A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
4 Oct - 5 Oct
Tomorrow
5 Oct - 6 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Key Largo luxury hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious living room with large windows, comfortable seating, and decorative plants.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
5 Oct - 6 Oct
Reefhouse Resort & Marina
An aerial view of a resort with a large pool, palm trees, and a beach.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 966
AED 1,289 total
includes taxes & fees
19 Oct - 20 Oct
Playa Largo Resort & Spa, Autograph Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.

3. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 636
AED 984 total
includes taxes & fees
19 Oct - 20 Oct
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,649
AED 2,090 total
includes taxes & fees
13 Oct - 14 Oct
The Islands of Islamorada
View all properties

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Beautiful property in Key Largo. We enjoyed our stay. Amanda at the Calusa bar is very good and welcoming. Downstairs bar service was hit or miss but all in all a wonderful experience. We will be back"
BLAINE 1-night trip
Posted 14 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Excelente"
Osletty 3-night trip
Posted 15 hours ago
Amoray Dive Resort
Gilbert's Resort

Gilbert's Resort

10/10 Excellent
"Good"
Eduardo 1-night trip
Posted 17 hours ago
Gilbert's Resort
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Excellent property, great location, clean rooms and very cozy. Very peaceful too! The front desk lady was awesome!!!!"
Gerardo 1-night trip
Posted 1 day ago
The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Always my to go place in the Keys! Very friendly staff. Clean rooms."
Lisandra 2-night trip
Posted 3 days ago
Bayside Inn Key Largo
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Great stay. Will stay there again"
Tim 1-night trip
Posted 3 days ago
Hampton Inn Key Largo Manatee Bay

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 4 restaurants and 3 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.