A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
24 Sep - 25 Sep
Tomorrow
25 Sep - 26 Sep
This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

Our top choices for Key Largo luxury hotels

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 966
AED 1,289 total
includes taxes & fees
8 Oct - 9 Oct
Playa Largo Resort & Spa, Autograph Collection

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
AED 977
AED 1,301 total
includes taxes & fees
1 Oct - 2 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 731
AED 969 total
includes taxes & fees
27 Sep - 28 Sep
Reefhouse Resort & Marina

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,488
AED 1,906 total
includes taxes & fees
1 Oct - 2 Oct
The Islands of Islamorada

5. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
AED 761
AED 1,125 total
includes taxes & fees
6 Oct - 7 Oct
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
AED 778
AED 1,124 total
includes taxes & fees
1 Oct - 2 Oct
Islander Resort

7. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 514
AED 847 total
includes taxes & fees
29 Sep - 30 Sep
Cheeca Lodge & Spa

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
AED 539
AED 875 total
includes taxes & fees
28 Sep - 29 Sep
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Amando este lugar muchas gracias Yoli por toda la atención volveremos pronto"
isoruma 1-night trip
Posted 1 hour ago
Playa Largo Resort & Spa, Autograph Collection
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Loved it so much my first trip I booked again! This stay was just as great as my last stay. Rooms were beautifully furnished with amazing views. Staff are super friendly- had another great stay! Will be back soon!"
Jacqueline 4-night trip
Posted 5 hours ago
Reefhouse Resort & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Great location !!"
Jenny 2-night trip
Posted 10 hours ago
Bayside Inn Key Largo
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"The place had character and culture that modern sterile resorts do not."
Wayne 1-night trip
Posted 20 hours ago
The Pelican Key Largo Cottages
Azul del Mar

Azul del Mar

10/10 Excellent
"This was a great place to stay"
Loney 1-night trip
Posted 1 day ago
Azul del Mar
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Nice hotel, continuing to update. Enjoyed the outdoor bar and sunset view. Beautiful location for sunset"
ANNA 1-night trip
Posted 2 days ago
Hampton Inn Key Largo Manatee Bay
Sunset Cove Beach Resort

Sunset Cove Beach Resort

8/10 Good
"Takes pets for reasonable rate; but no pool"
Deborah 2-night trip
Posted 2 days ago
Sunset Cove Beach Resort
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"What a great place. Rooms were very spacious for our family of 6 and you really feel in the keys with the decor. Swimming pool was nice and the little beach cove is beautiful. The deck and boats around are nice. The restaurant is very nice too. Would stay again."
Anthony 1-night trip
Posted 3 days ago
Gilbert's Resort
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

10/10 Excellent
"Key Largo is one of our favorite places. We try to stay in this Hotel because is a win win. Exceptional front desk, the hotel is clean and the amenities are wonderful. Thankfully."
Lisette 1-night trip
Posted 3 days ago
Marina Del Mar Resort and Marina

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.