The Best Adults Only Resorts & Hotels in Key West, FL from AED 455 in 2026 | Expedia

A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

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Check availability on Key West Adults Only Resorts & Hotels

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16 Oct - 18 Oct

Our top choices for Key West adults-only hotels

A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.

A two-story building with a white picket fence, a mailbox, and a small tree in front.

A hallway with a white door, a wooden bench, a blue sofa, and a staircase with a white railing.

A swimming pool with a mural of a dolphin and a butterfly, surrounded by lounge chairs and palm trees.

1. Duval House

Old Town Key West

United States

Christopher

AED 335

AED 455 total

includes taxes & fees

5 Oct - 6 Oct

A wooden deck with wicker furniture, a white staircase, and a lush garden area.

A bedroom with a large bed, a view of a swimming pool, and an open door leading to an outdoor seating area.

A two-story house with a balcony, surrounded by palm trees and a clear blue sky.

A hotel room with a large bed, a view of a swimming pool, and a balcony with outdoor seating.

2. Heron House - Adult Only

Old Town Key West

United States

Amanda

AED 442

AED 620 total

includes taxes & fees

4 Oct - 5 Oct

A poolside area with lounge chairs, a staircase leading to a balcony, and a pool.

A beige sofa with two pillows, flanked by two wooden side tables with lamps and potted plants, against a white wall with a framed picture of a tree.

A dining area with round tables and wicker chairs, a ceiling fan, and a bar area in the background.

A Southernmost Inn with a porch, a sign indicating vacancy, and a staircase leading to the entrance.

3. The Southernmost Inn - Adults Only

Old Town Key West

United States

Anthony

AED 350

AED 559 total

includes taxes & fees

5 Oct - 6 Oct

A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

A covered outdoor area with a wooden staircase, seating, and potted plants.

A bedroom with a bed, nightstand, lamp, air conditioning unit, and a no smoking sign.

A row of blue bicycles parked under a tree, with a white fence and a building in the background.

4. The Grand Guesthouse

Old Town Key West

United States

Travis

AED 560

AED 722 total

includes taxes & fees

4 Oct - 5 Oct

A tropical outdoor area with palm trees, hanging plants, and string lights.

An outdoor patio with a table and chairs, surrounded by lush greenery and string lights.

A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.

A large, two-story building with a balcony, surrounded by dense tropical foliage.

5. Douglas House - Adults Only

Old Town Key West

United States

Maricela

AED 491

AED 608 total

includes taxes & fees

5 Oct - 6 Oct

A spacious room with a wooden floor, white furniture, and large windows.

A paved pathway surrounded by lush greenery and palm trees.

A white building with a covered porch, potted plants, and a white picket fence.

A modern living room with a sofa, two armchairs, a coffee table, and a small table with a lamp. There is a large window with shutters, an air conditioning unit, and a view of greenery outside.

6. Paradise Inn Key West - Adults Only

Old Town Key West

United States

Mary

AED 466

AED 705 total

includes taxes & fees

4 Oct - 5 Oct

A bathroom with a double sink, a bathtub, and a large mirror.

A large, ornate hotel with a pool, palm trees, and a view of the ocean.

A gated entrance with a blue metal gate, palm trees, and a building with a red roof in the background.

A large, two-story house with a prominent tower and a covered porch.

7. Southernmost House - Adult Exclusive

Old Town Key West

United States

yessy

AED 512

AED 1,040 total

includes taxes & fees

26 Oct - 27 Oct

A wooden deck with wicker furniture and a white railing, surrounded by lush tropical vegetation.

A two-story building with a white picket fence, palm trees, and a clear blue sky.

A breakfast tray with croissants, orange juice, and coffee on a table by a window with a view of a pool and greenery.

A swimming pool with a white picket fence, surrounded by lounge chairs and potted plants.

8. Weatherstation Inn

Old Town Key West

United States

Svetlana

AED 731

AED 822 total

includes taxes & fees

12 Oct - 13 Oct

View all properties

Top Key West Hotel Reviews

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent

"Amazing!"

Pier House Resort & Spa

Pier House Resort & Spa

8/10 Good

"Location is great if you want to be close to the action. But, it is also quite and laid out well for beach bumming. Iguanas and chickens are everywhere!"

Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

8/10 Good

"Valet parking obligatoire ce qui était pour nous plutôt une nuisance qu’un avantage car nous sortions souvent visiter les alentours! Nous ne pouvions pas apporter de boissons alcoolisé au bord de la piscine il fallait les acheter directement au bar de piscine …"