Find Resorts & Hotels with Spas in Islamorada, FL

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Check prices for these dates

Tonight
7 Nov - 8 Nov
Tomorrow
8 Nov - 9 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Our top choices for Islamorada hotels with a spa

A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.

1. Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,509 reviews)
  • cleanliness
    Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
The price is AED 666
AED 1,018 total
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
The price is AED 966
AED 1,289 total
includes taxes & fees
29 Nov - 30 Nov
Playa Largo Resort & Spa, Autograph Collection
A spacious interior with a high ceiling, large windows, and a central light fixture.

3. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.8 out of 10, Excellent, (1,200 reviews)
The price is AED 967
AED 1,290 total
includes taxes & fees
29 Nov - 30 Nov
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A hotel room with two beds, a large window with a view of a balcony, and a curtain on the window.

4. The Islands of Islamorada

The Islands of Islamorada
5.0 star property
Matecumbe
9.6 out of 10, Exceptional, (83 reviews)
  • cleanliness
    Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
The price is AED 2,437
AED 3,010 total
includes taxes & fees
30 Nov - 1 Dec
The Islands of Islamorada
A tropical resort with a clear pool, palm trees, and lounge chairs.

5. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (368 reviews)
  • cleanliness
    Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
The price is AED 691
AED 881 total
includes taxes & fees
10 Nov - 11 Nov
Kona Kai Resort and Gallery - Adults Only
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.

6. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,565 reviews)
  • cleanliness
    Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
The price is AED 804
AED 1,052 total
includes taxes & fees
29 Nov - 30 Nov
Reefhouse Resort & Marina
A spa room with three reclining chairs, a wall with spherical decorations, and a staircase.

7. Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very good, (1,003 reviews)
  • cleanliness
    Revitalize with luxurious treatments at this waterfront sanctuary featuring 8 spa rooms, sauna, and hot tub escapes.
The price is AED 800
AED 1,236 total
includes taxes & fees
15 Nov - 16 Nov
Hawks Cay Resort
A room with a bed, two chairs, and a view of a lake.

8. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
3.5 star property
Key Largo
9.6 out of 10, Exceptional, (4 reviews)
  • cleanliness
    Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
The price is AED 2,578
AED 2,900 total
includes taxes & fees
8 Nov - 9 Nov
Premium Floating Bungalow by Stay Ombi
A spa room with three lounge chairs, a wall of decorative buttons, and a window with a view.

9. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very good, (233 reviews)
The price is AED 1,686
AED 2,124 total
includes taxes & fees
16 Nov - 17 Nov
Villas At Hawks Cay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Islamorada

Pool
Hot tub

Spa hotels with pools in Islamorada

A bathroom with a large bathtub, a view of the sea, and a pier with boats.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1509)
The price is AED 666
AED 1,018 total
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
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Spa hotels with hot tubs in Islamorada

A bathroom with a large bathtub, a view of the sea, and a pier with boats.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1509)
The price is AED 666
AED 1,018 total
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Islamorada Hotel Reviews

A tropical resort with a clear pool, palm trees, and lounge chairs.
Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor

10/10 Excellent

Best getaway in the Keys. Quiet, good vibes and friendly staff. Highly recommended.
United States
Audrey
Reviewed August 4, 2025
Kona Kai Resort and Gallery - Adults Only

Frequently Asked Questions

Looking for a spa hotel in Islamorada?

Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the sea views in Islamorada. Be sure to enjoy activities like snorkeling and fishing during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your weekend away.

What is the best spa hotel in Islamorada?

Cheeca Lodge & Spa is a top beachfront spa hotel featuring 3 pools, 3 restaurants, a golf course, and a 24-hour fitness center. Treat yourself to a facial, body scrub, or detox wrap at the onsite spa. In-room massages are also available.

How many spa hotels will I find in Islamorada?

Among Expedia's 850 accommodation options in Islamorada, there is 1 spa hotel.

What's there to see and do in Islamorada?

Enjoy Islamorada with a stop at Bud n' Mary's Dive Center, Robbie’s of Islamorada, and Anne's Beach. If you have some spare time during your trip, you might want to check out Fiesta Key and Everglades National Park.

What is a Islamorada spa hotel?

Spa hotels in Islamorada provide lodging and have a full on-site spa offering services such as therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.