A long bridge spanning a river, surrounded by lush greenery and fields.

Find Resorts & Hotels with Spas in Greenville, MS

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Check availability on Greenville Resorts & Hotels with Spas

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Greenville hotels with a spa

A salon setting with two people seated, a table with various skincare products, a vase with flowers, and neatly rolled towels in the background.

1. Harlow's Casino Resort & Spa

Harlow's Casino Resort & Spa
3.5 star property
Greenville
8.0 out of 10, Very good, (1,000 reviews)
  • cleanliness
    Relax in riverside luxury with spa treatments featuring hot stone massages, aromatherapy, and deep-tissue therapies in spacious suites.
The price is AED 324
AED 357 total
includes taxes & fees
3 Nov - 4 Nov
Harlow's Casino Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Greenville

Pool
Hot tub

Top Greenville Hotel Reviews

Harlow's Casino Resort & Spa

Harlow's Casino Resort & Spa

8/10 Good
"It was good. I enjoyed the stay."
Vernon 1-night trip
Posted 10 days ago
Harlow's Casino Resort & Spa

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Forget the stress of everyday life and book yourself a lush spa hotel. Check out the live music scene and restaurants in Greenville—your day trip starts here. Enjoy the entertainment choices and riverfront during your vacation. Spa hotels are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Harlow's Casino Resort & Spa is a top spa hotel featuring 3 restaurants, 3 bars, a casino, and a 24-hour fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa.
How many spa hotels are there in Greenville?
Among Expedia's 18 accommodation options in Greenville, there is 1 spa hotel.
What's there to see and do in Greenville?
Take in some sights and attractions while you're in Greenville by visiting Trop Casino Greenville, Greenville Country Club, and Harlow's Casino Resort & Spa. If you have a bit of extra time while you're in the area, you might want to check out Mississippi River and 1927 Flood Museum.
What is a Greenville spa hotel?
Spa hotels in Greenville have on-site spas and offer services such as facials and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.