Matlacha Isles Vacations
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Where to stay in Matlacha Isles
Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
Pelican
1 out of top 10 points of interest in this area
4.5/5(46 area reviews)
If you're spending some time in Pelican, Tarpon Point and Chabad Jewish Center are top sights worth seeing.
Matlacha Isles Hotel Deals
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is AED 1,466 per night from Feb 12 to Feb 13
AED 1,466
AED 1,726 total
12 Feb - 13 Feb
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
Nice room and perfect location
Reviewed on 1 February 2026
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is AED 1,088 per night from Feb 10 to Feb 11
AED 1,088
AED 1,397 total
10 Feb - 11 Feb
includes taxes & fees
8.8/10 Excellent! (1,858 reviews)
Excellent room and location
Reviewed on 7 February 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is AED 1,378 per night from Feb 11 to Feb 12
AED 1,378
AED 1,628 total
11 Feb - 12 Feb
includes taxes & fees
9/10 Wonderful! (1,581 reviews)
A really good looking resort. A great place to stay - directly on the beach with a great coffee shop and burger restaurant that we used whilst we were there! Easy to find, all the staff were fabulous and nice to have a daily housekeeping service as the sand gets everywhere! Check-in was easy and ...
Reviewed on 3 February 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Matlacha Isles
Four Mile Cove Ecological Preserve
Enjoy the beautiful sunsets and explore Four Mile Cove Ecological Preserve, a lovely green space in Cape Coral. Amble around this family-friendly area's beautiful beaches or attend a baseball game.
Palmetto-Pine Country Club
Enjoy a round of golf in Cape Coral at Palmetto-Pine Country Club. Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.