The Best Hotels Closest to Lewis and Clark Trail Trailhead in St. Louis for 2026

Our top choices for Lewis and Clark Trail Trailhead hotels

Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

3.2 km from Lewis and Clark Trail Trailhead

FERNANDO

AED 356 total

includes taxes & fees

25 May - 26 May

Holiday Inn Express St. Louis West - O'Fallon by IHG

3.2 km from Lewis and Clark Trail Trailhead

Kayla

AED 477 total

includes taxes & fees

26 May - 27 May

TownePlace Suites by Marriott St. Louis Chesterfield

5.8 km from Lewis and Clark Trail Trailhead

Megan

AED 496 total

includes taxes & fees

28 May - 29 May

Staybridge Suites O'Fallon Chesterfield by IHG

3.2 km from Lewis and Clark Trail Trailhead

Renee

AED 542 total

includes taxes & fees

14 Jun - 15 Jun

Residence Inn by Marriott O'Fallon

3.6 km from Lewis and Clark Trail Trailhead

Charles

AED 568 total

includes taxes & fees

14 Jun - 15 Jun

Hilton Garden Inn St. Louis/O'Fallon MO

7.1 km from Lewis and Clark Trail Trailhead

Michael

AED 626 total

includes taxes & fees

31 May - 1 Jun

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

10.3 km from Lewis and Clark Trail Trailhead

Freddie

AED 521 total

includes taxes & fees

25 May - 26 May

Drury Plaza Hotel St. Louis Chesterfield

14.8 km from Lewis and Clark Trail Trailhead

Alan

AED 554 total

includes taxes & fees

25 May - 26 May

Hyatt Place St. Louis/Chesterfield

14.9 km from Lewis and Clark Trail Trailhead

Kayla

AED 592 total

includes taxes & fees

31 May - 1 Jun

Drury Inn & Suites St. Louis St. Peters

15 km from Lewis and Clark Trail Trailhead

Admir

AED 469 total

includes taxes & fees

25 May - 26 May

Hampton Inn & Suites St. Louis/Chesterfield

10.9 km from Lewis and Clark Trail Trailhead

Darin

AED 435 total

includes taxes & fees

31 May - 1 Jun

The Wildwood Hotel

14.7 km from Lewis and Clark Trail Trailhead

kathy

AED 377 total

includes taxes & fees

25 May - 26 May

In-room safe, desk, laptop workspace, blackout drapes

TownePlace Suites by Marriott Wentzville

17 km from Lewis and Clark Trail Trailhead

Amy

AED 714 total

includes taxes & fees

24 May - 25 May

SpringHill Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Alejandro

AED 635 total

includes taxes & fees

21 May - 22 May

Residence Inn by Marriott St. Louis Chesterfield

12.4 km from Lewis and Clark Trail Trailhead

Jessica

AED 812 total

includes taxes & fees

25 May - 26 May

WoodSpring Suites St Peters-OFallon

13.6 km from Lewis and Clark Trail Trailhead

Roxanne

AED 319 total

includes taxes & fees

8 Jun - 9 Jun

Holiday Inn Express & Suites St Peters by IHG

13.4 km from Lewis and Clark Trail Trailhead

John

AED 495 total

includes taxes & fees

31 May - 1 Jun

Standard Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, laptop workspace, blackout drapes

Comfort Inn & Suites Chesterfield - St. Louis

6.6 km from Lewis and Clark Trail Trailhead

Janiece

AED 397 total

includes taxes & fees

27 May - 28 May

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Jeff

AED 431 total

includes taxes & fees

31 May - 1 Jun

DoubleTree by Hilton Hotel St. Louis - Chesterfield

13.9 km from Lewis and Clark Trail Trailhead

David

AED 612 total

includes taxes & fees

14 Jun - 15 Jun

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Compare popular hotels close to Lewis and Clark Trail Trailhead

Property	Property class	Guest rating
Sleep Inn & Suites O'Fallon MO - Technology Drive	2.5 star property	9.0 Wonderful 1,000 reviews	View
Holiday Inn Express St. Louis West - O'Fallon by IHG	2.5 star property	8.6 Excellent 926 reviews	View
TownePlace Suites by Marriott St. Louis Chesterfield	3.0 star property	9.0 Wonderful 297 reviews	View
Staybridge Suites O'Fallon Chesterfield by IHG	3.0 star property	8.6 Excellent 435 reviews	View
Residence Inn by Marriott O'Fallon	3.0 star property	8.4 Very Good 473 reviews	View

