South Central Houston, TX
Houston
Visit South Central Houston
Popular places to visit
Rice University
Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's acclaimed theater scene and lively festivals.
University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the lively festivals and acclaimed theater scene in this vibrant area.
Houston Zoo
Why not visit the native and exotic animals who call Houston Zoo home during your trip to Houston? Experience the area's fascinating museums and acclaimed theater scene.
Houston Natural Science Museum
You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's acclaimed theater scene and lively festivals.
Houston Museum of Fine Arts
You can spend time exploring the galleries in Houston Museum of Fine Arts during your trip to Houston. Experience the area's lively festivals and great live music.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's lively festivals and acclaimed art scene.
South Central Houston Hotel Deals
Hilton Houston Plaza/Medical Center
Clean room
Reviewed on 12 January 2026
Hotel Zaza Houston Museum District
Everything was nice except the pillows, if you can even call them that. Pillows should be trashed.
Reviewed on 2 January 2026
The Westin Houston Medical Center/Museum District
Great hotel - feels like a moment of vacation while going to the medical center
Reviewed on 10 January 2026
Downtowner Inns - Houston Downtown
Clean room, staff was friendly and accommodating.
Reviewed on 12 January 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Very nice and clean and comfortable
Reviewed on 11 January 2026
InterContinental Houston by IHG
Bar snacks were delicious and service was very good. The hotel was very comfortable and our room was nice.
Reviewed on 12 January 2026
Other neighborhoods around South Central Houston
Greater Third Ward
While you're in Greater Third Ward, take in top sights like Carl Lewis International Track and Field Complex or Fertitta Center, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.
Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
South Central Houston, TX
- MD Anderson Cancer Center
- Rice University
- University of Houston
- Houston Zoo
- Houston Natural Science Museum
- Texas Children's Hospital
- Houston Methodist Hospital
- Texas Southern University
- Houston Museum of Fine Arts
- Children's Museum of Houston
- Main Street Theater - Rice Village
- Hermann Park
- Memorial Hermann Hospital
- Continental Club
- Harris Health System - Ben Taub General Hospital
- Midtown Arts and Theater Center Houston
- Chi St. Lukes Health Baylor College Of Medicine Medical Center
- Health Museum
- Carl Lewis International Track and Field Complex
- TDECU Stadium
- Ensemble Theatre
- Conrad Hilton Archives
- Houston Fire Museum
- Buffalo Soldiers National Museum
- Holocaust Museum Houston
- Miller Outdoor Theater
