Top Guest Houses in Iowa in 2026

A city skyline with a river in the foreground, a bridge, and various buildings including a bank.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Top Cities in Iowa

A city skyline at dusk with illuminated buildings and a bridge over a river.

Our top choices for Iowa guest houses

A hotel room with a large bed, a headboard with three pillows, a wall-mounted TV displaying a snowy landscape, and a wooden nightstand with a lamp.

1. The Northwest Inn

Spencer

Michelle

AED 284 total

includes taxes & fees

4 Nov - 5 Nov

A room with wooden walls and ceiling, a large window with a view of a red building, and a ceiling fan.

2. Little River Inn Motel & Guest House

Leon

Troy

AED 361 total

includes taxes & fees

15 Nov - 16 Nov

A building with a porch, outdoor seating, and a flag.

3. Gorgeous loft in the heart of LeClaire, Iowa

Le Claire

Tina K.

AED 1,024 total

includes taxes & fees

17 Nov - 18 Nov

A red barn with a covered porch, white chairs, and a small table.

4. Little Country House a Quiet Countryside Getaway!

Newton

Brook G.

AED 359 total

includes taxes & fees

4 Nov - 5 Nov

A historic building with a sign reading "American House 1854."

5. American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6

McGregor

Brad H.

AED 1,078 total

includes taxes & fees

4 Nov - 5 Nov

A reception area with a stone counter, a computer desk, and a dining area in the background.

6. Quality Inn Creston

Creston

A room with a wooden paneled wall, a large window with a view of the outside, a television mounted on the wall, a grey sofa, a small round table with two stools, and a potted plant.

7. Rustic 1900 building turned cozy studio

Sidney

Monica B.

A modern kitchen with a wooden dining table, white cabinetry, and a built-in oven.

8. Carriage House - Historic Louden Hay Trolley + EV

Fairfield

Stephen W.

AED 685 total

includes taxes & fees

2 Dec - 3 Dec

A brick pathway leading to a house with a front door and a small porch.

9. The Hayloft - Newly Renovated Historic Home + EV

Fairfield

AED 653 total

includes taxes & fees

16 Nov - 17 Nov

10. American House 1854

McGregor

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Iowa Hotel Reviews

Grand Harbor Resort

10/10 Excellent

"Very nice stay great free breakfast,"

Stoney Creek Hotel Des Moines - Johnston

8/10 Good

"We booked a King room and were initially given a double. We spoke with the front desk and it was fixed. Our room had some missing lightbulbs and the bed was softer than we like. The hotel was super cute. We loved the decor. The trash cans were all overflowing at breakfast and no one was emptying them. There were also random empty cups above doorways that other guests left for whatever reason but weren’t cleaned up. Overall, we would still rate our stay a 4.5/5. It was honestly minor things."

Drury Inn & Suites Iowa City Coralville

10/10 Excellent

"This place is awesome. Perfect location if you are attending games at the Mercedes Benz stadium or the State Farm arena. The staff is amazing. I would like to recognize the young lady who checked us in she was awesome. I hate I didn’t get her name!"

Explore a world of travel with Expedia

Des Moines Vacation Rentals

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Top Cities in Iowa

Des Moines

Our top choices for Iowa guest houses

1. The Northwest Inn

2. Little River Inn Motel & Guest House

3. Gorgeous loft in the heart of LeClaire, Iowa

4. Little Country House a Quiet Countryside Getaway!

5. American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6

6. Quality Inn Creston

7. Rustic 1900 building turned cozy studio

8. Carriage House - Historic Louden Hay Trolley + EV

9. The Hayloft - Newly Renovated Historic Home + EV

10. American House 1854

Top Iowa Hotel Reviews

Grand Harbor Resort

Stoney Creek Hotel Des Moines - Johnston

Gateway Hotel and Conference Center at Iowa State University

Hotel Fort Des Moines, Curio Collection by Hilton

Wildwood Lodge

Drury Inn & Suites Iowa City Coralville

Harrah's Council Bluffs Hotel & Casino - A Caesars Rewards Destination

Hotel Julien Dubuque

Des Lux Hotel

Explore a world of travel with Expedia