The Best Business Hotels in Homosassa, FL from AED 247 in 2026

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Our top choices for Homosassa business-friendly hotels

A bar area with wooden ceiling, bar stools, and a counter with various bottles.

1. Rodeway Inn Homosassa

Homosassa

Tom

AED 247 total

includes taxes & fees

22 Nov - 23 Nov

A bedroom with a four-poster bed, a desk with a chair, a potted plant, and a wall-mounted clock.

2. Luxury Waterfront Villa at the NEW! SaltBreeze

Homosassa

AED 1,852 total

includes taxes & fees

26 Nov - 27 Nov

A spacious living room with leather sofas, a glass coffee table, and ceiling fans.

3. The Chaz Hotel: Captain's Room (Walk to Springs)

Homosassa

AED 683 total

includes taxes & fees

16 Nov - 17 Nov

A spacious living room with a stone fireplace, large windows, and a ceiling fan.

4. Glass River House with pool half mile to boat ramp and kayak launch & rentals

Homosassa

Ben B.

AED 1,438 total

includes taxes & fees

16 Nov - 17 Nov

A spacious living area with hardwood flooring, a leather sofa, a dining table with chairs, a ceiling fan, and a television on a wooden cabinet.

5. The Chaz Hotel: Chaz River Suite

Homosassa

AED 1,050 total

includes taxes & fees

16 Nov - 17 Nov

A hotel entrance with a glass door, a hallway leading to the interior, and a doormat with a motivational message.

6. Hampton Inn Crystal River, FL

Crystal River

Laura

AED 492 total

includes taxes & fees

13 Dec - 14 Dec

A bar area with a wooden counter, seating, ceiling fans, and a view of the water.

7. PaddleTail Waterfront Lodge, Trademark Collection by Wyndham

Crystal River

Cynthia

AED 510 total

includes taxes & fees

29 Nov - 30 Nov

A modern restaurant with high ceilings, blue and grey walls, and a variety of seating options including tables, booths, and chairs.

8. Holiday Inn Express Crystal River by IHG

Crystal River

James

AED 416 total

includes taxes & fees

13 Dec - 14 Dec

A modern living room with a sofa, a small round table, and a staircase leading to another level.

9. Plantation Resort on Crystal River

Crystal River

Darrin

AED 338 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with a large bed, a desk, a chair, a television, a painting of a sunset over water, and a door.

10. Days Inn by Wyndham Crystal River

Crystal River

Alan

AED 315 total

includes taxes & fees

14 Dec - 15 Dec

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Top Homosassa Hotel Reviews

Holiday Inn Express Hotel & Suites Brooksville West by IHG

10/10 Excellent

"Lady at the Front desk wasn’t the nicest person. We had an unexpected problem. My husband had his back go out and we had to stay another night. When I asked if we could get the same rate, she stated that” we booked through a third party and she couldn’t offer us the same rate!” So, I had to book through Hotels.com to save $30 plus on the next night’s stay. She never offered to match or beat the rate I got online! She acted offended that we got a better price online! She should have met or beaten the online price!!"

Microtel Inn & Suites by Wyndham Spring Hill/Weeki Wachee

10/10 Excellent

"Every staff member was very helpful and went out of there way to help me. Building was very clean and the room was spotless. Very well lit up, safe area, I felt ok to “pre-pack” some things and leave them in the car the night before. Also , the cookies were delicious!!"

Holiday Inn Express Crystal River by IHG

10/10 Excellent

"Our stay was wonderful! We both commented that this hotel was one if the best we have stayed at. We travel every month and it was in our top 5 best hotels! The only thing was we left our dirty clothes bag:( Not your fault...that was the only thing that went wrong on our trip! We will be returning in April and we will definitely book at this location!"

Rodeway Inn Homosassa

10/10 Excellent

"The rooms are beautiful and clean. The outside may leave a bit to be desired, but the rooms are great!! I did struggle with the next room. There were several kids, and it was a lot of noise, but the actual property was wonderful, staff was great, rooms were so clean, beds were very comfortable. It is in a convenient location. There is a bar and restaurant I did not try, but it seemed the locals approved. There was no distraction from the bar or restaurant. We were just a few doors down and had no noise issues from that. I highly recommend this hotel, and I am a bit of a snob. I was a little worried because of the price, but my sister and I are GEN-X er's, the real OG's, so I knew we could handle anything, lol. The rooms actually do look like the pictures!!"

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Check availability on Homosassa Business Hotels

Our top choices for Homosassa business-friendly hotels

1. Rodeway Inn Homosassa

2. Luxury Waterfront Villa at the NEW! SaltBreeze

3. The Chaz Hotel: Captain's Room (Walk to Springs)

4. Glass River House with pool half mile to boat ramp and kayak launch & rentals

5. The Chaz Hotel: Chaz River Suite

6. Hampton Inn Crystal River, FL

7. PaddleTail Waterfront Lodge, Trademark Collection by Wyndham

8. Holiday Inn Express Crystal River by IHG

9. Plantation Resort on Crystal River

10. Days Inn by Wyndham Crystal River

Top Homosassa Hotel Reviews

Holiday Inn Express Hotel & Suites Brooksville West by IHG

Microtel Inn & Suites by Wyndham Spring Hill/Weeki Wachee

PaddleTail Waterfront Lodge, Trademark Collection by Wyndham

Holiday Inn Express Crystal River by IHG

Days Inn by Wyndham Brooksville/Dade City

Rodeway Inn Homosassa

Find Business Hotels in Homosassa, FL

Change your mind

Treat yourself

Be picky

Check availability on Homosassa Business Hotels

Our top choices for Homosassa business-friendly hotels

1. Rodeway Inn Homosassa

2. Luxury Waterfront Villa at the NEW! SaltBreeze

3. The Chaz Hotel: Captain's Room (Walk to Springs)

4. Glass River House with pool half mile to boat ramp and kayak launch & rentals

5. The Chaz Hotel: Chaz River Suite

6. Hampton Inn Crystal River, FL

7. PaddleTail Waterfront Lodge, Trademark Collection by Wyndham

8. Holiday Inn Express Crystal River by IHG

9. Plantation Resort on Crystal River

10. Days Inn by Wyndham Crystal River

Top Homosassa Hotel Reviews

Holiday Inn Express Hotel & Suites Brooksville West by IHG