A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
10 Sep - 11 Sep
Tomorrow
11 Sep - 12 Sep
This weekend
11 Sep - 13 Sep
Next weekend
18 Sep - 20 Sep

Our top choices for Key Largo luxury hotels

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 937
AED 1,256 total
includes taxes & fees
24 Sep - 25 Sep
Playa Largo Resort & Spa, Autograph Collection

2. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
13 Sep - 14 Sep
Reefhouse Resort & Marina

3. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
AED 870
AED 1,182 total
includes taxes & fees
28 Sep - 29 Sep
Baker's Cay Resort Key Largo, Curio Collection by Hilton

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,488
AED 1,906 total
includes taxes & fees
13 Sep - 14 Sep
The Islands of Islamorada

5. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
AED 1,671
AED 2,470 total
includes taxes & fees
14 Sep - 15 Sep
Find Peace - Tiny House in Japanese Garden

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
AED 719
AED 1,057 total
includes taxes & fees
17 Sep - 18 Sep
Islander Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
AED 673
AED 1,026 total
includes taxes & fees
17 Sep - 18 Sep
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 547
AED 884 total
includes taxes & fees
15 Sep - 16 Sep
Cheeca Lodge & Spa

9. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
AED 494
AED 824 total
includes taxes & fees
15 Sep - 16 Sep
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

8/10 Good
"Happens for a little old, but the room was clean nice big kitchen with a stove, dining area or sitting area to eat table to queen beds nice view"
Ann marie 2-night trip
Posted 15 hours ago
Marina Del Mar Resort and Marina
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"This is my new go-to place to stay in Key Largo! It's clean, quaint & a good location. The view at the dock at Sunset was stunning. We had two queens & a bathroom. Our room was right behind the check in building so it was convenient to us. There also seems to be a table & chairs outside each room, I didn't know that when I booked but I was able to have my morning tea outside. Another nice feature was the in-room fridge (which was super cold), the coffee maker & the microwave. This microwave was nice! It had a USB & 3-prong plug on the front of it & when it stops running it's locked & you have to push the unlock button. If you are traveling with kids, this is a wonderful safety feature! We walked down to the docks twice on our overnight stay. There are chairs on the beach & on the dock. There were plenty of local places to eat, but I recommend C&Cs Wood Fired Pizza for their happy hour from 4-6 pm. A pizza (6 slices) & a pitcher for $10! At the Cottages, the staff were super nice. Irina & the other lady at check in were so helpful. I even asked a grounds person a question & he was helpful too. I don't care about super fancy. I care about CLEAN, a great view & beautiful surrounding. It's all of this & more!"
Stacy 1-night trip
Posted 18 hours ago
The Pelican Key Largo Cottages
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Private beach, easy access to restaurants, water sports, state parks, museums, groceries etc The staff is super friendly and helpful! The check in and check out was a breeze and there’s lots of open and covered parking for your vehicle! Great place for families to relax and unwind!"
Anil 3-night trip
Posted 21 hours ago
Reefhouse Resort & Marina
Gilbert's Resort

Gilbert's Resort

8/10 Good
"First visit. Holiday weekend quick getaway. Nice amenities, good food. Staff very friendly and helpful. Musical entertainment was great. Although, having a head banging heavy metal band on a Sunday afternoon was not the best choice on a holiday weekend. Security on property and actively engaged for guests safety. Overall a good experience and we will come back."
Kelly 3-night trip
Posted 1 day ago
Gilbert's Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Espectacular 🤗✨🤩 sigue siendo mi preferido"
Monica 1-night trip
Posted 1 day ago
Playa Largo Resort & Spa, Autograph Collection
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"This property was clean and the staff was very friendly. It is a cozy little get away in Key Largo with nice restaurants close by. Would definitely stay again."
P 2-night trip
Posted 9 days ago
Amoray Dive Resort
Azul del Mar

Azul del Mar

10/10 Excellent
"A amazing location with private beach swimming pool next door and restaurants nearby Ideal chill out spot"
Stephen 2-night trip
Posted 12 days ago
Azul del Mar

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.