The Best Adults Only Resorts & Hotels in Key West, FL from AED 356 in 2026 | Expedia

A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

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Check availability on Key West Adults Only Resorts & Hotels

Tonight

14 Sep - 15 Sep

Tomorrow

15 Sep - 16 Sep

This weekend

18 Sep - 20 Sep

Next weekend

25 Sep - 27 Sep

Our top choices for Key West adults-only hotels

Property grounds

Garden

Duval Duplex 2 bedrooms 25 ft Balcony (Adults Only) | Living area | 43-inch flat-screen TV with cable channels, TV

View from property

1. Duval House

Old Town Key West

United States

Robert

AED 338

AED 459 total

includes taxes & fees

16 Sep - 17 Sep

Exterior

Garden

Fish Tail Palm Premium King Suite, 1King bed, Large Patio area in Garden, Ground Floor | Iron/ironing board, WiFi (free), individually decorated

Courtyard

2. Douglas House - Adults Only

Old Town Key West

United States

michael

AED 288

AED 356 total

includes taxes & fees

16 Sep - 17 Sep

Building design

Southernmost King Suite | Iron/ironing board, individually decorated, individually furnished

Courtyard

Dining

3. The Southernmost Inn - Adults Only

Old Town Key West

United States

Ron

AED 245

AED 441 total

includes taxes & fees

15 Sep - 16 Sep

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Free daily continental breakfast

Front of property

Lobby

4. Almond Tree Inn Hotel - Adults Only

Old Town Key West

United States

John

AED 587

AED 660 total

includes taxes & fees

15 Sep - 16 Sep

Porch

Exterior

Exterior

In-room safe, desk, iron/ironing board, WiFi (free)

5. Heron House - Adult Only

Old Town Key West

United States

Natalia

AED 427

AED 603 total

includes taxes & fees

15 Sep - 16 Sep

11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, iron/ironing board, WiFi (free)

Poinciana Patio, Pool View, Patio - Adult Only | Terrace/patio

Poinciana Patio, Pool View, Patio - Adult Only | Terrace/patio

Sports facility

6. Tropical Inn

Old Town Key West

United States

Anthony

AED 354

AED 490 total

includes taxes & fees

15 Sep - 16 Sep

Superior Studio Suite, 1 King Bed with Sofa bed, Accessible, Refrigerator & Microwave | WiFi (free), bed sheets

Premier Suite, 1 King Bed with Sofa bed, Patio, Garden Area (Room 16) | Living area | Flat-screen TV

Outdoor pool, sun loungers

Free continental breakfast

7. Alexander's Guesthouse - Adult Exclusive

Old Town Key West

United States

Justin

AED 327

AED 506 total

includes taxes & fees

15 Sep - 16 Sep

Exterior

Lunch and dinner served

Front of property - evening/night

Interior entrance

8. Southernmost House - Adult Exclusive

Old Town Key West

United States

yessy

AED 563

AED 1,098 total

includes taxes & fees

12 Oct - 13 Oct

View all properties

Top Key West Hotel Reviews

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent

"Pools were well maintained but crowded. Property was beautiful. Staff was helpful. Breakfast was very good."

Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent

"Best location in Key West. The private beach and service on the beach are the best"