A church with a steeple and a large tree in front.

Find Resorts & Hotels with Spas in Greenville, AL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Greenville Resorts & Hotels with Spas

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Greenville hotels with a spa

Room

1. Quality Inn & Suites Greenville I-65

Quality Inn & Suites Greenville I-65
2.5 star property
Greenville
7.8 out of 10, Good, (127 reviews)
"Friendly staff, perfect place for one night stay on a long road trip. "
United States
Rudy
The price is AED 372
AED 416 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn & Suites Greenville I-65
A hotel room with two beds, a wooden headboard, a nightstand, a lamp, and a painting of a pier on the wall.

2. Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville
2.0 star property
Greenville
7.0 out of 10, Good, (202 reviews)
"Staff were helpful"
United States
Kimberly
The price is AED 281
AED 333 total
includes taxes & fees
2 Nov - 3 Nov
Days Inn by Wyndham Greenville
A Holiday Inn Express & Suites hotel with a prominent entrance, columns, and a well-lit facade.

3. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
Greenville
9.2 out of 10, Wonderful, (731 reviews)
"This was my second time @ this location. The staff is always so friendly and helpful. The rooms are cleans and the breakfast is great."
United States
Ruby
The price is AED 444
AED 496 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Greenville by IHG
A modern building entrance with a wooden ceiling, glass doors, and a brick facade.

4. Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Greenville
8.6 out of 10, Excellent, (402 reviews)
"Clean room, good breakfast"
United States
Scott
The price is AED 378
AED 423 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Greenville
A hotel room with a large bed, a nightstand with a phone, a desk with a chair, and a window with curtains.

5. Comfort Inn Greenville I-65

Comfort Inn Greenville I-65
2.5 star property
Greenville
8.6 out of 10, Excellent, (985 reviews)
"Comfortable bed- quiet environment- friendly helpful staff- nice shower"
United States
JoA
The price is AED 372
AED 416 total
includes taxes & fees
26 Nov - 27 Nov
Comfort Inn Greenville I-65
A hotel lobby with a reception desk, shelves with snacks, a ceiling fan, and a view through the glass doors.

6. Best Western Greenville Inn

Best Western Greenville Inn
2.5 star property
Greenville
8.2 out of 10, Very good, (934 reviews)
"Traveled overnight with family and a pet. Great stay!"
United States
Kerri
The price is AED 314
AED 353 total
includes taxes & fees
1 Dec - 2 Dec
Best Western Greenville Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Greenville

Pool
Breakfast included

Top Greenville Hotel Reviews

Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

10/10 Excellent
"Decent stop"
Vanessa 1-night trip
Posted 2 weeks ago
Days Inn by Wyndham Greenville

Frequently asked questions

Looking for a spa hotel in Greenville?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the entertainment choices and restaurants in Greenville—your day trip starts here. Take part in recreational activities such as golfing during your vacation. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Greenville?
Enjoy all that Greenville has to offer when you visit Greenville Country Club, Cambrian Ridge, and Greenville City Hall. If you have extra time while you're in the area, you might want to see Beeland Park and East Commerce Street Historic District.
What is a Greenville spa hotel?
Spa hotels in Greenville provide lodging and have an on-site spa offering services including massages and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.