The Best Adults Only Resorts & Hotels in Key West, FL from AED 692 in 2026 | Expedia

A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Key West Adults Only Resorts & Hotels

Tonight

19 Oct - 20 Oct

Tomorrow

20 Oct - 21 Oct

This weekend

23 Oct - 25 Oct

Next weekend

Our top choices for Key West adults-only hotels

A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.

A lush garden with a variety of tropical plants and a paved walkway.

A two-story building with a white picket fence, a mailbox, and a small tree in front.

A swimming pool with a mural of a dolphin and a butterfly, surrounded by lounge chairs and palm trees.

1. Duval House

Old Town Key West

United States

Cathrine

AED 621

AED 777 total

includes taxes & fees

25 Oct - 26 Oct

A wooden deck with wicker furniture, a white staircase, and a lush garden area.

A hotel entrance with a sign reading "Heron House Office."

A two-story house with a balcony, surrounded by palm trees and a clear blue sky.

A bedroom with a large bed, a view of a swimming pool, and an open door leading to an outdoor seating area.

2. Heron House - Adult Only

Old Town Key West

United States

Lance

AED 584

AED 783 total

includes taxes & fees

25 Oct - 26 Oct

A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

A covered outdoor area with a wooden staircase, seating, and potted plants.

A two-story building with a porch, a sign reading "The Grand Guesthouse," and a purple flag.

A row of blue bicycles parked under a tree, with a white fence and a building in the background.

3. The Grand Guesthouse

Old Town Key West

United States

Justyn

AED 578

AED 742 total

includes taxes & fees

27 Oct - 28 Oct

A poolside area with lounge chairs, a staircase leading to a balcony, and a pool.

An outdoor patio with tables and chairs, surrounded by trees and a house.

A dining area with round tables and wicker chairs, a ceiling fan, and a bar area in the background.

A beige sofa with two pillows, flanked by two wooden side tables with lamps and potted plants, against a white wall with a framed picture of a tree.

4. The Southernmost Inn - Adults Only

Old Town Key West

United States

Anthony

AED 474

AED 698 total

includes taxes & fees

25 Oct - 26 Oct

A spacious room with a wooden floor, white furniture, and large windows.

A white building with a covered porch, potted plants, and a white picket fence.

A modern living room with a sofa, two armchairs, a coffee table, and a small table with a lamp. There is a large window with shutters, an air conditioning unit, and a view of greenery outside.

A paved pathway surrounded by lush greenery and palm trees.

5. Paradise Inn Key West - Adults Only

Old Town Key West

United States

Meghan

AED 455

AED 692 total

includes taxes & fees

27 Oct - 28 Oct

A large, ornate hotel with a pool, palm trees, and a view of the ocean.

A balcony with white railings and a table, overlooking a beach with palm trees and a clear blue sky.

A large, two-story house with a prominent tower and a covered porch.

A grand staircase with ornate railings and a chandelier.

6. Southernmost House - Adult Exclusive

Old Town Key West

United States

Amy

AED 658

AED 1,205 total

includes taxes & fees

25 Oct - 26 Oct

A tropical outdoor area with palm trees, hanging plants, and string lights.

A wooden deck with lush greenery and a pool area.

An outdoor patio with a table and chairs, surrounded by lush greenery and string lights.

A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.

7. Douglas House - Adults Only

Old Town Key West

United States

Maricela

AED 578

AED 715 total

includes taxes & fees

27 Oct - 28 Oct

A wooden deck with wicker furniture and a white railing, surrounded by lush tropical vegetation.

A pathway leading to a building with a white facade, surrounded by lush greenery and palm trees.

A two-story building with a white picket fence, palm trees, and a clear blue sky.

A swimming pool with a white picket fence, surrounded by lounge chairs and potted plants.

8. Weatherstation Inn

Old Town Key West

United States

Robert

AED 804

AED 905 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Top Key West Hotel Reviews

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

8/10 Good

"Great location on the water"

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

10/10 Excellent

"Booked here last minute due to our Vrbo being canceled - Can't say enough nice things about it! - Yes, the rooms are very small and the hallways are a bit older but this place is gorgeous! Pools are excellent and the staff is too. Only thing is if you like breakfast, go out. It's bland and boring at best."

Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent

"Everything was exceptional at Pier House. Breakfast by the water every morning great music and drinks from the bar, well maintained property and beach! Staff went out of their way and were very kimd. Our room with lanai was fantastic! Thank you Pier House!"