A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
14 Sep - 15 Sep
Tomorrow
15 Sep - 16 Sep
This weekend
18 Sep - 20 Sep
Next weekend
25 Sep - 27 Sep

Our top choices for Key Largo luxury hotels

Exterior
Serves lunch and dinner
Beach House, 3 Bedrooms, Pool Access, Bay View (Balcony/Patio, Private Pool) | Beach | On the beach, beach cabanas, sun loungers, beach umbrellas
3 restaurants; breakfast, lunch, dinner, and brunch served

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 937
AED 1,256 total
includes taxes & fees
27 Sep - 28 Sep
Playa Largo Resort & Spa, Autograph Collection
Exterior
Reception
2 outdoor pools, pool umbrellas, sun loungers
2 restaurants; breakfast, lunch, and dinner served

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
AED 870
AED 1,182 total
includes taxes & fees
28 Sep - 29 Sep
Baker's Cay Resort Key Largo, Curio Collection by Hilton
3 restaurants; breakfast, lunch, and dinner served
Private beach, white sand, sun loungers, beach umbrellas
Interior entrance
Poolside bar

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
15 Sep - 16 Sep
Reefhouse Resort & Marina
Daily cooked-to-order breakfast for a fee
Property grounds
2 outdoor pools, open 8:00 AM to 6:00 PM, sun loungers
Property grounds

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,488
AED 1,906 total
includes taxes & fees
15 Sep - 16 Sep
The Islands of Islamorada
Premium Cabin, Garden View | Terrace/patio
Premium Cabin, Garden View | Living room | 55-inch Smart TV with digital channels, Netflix, Hulu
Japanese garden
Premium Cabin, Garden View | Living room | 55-inch Smart TV with digital channels, Netflix, Hulu

5. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
AED 1,671
AED 2,470 total
includes taxes & fees
15 Sep - 16 Sep
Find Peace - Tiny House in Japanese Garden
Balcony
Poolside bar
Premium bedding, in-room safe, desk, laptop workspace
Property grounds

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 547
AED 884 total
includes taxes & fees
15 Sep - 16 Sep
Cheeca Lodge & Spa
Room, 1 King Bed, Balcony, Ocean View (Balcony) | Premium bedding, in-room safe, laptop workspace, iron/ironing board
Banquet hall
View from property
View from property

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
AED 673
AED 1,026 total
includes taxes & fees
20 Sep - 21 Sep
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Exterior
Poolside bar
3 restaurants; breakfast, lunch, dinner, and brunch served
View from room

8. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
AED 807
AED 1,155 total
includes taxes & fees
20 Sep - 21 Sep
Islander Resort
View from room
View from room
Outdoor pool, pool umbrellas, sun loungers
Room, 1 King Bed with Sofa bed, Oceanfront | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

9. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
AED 494
AED 824 total
includes taxes & fees
22 Sep - 23 Sep
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"1"
e 1-night trip
Posted 6 hours ago
Waterside Suites & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Clean rooms and staff was nice. We really liked the place. Will come back"
Cathy 1-night trip
Posted 13 hours ago
Amoray Dive Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"The hotel is very lovely and cozy, the entire staff is very friendly, and the areas and rooms are very clean; I recommend it."
juan 2-night trip
Posted 13 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Second time here and loved it. Free breakfast is great! Housekeeping is available via text which is helpful when you need anything! Clean property and nice beach."
Laureen 2-night trip
Posted 13 hours ago
Hampton Inn Key Largo Manatee Bay
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"It’s the perfect stay for a relaxing beach getaway."
Bonny 1-night trip
Posted 14 hours ago
The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

8/10 Good
"Clean, overall alright."
Celeuca 3-night trip
Posted 1 day ago
Bayside Inn Key Largo
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Excellent place!"
Douglas 2-night trip
Posted 2 days ago
Sunset Cove Beach Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Super good resorts"
Danilo 2-night trip
Posted 3 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.