The Best Adults Only Resorts & Hotels in Key West, FL from AED 538 in 2026 | Expedia

A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

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Check availability on Key West Adults Only Resorts & Hotels

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16 Oct - 18 Oct

Our top choices for Key West adults-only hotels

A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.

A hallway with a white door, a wooden bench, a blue sofa, and a staircase with a white railing.

A two-story building with a white picket fence, a mailbox, and a small tree in front.

A swimming pool with a mural of a dolphin and a butterfly, surrounded by lounge chairs and palm trees.

1. Duval House

Old Town Key West

United States

Christopher

AED 639

AED 797 total

includes taxes & fees

14 Oct - 15 Oct

A poolside area with lounge chairs, a staircase leading to a balcony, and a pool.

A Southernmost Inn with a porch, a sign indicating vacancy, and a staircase leading to the entrance.

A dining area with round tables and wicker chairs, a ceiling fan, and a bar area in the background.

A beige sofa with two pillows, flanked by two wooden side tables with lamps and potted plants, against a white wall with a framed picture of a tree.

2. The Southernmost Inn - Adults Only

Old Town Key West

United States

Anthony

AED 408

AED 625 total

includes taxes & fees

13 Oct - 14 Oct

A tropical outdoor area with palm trees, hanging plants, and string lights.

A large, two-story building with a balcony, surrounded by dense tropical foliage.

A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.

A wooden deck with lush greenery and a pool area.

3. Douglas House - Adults Only

Old Town Key West

United States

Maricela

AED 491

AED 608 total

includes taxes & fees

8 Oct - 9 Oct

A wooden deck with wicker furniture, a white staircase, and a lush garden area.

A hotel room with a large bed, a view of a swimming pool, and a balcony with outdoor seating.

A two-story house with a balcony, surrounded by palm trees and a clear blue sky.

A bedroom with a large bed, a view of a swimming pool, and an open door leading to an outdoor seating area.

4. Heron House - Adult Only

Old Town Key West

United States

Amanda

AED 442

AED 620 total

includes taxes & fees

11 Oct - 12 Oct

A large, ornate hotel with a pool, palm trees, and a view of the ocean.

A large, two-story house with a prominent tower and a covered porch.

A grand staircase with ornate railings and a chandelier.

A balcony with white railings and a table, overlooking a beach with palm trees and a clear blue sky.

5. Southernmost House - Adult Exclusive

Old Town Key West

United States

yessy

AED 512

AED 1,040 total

includes taxes & fees

25 Oct - 26 Oct

A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

A row of blue bicycles parked under a tree, with a white fence and a building in the background.

A covered outdoor area with a wooden staircase, seating, and potted plants.

A bedroom with a bed, nightstand, lamp, air conditioning unit, and a no smoking sign.

6. The Grand Guesthouse

Old Town Key West

United States

Travis

AED 543

AED 703 total

includes taxes & fees

14 Oct - 15 Oct

A spacious room with a wooden floor, white furniture, and large windows.

A modern living room with a sofa, two armchairs, a coffee table, and a small table with a lamp. There is a large window with shutters, an air conditioning unit, and a view of greenery outside.

A covered outdoor area with a table and chairs, surrounded by white railings and green foliage.

A paved pathway surrounded by lush greenery and palm trees.

7. Paradise Inn Key West - Adults Only

Old Town Key West

United States

Mary

AED 518

AED 766 total

includes taxes & fees

14 Oct - 15 Oct

A wooden deck with wicker furniture and a white railing, surrounded by lush tropical vegetation.

A pathway leading to a building with a white facade, surrounded by lush greenery and palm trees.

A two-story building with a white picket fence, palm trees, and a clear blue sky.

A swimming pool with a white picket fence, surrounded by lounge chairs and potted plants.

8. Weatherstation Inn

Old Town Key West

United States

Robert

AED 621

AED 698 total

includes taxes & fees

8 Oct - 9 Oct

View all properties

Top Key West Hotel Reviews

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

10/10 Excellent

"I did hear roosters, but that's part of the charm of Key West. There was occasional chicken poop on the floors outside, so that's why I gave a 4 for cleanliness, but they do seem to clean it up fairly quickly. Overall I loved the stay. I will go again."

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent

"Perfect! Great surroundings, staff & people! Convenient to get to everything!"

Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

10/10 Excellent

"Great place definitely staying there next time"