Search Vacation Homes in Jefferson

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Jefferson vacation homes

Welcome to the Rusty Rose-Restored Farmhouse feel in the heart of Jefferson, MD

Welcome to the Rusty Rose-Restored Farmhouse feel in the heart of Jefferson, MD
Jefferson
9.8 out of 10, Exceptional, (63 reviews)
"The beds were incredibly comfortable. Great house. Great location. "
United States
Julie B.
The price is AED 331
AED 903 total
includes taxes & fees
27 May - 28 May
Welcome to the Rusty Rose-Restored Farmhouse feel in the heart of Jefferson, MD

RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.

RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.
Downtown Frederick
9.4 out of 10, Exceptional, (126 reviews)
"Great stay, excellent location and host was always readily available. Highly recommended!"
United States
Zayde C.
The price is AED 364
AED 962 total
includes taxes & fees
1 Jun - 2 Jun
RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.

Sharpsburg Retreat--Civil War Home Near Antietam Battlefield, C&O Canal Towpath

Sharpsburg Retreat--Civil War Home Near Antietam Battlefield, C&O Canal Towpath
Sharpsburg
9.6 out of 10, Exceptional, (200 reviews)
"We enjoyed our stay and the location was excellent"
United States
Barbara W.
The price is AED 533
AED 642 total
includes taxes & fees
22 May - 23 May
Sharpsburg Retreat--Civil War Home Near Antietam Battlefield, C&O Canal Towpath

Leesburg Hideaway- King Bed + Private Backyard

Leesburg Hideaway- King Bed + Private Backyard
Leesburg
10.0 out of 10, Exceptional, (34 reviews)
"Adorable, comfy, private & well appointed. Well cleared of snow for our arrival after a difficult snow/ice storm. Comfortable mattress was a bonus. We enjoyed our stay! "
United States
Amy M.
The price is AED 496
AED 1,124 total
includes taxes & fees
25 May - 26 May
Leesburg Hideaway- King Bed + Private Backyard

Charming "Cream of the Crop" Cape ~❤️of Middletown

Charming "Cream of the Crop" Cape ~❤️of Middletown
Middletown
10.0 out of 10, Exceptional, (145 reviews)
"Love the place will book again"
United States
WAYNE M.
The price is AED 331
AED 903 total
includes taxes & fees
28 May - 29 May
Charming "Cream of the Crop" Cape ~❤️of Middletown

"Lovely Tiny House Rental for a Romantic Getaway in Shepherdstown, West Virginia

"Lovely Tiny House Rental for a Romantic Getaway in Shepherdstown, West Virginia
Shepherdstown
The price is AED 387
AED 512 total
includes taxes & fees
26 May - 27 May
"Lovely Tiny House Rental for a Romantic Getaway in Shepherdstown, West Virginia

Luxury Condo In Downtown Frederick

Luxury Condo In Downtown Frederick
Downtown Frederick
9.2 out of 10, Wonderful, (89 reviews)
"Great location and very comfortable. Definitely will consider for future trips to this area."
United States
Jon E.
The price is AED 493
AED 1,165 total
includes taxes & fees
25 May - 26 May
Luxury Condo In Downtown Frederick

Stylish Studio with Kitchenette

Stylish Studio with Kitchenette
Sterling
The price is AED 279
AED 590 total
includes taxes & fees
31 May - 1 Jun
Stylish Studio with Kitchenette

Custom Train-Themed Lodge on 7 Private Acres with Walking Trails

Custom Train-Themed Lodge on 7 Private Acres with Walking Trails
Martinsburg
9.8 out of 10, Exceptional, (23 reviews)
"Host was super nice and location was pretty. "
United States
Kimberly B.
The price is AED 430
AED 1,092 total
includes taxes & fees
22 May - 23 May
Custom Train-Themed Lodge on 7 Private Acres with Walking Trails

4-bedroom house close to Shenandoah River and VA wineries - WiFi, AC, trampoline

4-bedroom house close to Shenandoah River and VA wineries - WiFi, AC, trampoline
Harpers Ferry
9.6 out of 10, Exceptional, (4 reviews)
"House was beautiful and fully equipped for our stay. The host was very communicative and we really enjoyed our time here. If in the area again would definitely stay here. "
United States
Maeve K.
The price is AED 331
AED 1,463 total
includes taxes & fees
25 May - 26 May
4-bedroom house close to Shenandoah River and VA wineries - WiFi, AC, trampoline

The Blue Jay | New House in the Woods

The Blue Jay | New House in the Woods
Harpers Ferry
10.0 out of 10, Exceptional, (1 review)
"Great place. Very well stocked house everything you need Great response from host. Very nice place. Road is a little rough as explained in listing "
United States
Brett D.
The Blue Jay | New House in the Woods

Huckleberry Hills | Hot Tub & Fire Pit & Dogs

Huckleberry Hills | Hot Tub & Fire Pit & Dogs
Harpers Ferry
9.6 out of 10, Exceptional, (10 reviews)
"We had a great stay "
United States
Lauren O.
The price is AED 367
AED 1,492 total
includes taxes & fees
25 May - 26 May
Huckleberry Hills | Hot Tub & Fire Pit & Dogs

Bluemont home just minutes to wineries, breweries, hiking and more!

