The Best Luxury Hotels in Key Largo, FL from AED 480 in 2026

Check availability on Key Largo Luxury Hotels

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Our top choices for Key Largo luxury hotels

Playa Largo Resort & Spa, Autograph Collection

Rock Harbor

Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.

AED 1,521 total

includes taxes & fees

16 Jun - 17 Jun

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Key Largo

Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.

AED 1,358 total

includes taxes & fees

17 Jun - 18 Jun

3 restaurants; breakfast, lunch, and dinner served

Reefhouse Resort & Marina

Key Largo

AED 1,052 total

includes taxes & fees

22 Jun - 23 Jun

Cheeca Lodge & Spa

Matecumbe

Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.

AED 1,091 total

includes taxes & fees

4 Jun - 5 Jun

The Islands of Islamorada

Matecumbe

AED 2,682 total

includes taxes & fees

31 May - 1 Jun

In-room safe, individually decorated, individually furnished

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Islamorada

Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.

AED 1,459 total

includes taxes & fees

4 Jun - 5 Jun

Room, 1 King Bed with Sofa bed, Oceanfront (Alligator Reef, Lanai) | View from room

Amara Cay Resort

Matecumbe

Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.

AED 1,122 total

includes taxes & fees

9 Jun - 10 Jun

Islander Resort

Matecumbe

Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.

AED 1,178 total

includes taxes & fees

18 Jun - 19 Jun

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Top Key Largo Hotel Reviews

Bayside Inn Key Largo

6/10 Okay

"Adequate room with a comfortable bed. Did not like having to wear a plastic wristband which was hard to remove and aggrevated my skin in the heat."

Playa Largo Resort & Spa, Autograph Collection

8/10 Good

"Overall a very nice stay. We would have liked daily house keeping and overall more friendly staffing. All staff where doing what was needed but not all of them with heart behind the service. We also did not enjoy the comfort of the bed and pillows. The rooms and the resort are beautiful though and the atmosphere was fabulous. The pool is nice however daily cleaning of it would make it nicer. It seemed to need a shocking. The food was satisfactory to good however unlimited fresh water beverages bottled I feel would make the stay better. Something good or water wise did not always settle with us. Overall a nice stay. The Keys are a great area to travel and the sunsets are amazing. I rate it 3.5 out of 5."

Hampton Inn Key Largo Manatee Bay

8/10 Good

"The hotel was fine, location was decent. The main issues we had was that they were undergoing remodeling and the construction noises were a little annoying. Also, there is no Internet and the reception at least in the room we were seeing was next to nothing so we were needing to walk out into the parking lot to get some sort of reception. It seemed like the upgrades that they were doing. We’re going to be nice once the place is finished."

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Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?

Known for its sunsets and boating, Key Largo also has some interesting things to see and do including Everglades National Park, so you may want to take in the local sights during your visit.

What's the best high-end place to stay in Key Largo?

Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.

When can I expect good weather in Key Largo?

Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.

What's there to see and do in Key Largo?

Take in some sights and attractions while you're in Key Largo by visiting Everglades National Park, Jimmy Johnson's Big Chill, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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Check availability on Key Largo Luxury Hotels

Our top choices for Key Largo luxury hotels

Playa Largo Resort & Spa, Autograph Collection