A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
24 Aug - 25 Aug
Tomorrow
25 Aug - 26 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Our top choices for Key Largo luxury hotels

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
AED 931
AED 1,249 total
includes taxes & fees
21 Sep - 22 Sep
Baker's Cay Resort Key Largo, Curio Collection by Hilton

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 907
AED 1,223 total
includes taxes & fees
20 Sep - 21 Sep
Playa Largo Resort & Spa, Autograph Collection

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
25 Aug - 26 Aug
Reefhouse Resort & Marina

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,296
AED 1,686 total
includes taxes & fees
26 Aug - 27 Aug
The Islands of Islamorada

5. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
AED 794
AED 1,141 total
includes taxes & fees
2 Sep - 3 Sep
Islander Resort

6. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
AED 761
AED 1,125 total
includes taxes & fees
31 Aug - 1 Sep
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

7. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 547
AED 884 total
includes taxes & fees
27 Aug - 28 Aug
Cheeca Lodge & Spa

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
AED 537
AED 873 total
includes taxes & fees
30 Aug - 31 Aug
Amara Cay Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
AED 568
AED 907 total
includes taxes & fees
27 Aug - 28 Aug
La Siesta Resort & Villas
View all properties

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Espectacular"
Angélica Maria 1-night trip
Posted 11 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Azul del Mar

Azul del Mar

10/10 Excellent
"Place feels like home. Very clean abs quite."
damian 1-night trip
Posted 12 hours ago
Azul del Mar
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"Lo k no me gusto es el desayuno"
Omaida 2-night trip
Posted 14 hours ago
Gilbert's Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Hotel, location and amenities were great, but the staff and their friendliness was the best!"
Daniela 1-night trip
Posted 14 hours ago
Hampton Inn Key Largo Manatee Bay
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Excellent service from the cleaning staff and reception; a wonderful place to relax and enjoy days of sun and beach. Easy access to local restaurants. We love it and will return whenever we can—thanks to the entire staff."
luis 3-night trip
Posted 17 hours ago
The Pelican Key Largo Cottages
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Excellent room clean and staff was wonderful pool was perfect and water temp was cool for how warm it is"
Robert 2-night trip
Posted 2 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Reefhouse Resort & Marina is a luxury hotel with a private beach and 3 restaurants, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Playa Largo Resort & Spa, Autograph Collection.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.