A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
26 Aug - 27 Aug
Tomorrow
27 Aug - 28 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Our top choices for Key Largo luxury hotels

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
AED 961
AED 1,283 total
includes taxes & fees
14 Sep - 15 Sep
Baker's Cay Resort Key Largo, Curio Collection by Hilton

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
AED 907
AED 1,223 total
includes taxes & fees
20 Sep - 21 Sep
Playa Largo Resort & Spa, Autograph Collection

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
AED 804
AED 1,052 total
includes taxes & fees
27 Aug - 28 Aug
Reefhouse Resort & Marina

4. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
AED 547
AED 884 total
includes taxes & fees
2 Sep - 3 Sep
Cheeca Lodge & Spa

5. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
AED 1,296
AED 1,686 total
includes taxes & fees
27 Aug - 28 Aug
The Islands of Islamorada

6. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
AED 865
AED 1,221 total
includes taxes & fees
22 Sep - 23 Sep
Islander Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
AED 761
AED 1,125 total
includes taxes & fees
1 Sep - 2 Sep
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
AED 543
AED 880 total
includes taxes & fees
1 Sep - 2 Sep
Amara Cay Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
AED 568
AED 907 total
includes taxes & fees
30 Aug - 31 Aug
La Siesta Resort & Villas

10. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
AED 400
AED 1,034 total
includes taxes & fees
27 Aug - 28 Aug
Find Peace - Tiny House in Japanese Garden
View all properties

Top Key Largo Hotel Reviews

Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"The beach is private which adds a level of safety. The proximity of the pool to the beach front was very convenient. We had a great time at the Reefhouse and I will stay there again if I get back to Key Largo."
Gwen 6-night trip
Posted 4 hours ago
Reefhouse Resort & Marina
Azul del Mar

Azul del Mar

8/10 Good
"Nothing good to say about the drive and FL. However, the room: clean, comfy. No staff, really- just AI. It was good enough for our diving trip. The room was spacious but had thin walls (we heard the tenants next door all night). The groomed beach and dock wall out front were great."
Edward Patton 2-night trip
Posted 5 hours ago
Azul del Mar
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Clean room and staff"
Steve 3-night trip
Posted 9 hours ago
Waterside Suites & Marina
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

10/10 Excellent
"My go to spot in Key Largo. Great pool, great quiet location on the canal. Restaurants and bar right there. And free breakfast. 5stars!"
sandra 1-night trip
Posted 15 hours ago
Marina Del Mar Resort and Marina
Gilbert's Resort

Gilbert's Resort

8/10 Good
"Reviewed the time to be a little more up to date. Not bad, but not what I’m used to from a proper on the water. Great views though"
Princess 1-night trip
Posted 1 day ago
Gilbert's Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Excellent room clean and staff was wonderful pool was perfect and water temp was cool for how warm it is"
Robert 2-night trip
Posted 3 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.