South Main, TX

Houston

Photo by Hazem Abdul

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South Main Hotel Deals

Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
The price is AED 393 per night from May 24 to May 25
AED 393
AED 460 total
24 May - 25 May
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,340 reviews)
"Thanks."

Reviewed on 16 May 2025

Club Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
3.5 out of 5
6633 Travis St, Houston, TX
The price is AED 364 per night from May 25 to May 26
AED 364
AED 430 total
25 May - 26 May
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,338 reviews)
"Close to medical facilities and easy in and out."

Reviewed on 13 May 2025

Hilton Houston Plaza/Medical Center
Holiday Inn Houston Downtown by IHG
Holiday Inn Houston Downtown by IHG
3 out of 5
1616 Main St, Houston, TX
The price is AED 426 per night from Jun 7 to Jun 8
AED 426
AED 563 total
7 Jun - 8 Jun
includes taxes & fees
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,241 reviews)
"Was here for a few days it was cool"

Reviewed on 15 May 2025

Holiday Inn Houston Downtown by IHG
Heritage Place Houston Brookhollow
Heritage Place Houston Brookhollow
3 out of 5
2504 North Loop West, Houston, TX
The price is AED 309 per night from May 19 to May 20
AED 309
AED 364 total
19 May - 20 May
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (149 reviews)
"Staff was great."

Reviewed on 16 May 2025

Heritage Place Houston Brookhollow
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel
4 out of 5
1100 Texas St, Houston, TX
The price is AED 406 per night from May 22 to May 23
AED 406
AED 482 total
22 May - 23 May
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,026 reviews)
"Not in the best neighborhood and getting to the valet parking is next to impossible. Once inside all is good."

Reviewed on 17 May 2025

Magnolia Hotel Houston, A Tribute Portfolio Hotel
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
The price is AED 363 per night from Jun 8 to Jun 9
AED 363
AED 425 total
8 Jun - 9 Jun
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,434 reviews)
"Very nice friendly staff. Great stay"

Reviewed on 14 May 2025

The Whitehall Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around South Main

#race

Astrodome

4/5(276 area reviews)

If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Arena and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.

Astrodome
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Texas Medical Center

4/5(566 area reviews)

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Texas Medical Center
Hermann Park featuring landscape views and a park

Houston Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park featuring landscape views and a park

South Central Houston

4.5/5(74 area reviews)

If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection which includes art and interior views

Montrose

4/5(128 area reviews)

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Montrose
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The Galleria

4.5/5(1,957 area reviews)

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

The Galleria

South Main, TX

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