Irene Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AEDĀ 5,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Irene Vacation Packages

Irene Hotel Deals

Comfort Inn Yankton SD

Comfort Inn Yankton SD

2.5 out of 5
611 W 23rd Street Yankton SD
Fully refundable
The price is AEDĀ 350 per night from Dec 6 to Dec 7
AEDĀ 350
AEDĀ 387 total
6 Dec - 7 Dec
includes taxes & fees
Comfort Inn Yankton SD
Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive Yankton SD
The price is AEDĀ 397 per night from Nov 15 to Nov 16
AEDĀ 397
AEDĀ 419 total
15 Nov - 16 Nov
includes taxes & fees
Lewis and Clark Resort
Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton

3 out of 5
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
The price is AEDĀ 465 per night from Nov 22 to Nov 23
AEDĀ 465
AEDĀ 513 total
22 Nov - 23 Nov
includes taxes & fees
9.4/10 Exceptional! (200 reviews)
"The staff was amazingly nice and helpful!!!! Would have given 10 stars for service if I could."

Reviewed on 29 October 2026

Fairfield Inn & Suites by Marriott Yankton
See all 89 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Irene vacation package cost?
You can snap up a vacation package to this destination on Expedia. However, how much your vacation to Irene costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Irene?
You can typically find lower rates and greater availability in January, February and November. Explore our cheap Irene vacation packages and you could get some excellent off-season deals.
How to find the best Irene package deals?
Bagging a cheap Irene package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can customize your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most economical Irene package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book an Irene vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll typically get a better deal than booking each component individually. And you'll still have the freedom to create a customized Irene vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Irene?
If you've got your Irene travel dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous adventures? Our last-minute deals are ideal for setting off on a whim.
How to plan a trip to Irene?

  1. Choose when to go: Check your calendar and get packing. Your favorite time of year and the activities on offer will also help you decide when to escape to Irene.
  2. Calculate your budget: Make sure you have enough money to cover everything from transportation and food to flights and activities. Your accommodations will likely be the largest expense during your trip to Irene.
  3. Decide how long to go for: Now that you know more about Irene, you can work out the perfect length of your break. Put together a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Irene vacation package.