The Best Hotels Closest to Mark Twain Boyhood Home and Museum in Hannibal for 2026

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Our top choices for Mark Twain Boyhood Home and Museum hotels

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A compact kitchen with a refrigerator, microwave, and sink.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

1. Riverside Inn Hannibal

0.2 km from Mark Twain Boyhood Home and Museum

Janee

AED 557

AED 770 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A swimming pool with lounge chairs and a covered seating area.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

2. Lighthouse Inn & Suites

0.6 km from Mark Twain Boyhood Home and Museum

Connie

AED 585

AED 802 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

3. Best Western On The River

< 0.1 km from Mark Twain Boyhood Home and Museum

Wei

AED 404

AED 466 total

includes taxes & fees

21 Oct - 22 Oct

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

4. Garden House Bed and Breakfast

0.3 km from Mark Twain Boyhood Home and Museum

Debbie

AED 356

AED 411 total

includes taxes & fees

17 Nov - 18 Nov

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

5. Motel 6 Hannibal, MO

2.9 km from Mark Twain Boyhood Home and Museum

Jared

AED 213

AED 246 total

includes taxes & fees

19 Oct - 20 Oct

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

6. Super 8 by Wyndham Hannibal

3 km from Mark Twain Boyhood Home and Museum

Betty

AED 227

AED 262 total

includes taxes & fees

21 Oct - 22 Oct

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

7. Sleep Inn & Suites Hannibal West

6.6 km from Mark Twain Boyhood Home and Museum

Patricia

AED 434

AED 505 total

includes taxes & fees

8 Nov - 9 Nov

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

8. Quality Inn & Suites Hannibal West

6.4 km from Mark Twain Boyhood Home and Museum

Gayle

AED 278

AED 323 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, a sofa, a desk, and a lamp.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

9. Comfort Inn & Suites - Hannibal

4.7 km from Mark Twain Boyhood Home and Museum

Jerry

AED 282

AED 336 total

includes taxes & fees

15 Nov - 16 Nov

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A hotel room with a dining area, kitchenette, and a door leading to a hallway.

A hotel room with two beds, a desk with a computer, a television, and a small seating area.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

10. Days Inn by Wyndham Hannibal

4.9 km from Mark Twain Boyhood Home and Museum

Christian

AED 231

AED 267 total

includes taxes & fees

25 Oct - 26 Oct

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A hotel room with two beds, a desk, a chair, and a telephone.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

11. Howard Johnson BY Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Debbie

AED 215

AED 250 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

12. Baymont by Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

brian

AED 203

AED 236 total

includes taxes & fees

18 Oct - 19 Oct

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Property class	Guest rating
Riverside Inn Hannibal	9.6 Exceptional 202 reviews	View
Lighthouse Inn & Suites	8.8 Excellent 47 reviews	View
Best Western On The River	8.6 Excellent 1,005 reviews	View
Garden House Bed and Breakfast	8.2 Very good 56 reviews	View
Motel 6 Hannibal, MO	7.4 Good 1,002 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Riverside Inn Hannibal

10/10 Excellent

"The accommodations were great! The location is perfect for touring downtown Hanibal. The only issue we had was make sure you dont choose pay in person as there is no front desk. Once the fees go through you recieve a text with the door codes."

Quality Inn & Suites Hannibal West

10/10 Excellent

"Hot breakfast options made for a great start to the day!"

Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee

10/10 Excellent

"Great location to have a home base to walk to sites, shops, and restaurants. Comfortable place to relax after long day of seeing sites. Bathroom is compact yet clean . Host was wonderful : stayed in touch to assure our needs were met ."

Motel 6 Hannibal, MO

10/10 Excellent

"Room was clean and staff was very pleasant"

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

10/10 Excellent

"Cute and spacious spot to stay. Great location- we were able to walk to everything we wanted to do in downtown Hannibal."

Garden House Bed and Breakfast

8/10 Good

"Beautiful Queen Ann B&B, was reasonably priced and within walking distance to the river and down town Hannibal attractions."

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

10/10 Excellent

"Very cute house, we enjoyed our stay. Only thing we didn't like was ants in the kitchen. We left a suggestion on how to solve the ant issue."

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

10/10 Excellent

"This is a cute unit in the heart of it all on Main Street. Very nicely designed and maintained. I looked up the history of the property and found out it was a drug store built in the late 1800s and operated until 1986. Now converted into a bar and grill at street level and this fun unit on the third floor. Just lovely. Very safe and secure. Parking is close and was readily available. Two drawbacks for me was that I looked everywhere and found no hairdryer. I also felt the cleaning fee which was almost as much as the nightly rate was very high for folks that stay one night like we did. A sliding scale for cleaning fees would be a good idea. If the fee was the same for three nights as it was for one night, I would find that reasonable. It was just too high for one night. All in all it was a wonderful stay. I hope the owners take my comments are constructive versus a criticism. They’ve made a lovely space for visitors to a magical place. Thanks so much."

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

8/10 Good

"We really enjoyed our stay and especially loved the cat hostess. We are both cat lovers and are without cats at the moment so that was just sweet. We were disappointed to find that breakfast wasn’t served at the bed-and-breakfast and which was advertised on the in the listing, but our host said that it was a separate add-on, Chris, our host was very helpful when we accidentally left a bag behind and we had to drive over and pick it up from him. He was very gracious to meet us."

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savor the top-notch restaurants.

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Planters Barn Theater

8.8/10 (22 reviews)

Enjoy a show at Planters Barn Theater, a storied theater in Hannibal. While in this walkable area, you can savor the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your travels to Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Bluff City Theater

7.6/10 (5 reviews)

Enjoy a show at Bluff City Theater, a theater with a story to tell in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your travels to Hannibal. While in this walkable area, you can savor the top-notch restaurants.

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Lovers Leap

8.8/10 (171 reviews)

Find out about the history of Hannibal with a stop at Lovers Leap. While in this walkable area, you can savor the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal with a visit to Riverview Park. While in this family-friendly area, you can savor the top-notch restaurants.

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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, check out the 40 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Garden House Bed and Breakfast.

How many hotels are there near Mark Twain Boyhood Home and Museum?

Expedia has 40 hotels and other accommodations within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to Mark Twain Boyhood Home and Museum.

Where can I learn more about changing or cancelling my trip in the area near Mark Twain Boyhood Home and Museum?

To access more information about changing or cancelling your stay near Mark Twain Boyhood Home and Museum, go to https://www.expedia.com/service/.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion, and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Bluff City Theater and Planters Barn Theater.

Find hotels near Mark Twain Boyhood Home and Museum, Hannibal from AED 236

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Lighthouse Inn & Suites

3. Best Western On The River

4. Garden House Bed and Breakfast

5. Motel 6 Hannibal, MO

6. Super 8 by Wyndham Hannibal

7. Sleep Inn & Suites Hannibal West

8. Quality Inn & Suites Hannibal West

9. Comfort Inn & Suites - Hannibal

10. Days Inn by Wyndham Hannibal

11. Howard Johnson BY Wyndham Hannibal

12. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Riverside Inn Hannibal

Quality Inn & Suites Hannibal West

Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee

Motel 6 Hannibal, MO

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

Garden House Bed and Breakfast

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

Planters Barn Theater

Jim's Journey: The Huck Finn Freedom Center

Bluff City Theater

Molly Brown Museum and Home

Lovers Leap

Riverview Park

Sodalis Nature Preserve

Frequently asked questions