Find Luxury Hotels in Key Largo, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Key Largo Luxury Hotels

Tonight
21 Apr - 22 Apr
Tomorrow
22 Apr - 23 Apr
This weekend
24 Apr - 26 Apr
Next weekend
1 May - 3 May

Our top choices for Key Largo luxury hotels

Exterior

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
The price is AED 1,319
AED 1,686 total
includes taxes & fees
12 May - 13 May
Playa Largo Resort & Spa, Autograph Collection
Property grounds

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,048 reviews)
  • cleanliness
    Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
The price is AED 1,382
AED 1,758 total
includes taxes & fees
4 May - 5 May
Baker's Cay Resort Key Largo, Curio Collection by Hilton
3 restaurants, breakfast, lunch, dinner served; American cuisine

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,409 reviews)
The price is AED 1,098
AED 1,382 total
includes taxes & fees
26 Apr - 27 Apr
Reefhouse Resort & Marina
On the beach, sun loungers, beach umbrellas, beach towels

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (74 reviews)
The price is AED 2,567
AED 3,091 total
includes taxes & fees
30 Apr - 1 May
The Islands of Islamorada
Balcony

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,318 reviews)
  • cleanliness
    Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
The price is AED 977
AED 1,368 total
includes taxes & fees
3 May - 4 May
Cheeca Lodge & Spa
Exterior

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
The price is AED 979
AED 1,349 total
includes taxes & fees
17 May - 18 May
Islander Resort
In-room safe, individually decorated, individually furnished

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (185 reviews)
  • cleanliness
    Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
The price is AED 1,098
AED 1,479 total
includes taxes & fees
4 May - 5 May
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Alligator Reef Oceanfront Room King Lanai with Queen Sofabed | View from room

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,267 reviews)
  • cleanliness
    Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
The price is AED 1,046
AED 1,446 total
includes taxes & fees
29 Apr - 30 Apr
Amara Cay Resort
Premium Cabin, Garden View | Terrace/patio

Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
4.0 star property
Homestead
9.2 out of 10, Wonderful, (11 reviews)
The price is AED 459
AED 1,101 total
includes taxes & fees
23 Apr - 24 Apr
Find Peace - Tiny House in Japanese Garden
Suite, 1 King Bed with Sofa bed, Ocean View | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,009 reviews)
The price is AED 810
AED 1,180 total
includes taxes & fees
26 Apr - 27 Apr
La Siesta Resort & Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

6/10 Okay
"Overly priced for a mediocre standard hotel. Parking we had to pay even for self parking!"
Marcus 2-night trip
Posted 3 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Explore a world of travel with Expedia

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
Known for its sunsets and boating, Key Largo also has some interesting things to see and do including Everglades National Park, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in Key Largo?
Reefhouse Resort & Marina is a luxury hotel with a private beach and 3 restaurants, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Playa Largo Resort & Spa, Autograph Collection.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Everglades National Park, Jimmy Johnson's Big Chill, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.