A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Resorts & Hotels with Spas in Key Largo, FL

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Check availability on Key Largo Resorts & Hotels with Spas

Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Key Largo hotels with a spa

A hotel room with a bed, a dresser, a mirror, and a nightstand.
A beachfront property with a balcony overlooking the sea, palm trees, and a well-lit outdoor seating area.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A poolside area with blue chairs and a thatched-roof structure.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
AED 804
AED 1,052 total
includes taxes & fees
18 Oct - 19 Oct
Reefhouse Resort & Marina
A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A beachside resort with lounge chairs, a pool, and palm trees.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.
A beach with kayaks lined up near the water's edge, palm trees, and lounge chairs.

2. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
AED 590
AED 767 total
includes taxes & fees
18 Oct - 19 Oct
Kona Kai Resort and Gallery - Adults Only
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A modern living room with a view of the ocean, a comfortable chair, a small table, and a decorative plant.
A child sitting on a beach with sand toys and a green bucket nearby.
A beachfront hotel with multiple balconies, a pool, and a beach area with lounge chairs.

3. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
AED 1,081
AED 1,419 total
includes taxes & fees
28 Oct - 29 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.
A beachside patio with lounge chairs, a table, and a view of the ocean.
An aerial view of a resort with a large pool, palm trees, and a beach.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

4. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
AED 1,025
AED 1,355 total
includes taxes & fees
29 Oct - 30 Oct
Playa Largo Resort & Spa, Autograph Collection
A wooden table with two white cups, one with coffee and one with tea, placed on a body of water.
A room with a bed, two chairs, and a view of a lake.
A floating house with a thatched roof, a glass door, and a small deck area.
A couple in a room with a large window overlooking the sea, a bed with pillows, a small table with a vase of flowers, and a plant.

5. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
Key Largo
  • Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
AED 2,396
AED 2,695 total
includes taxes & fees
18 Oct - 19 Oct
Premium Floating Bungalow by Stay Ombi
A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A balcony with a view of palm trees and the sea, a white railing, and a table with chairs.

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
AED 665
AED 1,017 total
includes taxes & fees
19 Oct - 20 Oct
Cheeca Lodge & Spa
A hotel room with two beds, a large window with a view of a balcony, and a curtain on the window.
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.
A balcony with two wooden chairs and a small table, overlooking a beach with palm trees and the ocean.

7. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
  • Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
AED 1,917
AED 2,398 total
includes taxes & fees
18 Oct - 19 Oct
The Islands of Islamorada
View all properties

Choose what matters most at spa hotels in Key Largo

Pool
Hot tub
Breakfast included
Gym
5 stars

Top Key Largo Hotel Reviews

Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"The room was clean and the property was beautiful."
Darryl 2-night trip
Posted 7 hours ago
Reefhouse Resort & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Cute little place. Beautiful and convenient location near the state park and walkable to restaurants."
Kirsten 2-night trip
Posted 1 day ago
Amoray Dive Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Everything was amazing!!! Beautiful hotel and great location."
Jorge 4-night trip
Posted 3 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 4 restaurants, 3 bars, a 24-hour fitness center, and a hair salon. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1296 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a bit of extra time while you're in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.