A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Key Largo Luxury Hotels

Tonight
25 Oct - 26 Oct
Tomorrow
26 Oct - 27 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious living room with large windows, comfortable seating, and decorative plants.
An aerial view of a resort with a large pool, sun loungers, and palm trees.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
27 Oct - 28 Oct
Reefhouse Resort & Marina
An aerial view of a resort with a large pool, palm trees, and a beach.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 1,113
AED 1,455 total
includes taxes & fees
9 Nov - 10 Nov
Playa Largo Resort & Spa, Autograph Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 694
AED 1,050 total
includes taxes & fees
1 Nov - 2 Nov
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.
A beachfront hotel with multiple-story buildings, a pool, and palm trees.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,917
AED 2,398 total
includes taxes & fees
27 Oct - 28 Oct
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Absolutely loved our trip. The pelican reef was wonderful. The staff was excellent. It was clean comfortable and we really enjoyed the time we spent there."
kathy 7-night trip
Posted 3 hours ago
The Pelican Key Largo Cottages
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"I had a wonderful 7 day stay. The staff was outstanding. The breakfast buffet was good. The workers were prompt in maintaining the breakfast bar and quick to clean off a table. My room was clean and comfortable. The beach area could have used more sand because it had ruts in it from water flow, but there was ample seating. The pool area was nice. Lounge chairs, tables and chairs in good condition. Very nice outside tiki bar with plenty of seating as well. The sunsets from the beach area were amazing! If I ever travel back to Key Largo, I will stay here again."
Valerie 6-night trip
Posted 6 hours ago
Hampton Inn Key Largo Manatee Bay
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Unique location and pet friendly"
JACQUELINE 2-night trip
Posted 13 hours ago
Sunset Cove Beach Resort
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Great location. Pool was extremely warm and a bit cloudy due to suntan lotion. Floor in the suite was also dirty as in your feet will be covered in minutes"
Richard 2-night trip
Posted 23 hours ago
Bayside Inn Key Largo
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"😍"
Lisset 3-night trip
Posted 1 day ago
Waterside Suites & Marina
Azul del Mar

Azul del Mar

8/10 Good
"Property needs some maintenance"
DIANE 2-night trip
Posted 1 day ago
Azul del Mar
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"This place was awesome. Location, staff, property itself, all was excellent. Absolutely would come back and would highly recommend"
Rodrigo 1-night trip
Posted 1 day ago
Amoray Dive Resort

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.