The Best Adults Only Resorts & Hotels in Key West, FL from AED 464 in 2026 | Expedia

A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Key West Adults Only Resorts & Hotels

Tonight

21 Sep - 22 Sep

Tomorrow

22 Sep - 23 Sep

This weekend

25 Sep - 27 Sep

Next weekend

Our top choices for Key West adults-only hotels

Property grounds

A heated pool, sun loungers

Garden

Duval Duplex 2 bedrooms 25 ft Balcony (Adults Only) | Living area | 43-inch flat-screen TV with cable channels, TV

1. Duval House

Old Town Key West

United States

Anne

AED 353

AED 476 total

includes taxes & fees

27 Sep - 28 Sep

11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, iron/ironing board, WiFi (free)

Poinciana Patio, Pool View, Patio - Adult Only | Terrace/patio

Poinciana Patio, Pool View, Patio - Adult Only | Terrace/patio

Sports facility

2. Tropical Inn

Old Town Key West

United States

Molly

AED 354

AED 490 total

includes taxes & fees

27 Sep - 28 Sep

Building design

Exterior

Southernmost King Suite | Iron/ironing board, individually decorated, individually furnished

Courtyard

3. The Southernmost Inn - Adults Only

Old Town Key West

United States

ANDREW

AED 262

AED 459 total

includes taxes & fees

23 Sep - 24 Sep

Courtyard

Property grounds

A Queen Room | Premium bedding, pillowtop beds, iron/ironing board, WiFi (free)

Bicycling

4. The Grand Guesthouse

Old Town Key West

United States

Alissa

AED 414

AED 558 total

includes taxes & fees

24 Sep - 25 Sep

Exterior

Courtyard

Garden

Courtyard

5. Douglas House - Adults Only

Old Town Key West

United States

michael

AED 375

AED 464 total

includes taxes & fees

24 Sep - 25 Sep

Porch

Exterior

Exterior

View from room

6. Heron House - Adult Only

Old Town Key West

United States

Fernando

AED 427

AED 603 total

includes taxes & fees

23 Sep - 24 Sep

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Free daily continental breakfast

Lobby

Front of property

7. Almond Tree Inn Hotel - Adults Only

Old Town Key West

United States

John

AED 599

AED 673 total

includes taxes & fees

27 Sep - 28 Sep

Property grounds

Sundeck

Front of property

Deluxe ADA Queen Room | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe

8. Orchid Key Inn - Adults Only

Old Town Key West

United States

Nicholas

AED 560

AED 630 total

includes taxes & fees

27 Sep - 28 Sep

View all properties

Top Key West Hotel Reviews

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent

"A little annoyed at the gate that got locked (leading us to our room), and that the gate was not repaired during our stay, but that was the only real issue out of the entire stay."