Bluemont home just minutes to wineries, breweries, hiking and more!
Bluemont
The price is AED 492
AED 1,320 total
includes taxes & fees
2 Jun - 3 Jun
Bluemont home just minutes to wineries, breweries, hiking and more!

New townhouse

New townhouse
Frederick
9.4 out of 10, Exceptional, (10 reviews)
"This property was impeccably clean and so comfortable! The beds were incredibly cozy, and the kitchen was well-stocked. We felt right at home and enjoyed our stay immensely. Beds were comfortable, and kitchen well stocked. The location can't be beat, with so many attractions and wonderful restaurants within a short drive. Tons of nice touches for our arrival; great communication; easy access. We will definitely stay here again!"
United States
Traci U.
The price is AED 555
AED 1,336 total
includes taxes & fees
24 May - 25 May
New townhouse

Mountain Lake Retreat of Harpers Ferry; Hot Tub-Fenced Yard-Firepit-Winery-Beach

Mountain Lake Retreat of Harpers Ferry; Hot Tub-Fenced Yard-Firepit-Winery-Beach
Harpers Ferry
9.6 out of 10, Exceptional, (5 reviews)
The price is AED 356
AED 1,172 total
includes taxes & fees
3 Jun - 4 Jun
Mountain Lake Retreat of Harpers Ferry; Hot Tub-Fenced Yard-Firepit-Winery-Beach

Mountain Chic Retreat-Harpers Ferry, the AT, Wine country w/ Lake Beach passes!

Mountain Chic Retreat-Harpers Ferry, the AT, Wine country w/ Lake Beach passes!
Harpers Ferry
10.0 out of 10, Exceptional, (7 reviews)
"Welcoming host, great place!"
United States
Amanda M.
The price is AED 580
AED 1,476 total
includes taxes & fees
26 May - 27 May
Mountain Chic Retreat-Harpers Ferry, the AT, Wine country w/ Lake Beach passes!

Rural & Historic Detour Escape w/ Horses On-Site!

Rural & Historic Detour Escape w/ Horses On-Site!
Detour
9.4 out of 10, Exceptional, (3 reviews)
"Check-in was super easy. Communication with the owners was quick and easy. There was one hiccup that came up and were very quick to resolve. The house itself is a great historic home. They have done a great job modernizing it. My only feedback would be to have more supplies in the kitchen to accommodate preparing foods like knives, cutting boards, trays, etc. But otherwise, very happy with our stay and the beautiful property, and it being dog friendly!"
United States
Rachel W.
The price is AED 441
AED 1,614 total
includes taxes & fees
26 May - 27 May
Rural & Historic Detour Escape w/ Horses On-Site!

Large Groups, Hot Tub, Near Attractions, Wooded/Country Setting w/Aparment/Annex

Large Groups, Hot Tub, Near Attractions, Wooded/Country Setting w/Aparment/Annex
Harpers Ferry
9.8 out of 10, Exceptional, (109 reviews)
"Laura was extremely helpful as we sorted out what we needed. Amazing location near Harpers Ferry and tons of fun stuff to do right there within shouting distance of the property."
United States
Steve Y.
The price is AED 534
AED 1,952 total
includes taxes & fees
25 May - 26 May
Large Groups, Hot Tub, Near Attractions, Wooded/Country Setting w/Aparment/Annex

Nice and modern decor, 4BR 3BA, remodeled

Nice and modern decor, 4BR 3BA, remodeled
Hagerstown
9.8 out of 10, Exceptional, (28 reviews)
"Amazing house!Spotless and comfortable!Great location "
United States
Joe P.
Nice and modern decor, 4BR 3BA, remodeled

Terra Alta - Incredible River Views and Hot Tub!

Terra Alta - Incredible River Views and Hot Tub!
Charles Town
9.6 out of 10, Exceptional, (70 reviews)
"Nice quiet view, able to sit on deck for hours and talk. Close to restaurants, and stores. Had a great stay."
United States
Paul M.
The price is AED 896
AED 2,237 total
includes taxes & fees
7 Jun - 8 Jun
Terra Alta - Incredible River Views and Hot Tub!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Jefferson Hotel Reviews

Explore a world of travel with Expedia