Find hotels in South Main, Houston from AED 266
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Our top choices for South Main hotels
Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,004 reviews)
"Good parking"
joseph
The price is AED 290
AED 339 total
includes taxes & fees
6 Jun - 7 Jun
Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.6 out of 10, Excellent, (1,004 reviews)
"Clean & comfortable, super nice staff, good breakfast options, convenient to MDA."
Cleota
The price is AED 422
AED 494 total
includes taxes & fees
7 Jun - 8 Jun
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.2 out of 10, Good, (1,290 reviews)
"Would stay again!"
Austin
The price is AED 503
AED 589 total
includes taxes & fees
11 Jun - 12 Jun
Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (867 reviews)
"My stay was perfect "
Fredrick
The price is AED 353
AED 413 total
includes taxes & fees
8 Jun - 9 Jun
Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,003 reviews)
"Very clean rooms and excellent staff"
Efrain
The price is AED 277
AED 324 total
includes taxes & fees
9 Jun - 10 Jun
Courtyard by Marriott Houston Intercontinental Airport
Courtyard by Marriott Houston Intercontinental Airport31.8 km from South Main
9.0 out of 10, Wonderful, (1,221 reviews)
"Wonderful place to stay!"
Lisa
The price is AED 511
AED 597 total
includes taxes & fees
6 Jun - 7 Jun
Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
9.4 out of 10, Exceptional, (270 reviews)
"Clean room, and very helpful staff actually enjoyed our stay"
Jessica
The price is AED 364
AED 425 total
includes taxes & fees
7 Jun - 8 Jun
Studio 6 Houston, TX – Pearland/Medical Center
Studio 6 Houston, TX – Pearland/Medical CenterSoutheast Houston, 12.9 km from South Main
9.4 out of 10, Exceptional, (94 reviews)
"The property was very clean and the staff was great. I would stay here again when back in town."
Cruz
The price is AED 228
AED 266 total
includes taxes & fees
8 Jun - 9 Jun
Hotel Royale
Hotel Royale20.9 km from South Main
9.2 out of 10, Wonderful, (41 reviews)
"Room was very clean and convenient for my short stay. Would recommend for business trips. "
Jerome
The price is AED 281
AED 329 total
includes taxes & fees
8 Jun - 9 Jun
Palace Inn Blue 290 W 43rd & Bingle Rd
Palace Inn Blue 290 W 43rd & Bingle Rd19.4 km from South Main
9.0 out of 10, Wonderful, (71 reviews)
"We loved it, very nice employees and very clean."
Jorge
The price is AED 322
AED 377 total
includes taxes & fees
8 Jun - 9 Jun
Crystal Inn Northeast Houston Downtown I-610
Crystal Inn Northeast Houston Downtown I-610Northside, 18.9 km from South Main
8.4 out of 10, Very Good, (209 reviews)
"Great price and nice rooms"
Armando
The price is AED 248
AED 290 total
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Express Hotel & Suites - Houston Space Center by IHG
Holiday Inn Express Hotel & Suites - Houston Space Center by IHG30.8 km from South Main
9.0 out of 10, Wonderful, (1,014 reviews)
"Wonderful enjoyed the stay and breakfast clean rooms"
Albert
The price is AED 323
AED 378 total
includes taxes & fees
6 Jul - 7 Jul
Doubletree by Hilton Houston Hobby Airport
Doubletree by Hilton Houston Hobby AirportSoutheast Houston, 14.5 km from South Main
8.8 out of 10, Excellent, (1,009 reviews)
"This was a great stay. We liked the suite, would have liked a microwave in there."
Sara
The price is AED 373
AED 441 total
includes taxes & fees
5 Jul - 6 Jul
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham18.5 km from South Main
8.8 out of 10, Excellent, (1,201 reviews)
"The room was clean, staff was friendly, breakfast was great, and the area and location was nice and quiet."
Dr. Cherie
The price is AED 309
AED 355 total
includes taxes & fees
7 Jun - 8 Jun
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Hampton Inn & Suites Houston-Bush Intercontinental Aprt31.8 km from South Main
8.8 out of 10, Excellent, (1,910 reviews)
"I would stay here again. Nice?"
Alan
The price is AED 412
AED 485 total
includes taxes & fees
27 Jun - 28 Jun
Palace Inn Blue Edgebrook
Palace Inn Blue Edgebrook16.8 km from South Main
9.4 out of 10, Exceptional, (176 reviews)
"It was very clean"
Jesus
Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownMidtown, 9.1 km from South Main
9.2 out of 10, Wonderful, (159 reviews)
"Great place. The staff is very friendly and the place is clean."
Fernando
The price is AED 321
AED 375 total
includes taxes & fees
8 Jun - 9 Jun
Tru by Hilton Houston Webster NASA
Tru by Hilton Houston Webster NASA30.7 km from South Main
9.0 out of 10, Wonderful, (1,007 reviews)
"Definitely will stay here again. Great location near Great Wolf Lodge."
Deanndra
The price is AED 308
AED 361 total
includes taxes & fees
28 Jun - 29 Jun
SpringHill Suites by Marriott Houston Intercontinental Arprt
SpringHill Suites by Marriott Houston Intercontinental Arprt31.8 km from South Main
9.0 out of 10, Wonderful, (1,803 reviews)
"The staff were super helpful when needed something and the breakfast was a different buffet everyday made the stay even better"
Fawzia
The price is AED 512
AED 599 total
includes taxes & fees
6 Jul - 7 Jul
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
La Quinta Inn & Suites by Wyndham Houston Bush IAH South31.2 km from South Main
8.0 out of 10, Very Good, (2,073 reviews)
"Clean convenient close to airport and food"
Brian
The price is AED 341
AED 398 total
includes taxes & fees
8 Jun - 9 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Main
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Comfort Suites Houston near Medical Center- NRG Stadium | 8.6 Excellent 1,004 reviews | View | ||||||
 Candlewood Suites Houston Medical Center by IHG | 7.4 Good 867 reviews | View | ||||||
 Wyndham Houston near NRG Park/Medical Center | 7.2 Good 1,290 reviews | View | ||||||
 Wingate Houston near NRG Park/Medical Center | 6.6 1,004 reviews | View | ||||||
 Quality Inn & Suites NRG Park - Medical Center | 6.6 1,003 reviews | View |
Where to stay in South Main
Find the best South Main areas and neighborhoods for the activities you enjoy most.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
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