxury during your getaway to Greenville in one of Expedia’s 16 luxury hotels.

When can I expect good weather in Greenville?

Planning for the weather is a good way to make your trip to Greenville relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Greenville is 55 inches.

What's there to see and do in Greenville?

Enjoy Greenville with a stop at The Peace Center, The Children’s Museum of the Upstate, and Falls Park on the Reedy. If you have extra time while you’re in the area, you might want to see Bon Secours Wellness Arena and Greenville Zoo.

How can I get around Greenville?

It’s easier to get around town in style when you know your options. To venture out into the surrounding area, ride aboard one of the trains from Greenville Station.