Top Lewis and Clark Trail Trailhead Hotel Reviews

Sonesta ES Suites St. Louis - Chesterfield

4/10 Poor

"The rooms were not clean. Getting in the room was a challenge…lock assembly didn’t work properly and cards didn’t work half the time. Rooms were not clean. Staff not all that helpful. Food was subpar. "

Ameristar Casino Resort and Spa

8/10 Good

"The room was very spacious and the bathroom was also. One of our tv remotes didnʻt work. I wish there was on site laundry and I wish the pool was kid friendly on the weekend at least during the daytime hours, however I understand it is a Casino gaming hotel but I think that would be a great adjustment. I was surprised there werenʻt more on site restaurants available, and I also wish we had access to all the restaurants because the one we really wanted to try and made reservations for before realizing it was inside the casino. The front desk staff was always amazing and very sweet and helpful! Would definitely stay here again, very convenient location to everything we had planned on this trip!"

Best Western Plus St. Louis West-Westport

8/10 Good

"The room was clean, but door to bathroom would not close easily. Looked like it had previously been shaved down some and reported to front desk upon check out. Breakfast was good, good variety with hot choices. Parking was good, with good lighting. Overall good stay. Granddaughter disappointed the pool was not open. Ice maker on second floor out of order bit of a hassle with one elevator."

Comfort Suites St Charles - St Louis

4/10 Poor

"Room was clean, staff was accommodating but the blinds in our room were broke with no black outs, the AC unit didn’t work correctly and it squeaked so loud while sleeping, that we didn’t sleep. And then were up at 5:45am when the sun started coming through the window. Few items in our bathroom breaking. The size however was great but the price was not reflective of the quality. "

La Quinta Inn & Suites by Wyndham St. Louis Westport

10/10 Excellent

"parking lot was full. I was not sure if the lot to the side was part of the hotel, as it was not marked in anyway nor did the staff alert me to the face that is was extra parking space. I was only told that in no way was I to use the parking area of the place next door. "

Sleep Inn & Suites O'Fallon MO - Technology Drive

8/10 Good

"Thermostat didn’t work. Back entrance wasn’t always locked. Ate breakfast about 8AM, hot items were like warm. Staff were very professional and attentive, but I called to see if I would be able to check in a little early and was told there would be a $30 charge "

Hotels near other Lewis and Clark Trail Trailhead attractions

August A. Busch Memorial Conservation Area

4.3/5 (7 reviews)

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?

Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 27 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Lewis and Clark Trail Trailhead?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2 mi (3.2 km) from Lewis and Clark Trail Trailhead. Other good options around the area include The Wildwood Hotel and WoodSpring Suites St Peters-OFallon.

How many hotels can I expect to find near Lewis and Clark Trail Trailhead?

Expedia has 27 hotels and other accommodations a few miles from Lewis and Clark Trail Trailhead.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?

Yes, most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available near Lewis and Clark Trail Trailhead.

Where can I learn more about changing or cancelling my trip in the area near Lewis and Clark Trail Trailhead?

For more details about picking new dates or cancelling your stay near Lewis and Clark Trail Trailhead, click here.

What can I see and do near Lewis and Clark Trail Trailhead?

Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Babler State Park, and Golf Headquarters are worth a stop while you're in the area. St. Louis Premium Outlets and Weldon Spring Site Interpretive Center are both worth a visit while you're checking out the area.

Find hotels near Lewis and Clark Trail Trailhead, St. Louis from AED 319

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Our top choices for Lewis and Clark Trail Trailhead hotels

Sleep Inn & Suites O'Fallon MO - Technology Drive

Holiday Inn Express St. Louis West - O'Fallon by IHG

TownePlace Suites by Marriott St. Louis Chesterfield

Staybridge Suites O'Fallon Chesterfield by IHG

Residence Inn by Marriott O'Fallon

Hilton Garden Inn St. Louis/O'Fallon MO

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Drury Plaza Hotel St. Louis Chesterfield

Hyatt Place St. Louis/Chesterfield

Drury Inn & Suites St. Louis St. Peters

Hampton Inn & Suites St. Louis/Chesterfield

The Wildwood Hotel

TownePlace Suites by Marriott Wentzville

SpringHill Suites by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield

WoodSpring Suites St Peters-OFallon

Holiday Inn Express & Suites St Peters by IHG

Comfort Inn & Suites Chesterfield - St. Louis

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

Compare popular hotels close to Lewis and Clark Trail Trailhead

Top Lewis and Clark Trail Trailhead Hotel Reviews

Sonesta ES Suites St. Louis - Chesterfield

Hotels near other Lewis and Clark Trail Trailhead attractions

August A. Busch Memorial Conservation Area

Frequently asked questions

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