A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

Find Adults Only Resorts & Hotels in Key West, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Key West Adults Only Resorts & Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Key West adults-only hotels

A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.
A lush garden with a variety of tropical plants and a paved walkway.
A hallway with a white door, a wooden bench, a blue sofa, and a staircase with a white railing.
A swimming pool with a mural of a dolphin and a butterfly, surrounded by lounge chairs and palm trees.

1. Duval House

Duval House
Old Town Key West
United States
Cathrine
AED 621
AED 777 total
includes taxes & fees
25 Oct - 26 Oct
Duval House
A spacious room with a wooden floor, white furniture, and large windows.
A paved pathway surrounded by lush greenery and palm trees.
A modern living room with a sofa, two armchairs, a coffee table, and a small table with a lamp. There is a large window with shutters, an air conditioning unit, and a view of greenery outside.
A covered outdoor area with a table and chairs, surrounded by white railings and green foliage.

2. Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only
Old Town Key West
United States
Meghan
AED 453
AED 690 total
includes taxes & fees
28 Oct - 29 Oct
Paradise Inn Key West - Adults Only
A poolside area with lounge chairs, a staircase leading to a balcony, and a pool.
A beige sofa with two pillows, flanked by two wooden side tables with lamps and potted plants, against a white wall with a framed picture of a tree.
A Southernmost Inn with a porch, a sign indicating vacancy, and a staircase leading to the entrance.
An outdoor patio with tables and chairs, surrounded by trees and a house.

3. The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
Old Town Key West
United States
Anthony
AED 474
AED 698 total
includes taxes & fees
25 Oct - 26 Oct
The Southernmost Inn - Adults Only
A wooden deck with wicker furniture, a white staircase, and a lush garden area.
A hotel entrance with a sign reading "Heron House Office."
A two-story house with a balcony, surrounded by palm trees and a clear blue sky.
A bedroom with a large bed, a view of a swimming pool, and an open door leading to an outdoor seating area.

4. Heron House - Adult Only

Heron House - Adult Only
Old Town Key West
United States
Amanda
AED 644
AED 853 total
includes taxes & fees
25 Oct - 26 Oct
Heron House - Adult Only
A large, ornate hotel with a pool, palm trees, and a view of the ocean.
A grand staircase with ornate railings and a chandelier.
A balcony with white railings and a table, overlooking a beach with palm trees and a clear blue sky.
A large, two-story house with a prominent tower and a covered porch.

5. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
Old Town Key West
United States
Amy
AED 658
AED 1,205 total
includes taxes & fees
25 Oct - 26 Oct
Southernmost House - Adult Exclusive
A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.
A two-story building with a porch, a sign reading "The Grand Guesthouse," and a purple flag.
A bedroom with a bed, nightstand, lamp, air conditioning unit, and a no smoking sign.
A row of blue bicycles parked under a tree, with a white fence and a building in the background.

6. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West
United States
Justyn
AED 578
AED 742 total
includes taxes & fees
27 Oct - 28 Oct
The Grand Guesthouse
A tropical outdoor area with palm trees, hanging plants, and string lights.
A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.
A wooden deck with lush greenery and a pool area.
A large, two-story building with a balcony, surrounded by dense tropical foliage.

7. Douglas House - Adults Only

Douglas House - Adults Only
Old Town Key West
United States
Maricela
AED 546
AED 676 total
includes taxes & fees
28 Oct - 29 Oct
Douglas House - Adults Only
A bedroom with a four-poster bed, a wooden desk, wicker chairs, and a view of the outdoors.
A breakfast buffet with a variety of fruits, pastries, and beverages on a wooden deck with a view of a lush garden and a pool.
A pool area with lounge chairs and candles, surrounded by palm trees and a building in the background.
A cozy room with a wicker chair, a small table with a bottle and glasses, and a view of a yellow room through an open door.

8. Tropical Inn

Tropical Inn
Old Town Key West
United States
Natalie
AED 745
AED 930 total
includes taxes & fees
29 Oct - 30 Oct
Tropical Inn
A green house with a white porch, a flag, and a sign advertising a property for sale.
A bathroom with a vanity, a mirror, and a window with blinds.
A bedroom with a large bed, a sofa, a nightstand, and a painting on the wall.
A room with a ceiling fan, an air conditioning unit, a window with blinds, a sofa with patterned cushions, a small round table, and a floor lamp.

9. L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
Key West Historic District
United States
Richard
AED 625
AED 703 total
includes taxes & fees
28 Oct - 29 Oct
L'Habitation Guest House - Adults Only
A modern hotel room with a white sofa, a zebra-patterned rug, and a large mirror above the sofa.
A pool area with lounge chairs, a pool, and a building with a balcony and outdoor seating.
A narrow room with a bed, a potted plant, and a window with blinds.
A spacious living room with a sofa, chairs, and a dining table. There are large windows with blinds, a door leading to a patio, and a ceiling with exposed beams.

10. Alexander's Guesthouse - Adult Exclusive

Alexander's Guesthouse - Adult Exclusive
Old Town Key West
United States
Nestor
AED 658
AED 887 total
includes taxes & fees
18 Oct - 19 Oct
Alexander's Guesthouse - Adult Exclusive
View all properties

Top Key West Hotel Reviews

Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

10/10 Excellent
"The staff is amazing. Super welcoming and they gave me a great layout of what the hotel had to offer. The wallet John was a class act I really appreciated his help particularly. I only went to 2 of the 4 pools but they were clean and relaxing. The food truck had some surprisingly good food, and the bar was good too. You can walk the little beach they have here, layout and relax in the hammocks, and if you want to hang in the room there is plenty in there as well. Location wise there is a Walgreens within walking distance and there are two large shopping plazas within a quarter of a mile so you have plenty of options for food or items for the room. The shuttle service to the beach and to Duval Street came in clutch as well. If you are looking for a place that is a little quieter to sleep at than Duval but close to the action this is the place. I will certainly stay here again when in the area."
Joshua 2-night trip
Posted 3 hours ago
Parrot Key Hotel & Villas
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

8/10 Good
"👍"
Peter 1-night trip
Posted 12 hours ago
Southernmost Beach Resort and Guesthouses
Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent
"This resort has everything with the best hospitality! I highly recommend this resort for anyone that wants to enjoy Key West with total relaxation! 😎"
Nikki 5-night trip
Posted 17 hours ago
Pier House Resort & Spa
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

10/10 Excellent
"Great property"
Charlene 3-night trip
Posted 2 days ago
Casa Marina Key West, Curio Collection by Hilton